Salbutamol
- Generic Name
- Salbutamol
- Brand Names
- Airomir, Airsupra, Combivent, Proair, Proventil, Ventolin
- Drug Type
- Small Molecule
- Chemical Formula
- C13H21NO3
- CAS Number
- 18559-94-9
- Unique Ingredient Identifier
- QF8SVZ843E
- Background
Salbutamol is a short-acting, selective beta2-adrenergic receptor agonist used in the treatment of asthma and COPD. It is 29 times more selective for beta2 receptors than beta1 receptors giving it higher specificity for pulmonary beta receptors versus beta1-adrenergic receptors located in the heart. Salbutamol is formulated as a racemic mixture of the R- and...
- Indication
Salbutamol is indicated for (i) the symptomatic relief and prevention of bronchospasm due to bronchial asthma, chronic bronchitis, reversible obstructive airway disease, and other chronic bronchopulmonary disorders in which bronchospasm is a complicating factor, and/or (ii) the acute prophylaxis against exercise-induced bronchospasm and other stimuli known t...
- Associated Conditions
- Asthma, Asthmatic Bronchitis, Bronchial Asthma, Bronchoconstriction, Bronchospasm, Chronic Asthma, Chronic Bronchitis, Cough, Emphysema, Exacerbation of asthma, Exercise-Induced Bronchospasm, Hyperkalemia, Wheezing, Excess mucus or phlegm
- Associated Therapies
- Airway secretion clearance therapy, Bronchodilation
Physiological Response to Salbutamol and Exercise
- First Posted Date
- 2019-04-03
- Last Posted Date
- 2020-11-03
- Lead Sponsor
- University of Copenhagen
- Target Recruit Count
- 40
- Registration Number
- NCT03902106
- Locations
- 🇩🇰
August Krogh Building, Copenhagen, Denmark
A 12-Week Treatment Study to Evaluate the Effectiveness of Albuterol Multidose Dry Powder Inhaler With Integrated Electronic Module Digital System (eMDPI DS) in Participants13 Years or Older With Asthma
- First Posted Date
- 2019-03-26
- Last Posted Date
- 2022-12-07
- Lead Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
- Target Recruit Count
- 333
- Registration Number
- NCT03890666
- Locations
- 🇺🇸
Teva Investigational Site 14197, Aventura, Florida, United States
🇺🇸Teva Investigational Site 14302, Los Angeles, California, United States
🇺🇸Teva Investigational Site 14195, Savannah, Georgia, United States
Salbutamol Administration by Nebulizer Versus Metered Dose Inhaler With Spacer in Asthma in Children
- Conditions
- Interventions
- First Posted Date
- 2019-01-25
- Last Posted Date
- 2019-04-04
- Lead Sponsor
- Suez Canal University
- Target Recruit Count
- 60
- Registration Number
- NCT03816267
- Locations
- 🇪🇬
Suez Canal University Hospital, Ismailia, Egypt
Nebulized Epinephrine vs. Salbutamol in Bronchiolitis Among Children
- Conditions
- Interventions
- First Posted Date
- 2019-01-24
- Last Posted Date
- 2022-08-30
- Lead Sponsor
- Makassed General Hospital
- Target Recruit Count
- 90
- Registration Number
- NCT03814954
- Locations
- 🇱🇧
Makassed General Hospital, Beirut, Lebanon
Phosphodiesterase 4 Gene Variant and Salbutamol Response in Persistent Childhood Asthma
- Conditions
- First Posted Date
- 2018-07-19
- Last Posted Date
- 2022-11-01
- Lead Sponsor
- Assistance Publique - Hôpitaux de Paris
- Target Recruit Count
- 99
- Registration Number
- NCT03592212
- Locations
- 🇫🇷
Hôpital Necker -Enfants Malades, Paris, France
A Safety and Efficacy Study of Mepolizumab in Subjects With Severe Asthma
- Conditions
- Interventions
- First Posted Date
- 2018-06-19
- Last Posted Date
- 2022-10-21
- Lead Sponsor
- GlaxoSmithKline
- Target Recruit Count
- 300
- Registration Number
- NCT03562195
- Locations
- 🇨🇳
GSK Investigational Site, Tianjin, China
CF Bronchodilation
- Conditions
- Interventions
- First Posted Date
- 2018-05-11
- Last Posted Date
- 2023-12-14
- Lead Sponsor
- University of British Columbia
- Target Recruit Count
- 20
- Registration Number
- NCT03522831
- Locations
- 🇨🇦
UBC Cardiopulmonary Exercise Physiology Laboratory, Vancouver, British Columbia, Canada
Status Asthmaticus on the PICU; Intravenous Salbutamol
- Conditions
- Interventions
- First Posted Date
- 2018-04-10
- Last Posted Date
- 2020-07-30
- Lead Sponsor
- Erasmus Medical Center
- Target Recruit Count
- 58
- Registration Number
- NCT03493503
- Locations
- 🇳🇱
Erasmus MC, Rotterdam, Zuid-Holland, Netherlands
Anti-IgE Monoclonal Antibody Treatment in Patients With Allergic Asthma.
- Conditions
- Interventions
- First Posted Date
- 2018-03-19
- Last Posted Date
- 2021-10-11
- Lead Sponsor
- Shanghai Biomabs Pharmaceutical Co., Ltd.
- Target Recruit Count
- 393
- Registration Number
- NCT03468790
- Locations
- 🇨🇳
The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China
🇨🇳The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China
High-flow Nasal Cannula Nebulization of Beta 2 Adrenergic Agonist During Acute Exacerbation of Chronic Obstructive Pulmonary Disease
- Conditions
- Interventions
- First Posted Date
- 2018-02-28
- Last Posted Date
- 2019-02-12
- Lead Sponsor
- Poitiers University Hospital
- Target Recruit Count
- 25
- Registration Number
- NCT03449056
- Locations
- 🇫🇷
C.H.U. de Poitiers, Poitiers, France
Drug Development Updates
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