Epinephrine

Generic Name: Epinephrine

Brand Names: Adrenalin, Allerject, Anapen, Articadent, Astracaine, Auvi-Q, Citanest, Citanest Forte, Emerade, Epipen, Lignospan, Marcaine, Marcaine With Epinephrine, Octocaine, Octocaine With Epinephrine, Orabloc, Scandonest, Sensorcaine, Sensorcaine With Epinephrine, Septanest, Septocaine, Symjepi, Ultacan, Ultracaine, Vivacaine, Xylocaine, Xylocaine With Epinephrine, Zorcaine, Eurneffy

Drug Type: Small Molecule

Chemical Formula: C_₉H_₁₃NO_₃

CAS Number: 51-43-4

Unique Ingredient Identifier: YKH834O4BH

Background: Epinephrine, also known as adrenaline, is a hormone and neurotransmitter and produced by the adrenal glands that can also be used as a drug due to its various important functions. Though it has long been used in the treatment of hypersensitivity reactions, epinephrine in the auto-injector form (EpiPen) has been available since 1987 in the USA. Many new produ...

Indication: Epinephrine injection is indicated in the emergency treatment of type I allergic reactions, including anaphylaxis. It is also used to increase mean arterial blood pressure in adult patients with hypotension associated with septic shock.
...

Associated Conditions: Anaphylaxis, Angioneurotic Edema, Bleeding, Bronchospasm, Complete Heart Block, Hypotension, Idiopathic Anaphylaxis, Laryngotracheobronchitis, Mild Intermittent Asthma, Nasal Congestion, Open Angle Glaucoma (OAG), Respiratory Distress, Severe Asthma, Syncope, Type I Hypersensitivity, Urticaria, Uterine Contractions, Ventricular Fibrillation, Resuscitation in cardiac arrest following anesthetic accidents, Severe hypersensitivity reactions, Unresponsive Asystole, Unresponsive Bradycardia

Associated Therapies: -

Clinical Trials

Hypoglycemia Associated Autonomic Failure in Type 1 DM, Q5

Not Applicable

Withdrawn

Conditions: Type 1 Diabetes

Interventions: Drug: epinephrine

First Posted Date: 2008-01-31

Last Posted Date: 2014-12-11

Lead Sponsor: Vanderbilt University

Registration Number: NCT00605774

Efficacy of Multimodal Peri- and Intraarticular Drug Injections in Total Knee Arthroplasty

Phase 4

Completed

Conditions: Osteoarthritis of the Knee

Interventions: Drug: ropivacaine
Drug: adrenaline
Drug: fentanyl
Drug: ketorolac
Drug: bupivacaine
Drug: morphine

First Posted Date: 2007-11-22

Last Posted Date: 2011-08-08

Lead Sponsor: Asker & Baerum Hospital

Target Recruit Count: 102

Registration Number: NCT00562627

Locations: 🇳🇴
Asker and Baerum Hospital, Rud, Norway

Low-dose Epinephrine Infusion Tests in Adolescent and Pediatric Patients

Not Applicable

Terminated

Conditions: Congenital Disorders

Interventions: Drug: Epinephrine

First Posted Date: 2007-10-24

Last Posted Date: 2017-12-06

Lead Sponsor: Emory University

Target Recruit Count: 7

Registration Number: NCT00548886

Locations: 🇺🇸
Children's Healthcare of Atlanta, Atlanta, Georgia, United States

The Effects of Adrenaline and Milrinone in Patients With Myocardial Dysfunction After CABG

Phase 3

Completed

Conditions: Cardiac Output, Low

First Posted Date: 2007-03-12

Last Posted Date: 2015-06-03

Lead Sponsor: University of Luebeck

Target Recruit Count: 60

Registration Number: NCT00446017

Treatment of Ventricular Tachyarrhythmias Refractory To Shock With Beta Blockers: The SHOCK and BLOCK Trial

Phase 2

Terminated

Conditions: Cardiac Arrest
Sudden Cardiac Death
Tachycardia, Ventricular
Ventricular Fibrillation

Interventions: Drug: Epinephrine
Drug: Metoprolol

First Posted Date: 2006-11-22

Last Posted Date: 2017-05-25

Lead Sponsor: David Haines, MD

Target Recruit Count: 7

Registration Number: NCT00401882

Locations: 🇺🇸
William Beaumont Hospital, Royal Oak, Michigan, United States

Comparing Vasopressin and Adrenaline in Patients With Cardiac Arrest

Phase 3

Completed

Conditions: Cardiac Arrest

Interventions: Drug: Adrenaline
Drug: Vasopressin

First Posted Date: 2006-08-01

Last Posted Date: 2017-03-17

Lead Sponsor: Singapore General Hospital

Target Recruit Count: 727

Registration Number: NCT00358579

Locations: 🇸🇬
Changi General Hospital, Singapore, Singapore
🇸🇬
Singapore General Hospital, Singapore, Singapore
🇸🇬
National University Hospital, Singapore, Singapore

and more 1 locations