Clopidogrel
- Generic Name
- Clopidogrel
- Brand Names
- Duoplavin, Plavix, Zyllt, Clopidogrel BGR (previously Zylagren), Clopidogrel TAD, Clopidogrel ratiopharm, Clopidogrel Zentiva (previously Clopidogrel Winthrop), Clopidogrel Krka, Clopidogrel Krka d.d. (previously Zopya), Clopidogrel Teva (hydrogen sulphate), Clopidogrel HCS, Iscover, Grepid, Clopidogrel Taw Pharma (previously Clopidogrel Mylan), Clopidogrel Viatris (previously Clopidogrel Taw Pharma)
- Drug Type
- Small Molecule
- Chemical Formula
- C16H16ClNO2S
- CAS Number
- 113665-84-2
- Unique Ingredient Identifier
- A74586SNO7
- Background
Clopidogrel is a prodrug of a platelet inhibitor used to reduce the risk of myocardial infarction and stroke. Clopidogrel is indicated to reduce the risk of myocardial infarction for patients with non-ST elevated acute coronary syndrome (ACS), patients with ST-elevated myocardial infarction, and in recent MI, stroke, or established peripheral arterial diseas...
- Indication
1.用于新近心肌梗死、新近脑卒中或确诊的周围动脉病变患者，可减少新的缺血性脑卒中、心肌梗死和死亡等心脑血管事件的符合终点；
2.用于急性冠状动脉综合征（不稳定心绞痛和非ST段抬高心肌梗死）患者；
3.用于冠状动脉支架置入术后预防支架内血栓形成（与阿司匹林联用）。
- Associated Conditions
- Acute Coronary Syndrome (ACS), Acute Myocardial Infarction (AMI), Cardiovascular Events, Atherothrombotic events
- Associated Therapies
- -
Clopidogrel and Response Variability Investigation Study 2
- First Posted Date
- 2009-01-14
- Last Posted Date
- 2012-12-11
- Lead Sponsor
- Assistance Publique - Hôpitaux de Paris
- Target Recruit Count
- 109
- Registration Number
- NCT00822666
- Locations
- 🇫🇷
Hopital la Pitié-Salpétrière Institut de cardiologie, Paris, France
COMbination of Clopidogrel and Aspirin for Prevention of Early REcurrence in Acute Atherothrombotic Stroke
- Conditions
- Interventions
- First Posted Date
- 2008-12-24
- Last Posted Date
- 2014-02-28
- Lead Sponsor
- Sanofi
- Target Recruit Count
- 358
- Registration Number
- NCT00814268
- Locations
- 🇰🇷
Sanofi-Aventis Administrative Office, Seoul, Korea, Republic of
Determining Genetic Role in Treatment Response to Anti-Platelet Interventions (The PAPI Study)
- Conditions
- Interventions
- First Posted Date
- 2008-11-27
- Last Posted Date
- 2022-02-24
- Lead Sponsor
- University of Maryland, Baltimore
- Target Recruit Count
- 682
- Registration Number
- NCT00799396
- Locations
- 🇺🇸
Amish Research Clinic, Lancaster, Pennsylvania, United States
Clopidogrel For the Prevention of New Onset Migraine Headache Following Transcatheter Closure of Atrial Septal Defects
- First Posted Date
- 2008-11-27
- Last Posted Date
- 2019-02-26
- Lead Sponsor
- Laval University
- Target Recruit Count
- 220
- Registration Number
- NCT00799045
- Locations
- 🇨🇦
Hopital Laval, Quebec, Canada
Stem Cell Mobilization by G-CSF to Treat Severe Peripheral Artery Disease
- Conditions
- Interventions
- First Posted Date
- 2008-11-25
- Last Posted Date
- 2015-04-01
- Lead Sponsor
- Washington University School of Medicine
- Target Recruit Count
- 32
- Registration Number
- NCT00797056
- Locations
- 🇺🇸
Washington University School of Medicine, St. Louis, Missouri, United States
Study of Optimal Clopidogrel Duration in Patients Receiving Drug Eluting Stents (SCORE Trial)
- First Posted Date
- 2008-10-29
- Last Posted Date
- 2018-09-13
- Lead Sponsor
- North Texas Veterans Healthcare System
- Target Recruit Count
- 167
- Registration Number
- NCT00781573
- Locations
- 🇺🇸
Dallas Veterans Hospital, Dallas, Texas, United States
🇬🇷The Onassis cardiac Surgery Centre, Athens, Greece
🇮🇳Escorts Health Institute & Research Centre Ltd, New Delhi, India
Effect of Naproxen, Aspirin, Celecoxib, or Clopidogrel on the Healing of Stomach and Intestinal Ulcers
- Conditions
- Interventions
- First Posted Date
- 2008-10-23
- Last Posted Date
- 2008-10-23
- Lead Sponsor
- Research Associates of New York, LLP
- Target Recruit Count
- 125
- Registration Number
- NCT00778193
- Locations
- 🇺🇸
Research Associates of New York, New York, New York, United States
Triple Therapy in Patients on Oral Anticoagulation After Drug Eluting Stent Implantation
- Conditions
- Interventions
- First Posted Date
- 2008-10-21
- Last Posted Date
- 2016-08-30
- Lead Sponsor
- Deutsches Herzzentrum Muenchen
- Target Recruit Count
- 614
- Registration Number
- NCT00776633
- Locations
- 🇩🇪
Deutsches Herzzentrum München, Munich, Germany
🇩🇰Aarhus University Hospital, Aarhus, Denmark
🇩🇪1. Medizinische Klinik, Klinikum rechts der Isar, München, Germany
Anti-Inflammatory and Anti-Platelet Effect of Clopidogrel and Aspirin vs Aspirin Alone in Symptomatic Polyvascular Disease and in Patients With Multiple Recurrent Cardiovascular Events
- Conditions
- Interventions
- First Posted Date
- 2008-10-20
- Last Posted Date
- 2008-10-20
- Lead Sponsor
- Catholic University of the Sacred Heart
- Target Recruit Count
- 213
- Registration Number
- NCT00775762
- Locations
- 🇮🇹
Catholic University of the Sacred Heart, Department of Cardiovascular Medicine, Rome, Italy
Clopidogrel Versus Adenosin in Non Urgent Percutaneous Coronary Intervention (PCI)
- Conditions
- Interventions
- First Posted Date
- 2008-09-12
- Last Posted Date
- 2009-05-06
- Lead Sponsor
- University of Roma La Sapienza
- Target Recruit Count
- 60
- Registration Number
- NCT00751491
- Locations
- 🇮🇹
Policlinico Umberto I, Rome, Italy
Drug Development Updates
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