Epinephrine

Generic Name
Epinephrine
Brand Names
Adrenalin, Allerject, Anapen, Articadent, Astracaine, Auvi-Q, Citanest, Citanest Forte, Emerade, Epipen, Lignospan, Marcaine, Marcaine With Epinephrine, Octocaine, Octocaine With Epinephrine, Orabloc, Scandonest, Sensorcaine, Sensorcaine With Epinephrine, Septanest, Septocaine, Symjepi, Ultacan, Ultracaine, Vivacaine, Xylocaine, Xylocaine With Epinephrine, Zorcaine, Eurneffy
Drug Type
Small Molecule
Chemical Formula
C9H13NO3
CAS Number
51-43-4
Unique Ingredient Identifier
YKH834O4BH
Background

Epinephrine, also known as adrenaline, is a hormone and neurotransmitter and produced by the adrenal glands that can also be used as a drug due to its various important functions. Though it has long been used in the treatment of hypersensitivity reactions, epinephrine in the auto-injector form (EpiPen) has been available since 1987 in the USA. Many new produ...

Indication

Epinephrine injection is indicated in the emergency treatment of type I allergic reactions, including anaphylaxis. It is also used to increase mean arterial blood pressure in adult patients with hypotension associated with septic shock.
...

Associated Conditions
Anaphylaxis, Angioneurotic Edema, Bleeding, Bronchospasm, Complete Heart Block, Hypotension, Idiopathic Anaphylaxis, Laryngotracheobronchitis, Mild Intermittent Asthma, Nasal Congestion, Open Angle Glaucoma (OAG), Respiratory Distress, Severe Asthma, Syncope, Type I Hypersensitivity, Urticaria, Uterine Contractions, Ventricular Fibrillation, Resuscitation in cardiac arrest following anesthetic accidents, Severe hypersensitivity reactions, Unresponsive Asystole, Unresponsive Bradycardia
Associated Therapies
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Tranexamic Acid Versus Adrenaline for Controlling Iatrogenic Endobronchial Bleeding

Not Applicable
Completed
Conditions
Interventions
First Posted Date
2021-02-25
Last Posted Date
2022-02-24
Lead Sponsor
Clinical Hospital Centre Zagreb
Target Recruit Count
130
Registration Number
NCT04771923
Locations
🇭🇷

Clinical Hospital Centre Zagreb, Zagreb, Croatia

Management of Shock in Children With SAM or Severe Underweight and Diarrhea

First Posted Date
2021-02-11
Last Posted Date
2022-12-20
Lead Sponsor
International Centre for Diarrhoeal Disease Research, Bangladesh
Target Recruit Count
135
Registration Number
NCT04750070
Locations
🇧🇩

Icddr,B, Dhaka, Bangladesh

Adrenaline for the Treatment of No-Reflow in Normotensive Patients

First Posted Date
2021-01-07
Last Posted Date
2021-05-21
Lead Sponsor
National Institute of Cardiovascular Diseases, Pakistan
Target Recruit Count
201
Registration Number
NCT04699110
Locations
🇵🇰

National Institute of Cardiovascular Diseases, Karachi, Sindh, Pakistan

Comparison of the Efficacy of Irrigation With Epinephrine or Tranexamic Acid on Visual Clarity

Not Applicable
Completed
Conditions
Interventions
First Posted Date
2020-11-13
Last Posted Date
2020-11-13
Lead Sponsor
Haseki Training and Research Hospital
Target Recruit Count
100
Registration Number
NCT04628676
Locations
🇹🇷

Haseki Training and Research Hospital, Istanbul, Turkey

Tranexamic Acid to Improve Arthroscopic Visualization in Shoulder Surgery

First Posted Date
2020-10-20
Last Posted Date
2024-04-02
Lead Sponsor
Panam Clinic
Target Recruit Count
128
Registration Number
NCT04594408
Locations
🇨🇦

Pan Am Clinic, Winnipeg, Manitoba, Canada

The EPIVER Randomized Controlled Trial

First Posted Date
2020-10-05
Last Posted Date
2024-04-29
Lead Sponsor
Tomsk National Research Medical Center of the Russian Academy of Sciences
Target Recruit Count
104
Registration Number
NCT04573751
Locations
🇷🇺

Cardiology Research Institute, Tomsk NRMC, Tomsk, Tomsk Region, Russian Federation

Effects of Pre-emptive Scalp Infiltration With Low-dose Ketorolac and Ropivacaine for Postoperative Pain

First Posted Date
2020-05-08
Last Posted Date
2020-09-09
Lead Sponsor
Beijing Tiantan Hospital
Target Recruit Count
40
Registration Number
NCT04380298

Comparison of Articaine and Prilocaine for Extraction of Maxillary Teeth

First Posted Date
2020-01-22
Last Posted Date
2020-01-22
Lead Sponsor
Taibah University
Target Recruit Count
95
Registration Number
NCT04236115
Locations
🇸🇦

Taibah University, Medina, Saudi Arabia

Tranexamic Acid Versus Epinephrine During Exploratory Tympanotomy

Not Applicable
Completed
Conditions
Interventions
First Posted Date
2019-12-05
Last Posted Date
2020-04-21
Lead Sponsor
Assiut University
Target Recruit Count
60
Registration Number
NCT04188184
Locations
🇪🇬

Faculty of Medicine, Asyut, Egypt

🇪🇬

Assiut university, Assiut, Egypt

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