Magnesium sulfate
- Generic Name
- Magnesium sulfate
- Brand Names
- Concept Ob, Suflave, Suprep Bowel Prep Kit, Tis-U-sol
- Drug Type
- Small Molecule
- Chemical Formula
- MgO4S
- CAS Number
- 7487-88-9
- Unique Ingredient Identifier
- ML30MJ2U7I
- Background
A small colorless crystal used as an anticonvulsant, a cathartic, and an electrolyte replenisher in the treatment of pre-eclampsia and eclampsia. It causes direct inhibition of action potentials in myometrial muscle cells. Excitation and contraction are uncoupled, which decreases the frequency and force of contractions. (From AMA Drug Evaluations Annual, 1992, p1083)
- Indication
Used for immediate control of life-threatening convulsions in the treatment of severe toxemias (pre-eclampsia and eclampsia) of pregnancy and in the treatment of acute nephritis in children. Also indicated for replacement therapy in magnesium deficiency, especially in acute hypomagnesemia accompanied by signs of tetany similar to those of hypocalcemia. Also used in uterine tetany as a myometriat relaxant.
- Associated Conditions
- Constipation, Convulsions, Hypomagnesemia, Torsades de Pointes, Barium poisoning, Severe Exacerbation of asthma
- Associated Therapies
- Bowel preparation therapy, Soaking aid for minor sprains and bruises
Magnesium as Adjuvant for Sciatic Block
- First Posted Date
- 2014-07-23
- Last Posted Date
- 2024-08-26
- Lead Sponsor
- Campus Bio-Medico University
- Target Recruit Count
- 60
- Registration Number
- NCT02198547
- Locations
- 🇮🇹
Campus Bio-Medico, Rome, Italy
Effect of Perioperative Intravenous Lidocaine Infusion and Magnesium Infusion on the Functional Recovery After General Anesthesia in the Patients Undergoing Breast Mastectomy
- Conditions
- Interventions
- First Posted Date
- 2014-07-10
- Last Posted Date
- 2015-10-19
- Lead Sponsor
- Yonsei University
- Target Recruit Count
- 126
- Registration Number
- NCT02185859
- Locations
- 🇰🇷
Yonsei University, College of Medicine, Yonsei Health System, Yonsei Cancer Center, Seoul, Korea, Republic of
Addition of Magnesium Sulfate to Caudal to Prevent Postoperative Emergence Agitation.
- Conditions
- Interventions
- First Posted Date
- 2014-06-17
- Last Posted Date
- 2014-06-17
- Lead Sponsor
- Ain Shams University
- Target Recruit Count
- 70
- Registration Number
- NCT02164773
- Locations
- 🇪🇬
Ain Shams University, Cairo, Egypt
Efficacy of Magnesium Sulfate in the Treatment of Bronchiolitis
- Conditions
- Interventions
- First Posted Date
- 2014-05-23
- Last Posted Date
- 2016-08-16
- Lead Sponsor
- Hamad Medical Corporation
- Target Recruit Count
- 200
- Registration Number
- NCT02145520
- Locations
- 🇶🇦
Pediatric Emergency Center, Al Saad, Doha, Qatar
A Trial Comparing Treatment With the Springfusor Infusion Pump to the IV Magnesium Sulfate Regimen
- Conditions
- Interventions
- First Posted Date
- 2014-03-19
- Last Posted Date
- 2016-10-04
- Lead Sponsor
- Gynuity Health Projects
- Target Recruit Count
- 200
- Registration Number
- NCT02091401
- Locations
- 🇪🇬
El Galaa Teaching Hospital, Cairo, Egypt
🇪🇬Shatby Maternity Hospital, Alexandria, Egypt
Hyperalgesia and NMDA Receptor Antagonist
- First Posted Date
- 2014-03-14
- Last Posted Date
- 2014-03-14
- Lead Sponsor
- Seoul National University Bundang Hospital
- Target Recruit Count
- 90
- Registration Number
- NCT02087202
Atrial Fibrillation and Neuropathic Pain After Thoracotomy and Continuous Application of Magnesium Sulphate.
- Conditions
- Interventions
- First Posted Date
- 2013-12-11
- Last Posted Date
- 2013-12-11
- Lead Sponsor
- Dr. Horst Schmidt Klinik GmbH
- Target Recruit Count
- 100
- Registration Number
- NCT02008747
- Locations
- 🇩🇪
HSK, Wiesbaden, Germany
Effects of Magnesium Sulphate on Sugammadex Reversal of Rocuronium Induced Blockade in Gynaecology Patients
- Conditions
- Interventions
- First Posted Date
- 2013-10-30
- Last Posted Date
- 2014-02-25
- Lead Sponsor
- Kocaeli University
- Target Recruit Count
- 80
- Registration Number
- NCT01972659
- Locations
- 🇹🇷
Kocaeli University Hospital, Kocaeli, Turkey
Controlled Hypotension During Functional Endoscopic Sinus Surgery
- First Posted Date
- 2013-10-08
- Last Posted Date
- 2013-10-08
- Lead Sponsor
- TC Erciyes University
- Target Recruit Count
- 60
- Registration Number
- NCT01956981
Study of Human Non-Shivering Thermogenesis and Basal Metabolic Rate
- Conditions
- Interventions
- First Posted Date
- 2013-09-25
- Last Posted Date
- 2024-10-16
- Target Recruit Count
- 47
- Registration Number
- NCT01950520
- Locations
- 🇺🇸
National Institutes of Health Clinical Center, Bethesda, Maryland, United States
Drug Development Updates
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