Salbutamol
- Generic Name
- Salbutamol
- Brand Names
- Airomir, Airsupra, Combivent, Proair, Proventil, Ventolin
- Drug Type
- Small Molecule
- Chemical Formula
- C13H21NO3
- CAS Number
- 18559-94-9
- Unique Ingredient Identifier
- QF8SVZ843E
- Background
Salbutamol is a short-acting, selective beta2-adrenergic receptor agonist used in the treatment of asthma and COPD. It is 29 times more selective for beta2 receptors than beta1 receptors giving it higher specificity for pulmonary beta receptors versus beta1-adrenergic receptors located in the heart. Salbutamol is formulated as a racemic mixture of the R- and...
- Indication
Salbutamol is indicated for (i) the symptomatic relief and prevention of bronchospasm due to bronchial asthma, chronic bronchitis, reversible obstructive airway disease, and other chronic bronchopulmonary disorders in which bronchospasm is a complicating factor, and/or (ii) the acute prophylaxis against exercise-induced bronchospasm and other stimuli known t...
- Associated Conditions
- Asthma, Asthmatic Bronchitis, Bronchial Asthma, Bronchoconstriction, Bronchospasm, Chronic Asthma, Chronic Bronchitis, Cough, Emphysema, Exacerbation of asthma, Exercise-Induced Bronchospasm, Hyperkalemia, Wheezing, Excess mucus or phlegm
- Associated Therapies
- Airway secretion clearance therapy, Bronchodilation
Functional Studies of Novel Genes Mutated in Primary Ciliary Dyskinesia II: Genotype to Phenotype
- Conditions
- Interventions
- First Posted Date
- 2021-05-25
- Last Posted Date
- 2024-08-26
- Lead Sponsor
- University of North Carolina, Chapel Hill
- Target Recruit Count
- 30
- Registration Number
- NCT04901715
- Locations
- 🇺🇸
University of North Carolina Chapel Hill, Chapel Hill, North Carolina, United States
Effect of Fluticasone Furoate/Vilanterol on EIA in Adolescents
- Conditions
- Interventions
- First Posted Date
- 2021-02-11
- Last Posted Date
- 2021-02-11
- Lead Sponsor
- Rambam Health Care Campus
- Target Recruit Count
- 92
- Registration Number
- NCT04750603
- Locations
- 🇮🇱
Rambam Medical Center, Haifa, Israel
A 24-Week Treatment Study to Compare Standard of Care Versus the eMDPI DS in Participants 13 Years or Older With Asthma
- Conditions
- Interventions
- First Posted Date
- 2020-12-21
- Last Posted Date
- 2023-03-14
- Lead Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
- Target Recruit Count
- 427
- Registration Number
- NCT04677959
- Locations
- 🇺🇸
Teva Investigational Site 14974, Fountain Valley, California, United States
🇺🇸Teva Investigational Site 14982, Los Angeles, California, United States
🇺🇸Teva Investigational Site 14955, Fort Lauderdale, Florida, United States
Physiologic Performance Response to Salbutamol
- First Posted Date
- 2020-11-04
- Last Posted Date
- 2020-11-04
- Lead Sponsor
- University of Copenhagen
- Target Recruit Count
- 20
- Registration Number
- NCT04615611
Bronchodilators for Wheeze in Young Children Presenting to Primary Care: a Randomised, Placebo-controlled, Multicentre, Parallel Group Trial
- First Posted Date
- 2020-10-12
- Last Posted Date
- 2021-07-23
- Lead Sponsor
- UMC Utrecht
- Registration Number
- NCT04584034
Mitochondrial Dysfunction and Insulin Resistance in Skeletal Muscle
- Conditions
- Interventions
- First Posted Date
- 2020-09-22
- Last Posted Date
- 2021-12-02
- Lead Sponsor
- University of Copenhagen
- Target Recruit Count
- 10
- Registration Number
- NCT04558190
- Locations
- 🇩🇰
August Krogh Building, Copenhagen, Denmark
A First in Human Study to Evaluate the Safety, Tolerability and Pharmacokinetics of Single and Multiple Ascending Doses of Inhaled ETD002 in Healthy Subjects
- First Posted Date
- 2020-07-28
- Last Posted Date
- 2021-05-21
- Lead Sponsor
- Enterprise Therapeutics Ltd
- Target Recruit Count
- 80
- Registration Number
- NCT04488705
- Locations
- 🇬🇧
Hammersmith Medicines Research, London, United Kingdom
Efficacy and Safety Study of Mepolizumab 100 Milligram (mg) Subcutaneous (SC) in Indian Participants Aged Greater Than or Equal to (>=) 18 Years With Severe Eosinophilic Asthma
- First Posted Date
- 2020-02-19
- Last Posted Date
- 2024-12-10
- Lead Sponsor
- GlaxoSmithKline
- Target Recruit Count
- 100
- Registration Number
- NCT04276233
- Locations
- 🇮🇳
GSK Investigational Site, Pune, India
Mechanisms for Dyspnea on Exertion in Children With Obesity and Asthma: Distinct Physiological Phenotypes
- Conditions
- Interventions
- First Posted Date
- 2019-12-03
- Last Posted Date
- 2023-11-07
- Lead Sponsor
- Ohio State University
- Registration Number
- NCT04184609
- Locations
- 🇺🇸
The Ohio State University, Columbus, Ohio, United States
Insulin Dextrose Infusion vs Nebulized Salbutamol vs Combination of Salbutamol and Insulin Dextrose in Acute Hyperkalemia
- First Posted Date
- 2019-07-09
- Last Posted Date
- 2024-04-30
- Lead Sponsor
- Nantes University Hospital
- Target Recruit Count
- 525
- Registration Number
- NCT04012138
- Locations
- 🇫🇷
Agen Hospital, Agen, France
🇫🇷Angers University Hospital, Angers, France
🇫🇷University Hospital, Clermont-Ferrand, Clermont-Ferrand, France
Drug Development Updates
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