Nebivolol

Generic Name
Nebivolol
Brand Names
Bystolic
Drug Type
Small Molecule
Chemical Formula
C22H25F2NO4
CAS Number
118457-14-0
Unique Ingredient Identifier
030Y90569U
Background

Nebivolol is a racemic mixture of 2 enantiomers where one is a beta adrenergic antagonist and the other acts as a cardiac stimulant without beta adrenergic activity. Treatment with nebivolol leads to a greater decrease in systolic and diastolic blood pressure than atenolol, propranolol, or pindolol. Nebivolol and other beta blockers are generally not first l...

Indication

Nebivolol is indicated to treat hypertension.

Associated Conditions
Hypertension
Associated Therapies
-

Danish Trial of Beta Blocker Treatment After Myocardial Infarction Without Reduced Ejection Fraction

First Posted Date
2018-12-19
Last Posted Date
2024-12-11
Lead Sponsor
Bispebjerg Hospital
Target Recruit Count
2760
Registration Number
NCT03778554
Locations
🇩🇰

Bispebjerg Hospital, Dept. of Cardiology Y builing 67, 1.floor, Bispebjerg Bakke 23, Copenhagen, Denmark

Effect of Olmesartan and Nebivolol on Ambulatory Blood Pressure and Arterial Stiffness in Acute Stage of Ischemic Stroke

First Posted Date
2018-09-04
Last Posted Date
2020-01-07
Lead Sponsor
Aristotle University Of Thessaloniki
Target Recruit Count
60
Registration Number
NCT03655964
Locations
🇬🇷

AHEPA University Hospital, Thessaloniki, Greece

Treatment of OSA Associated Hypertension With Nebivolol or Hydrochlorothiazide

Phase 4
Completed
Conditions
Interventions
First Posted Date
2016-03-16
Last Posted Date
2020-10-19
Lead Sponsor
University of California, San Diego
Target Recruit Count
41
Registration Number
NCT02710071

Comparative Effects of Nebivolol and Carvedilol on Diastolic Function in the Elderly Heart Failure Patients

Not Applicable
Conditions
Interventions
First Posted Date
2015-12-02
Last Posted Date
2018-02-05
Lead Sponsor
Dong-A University
Target Recruit Count
62
Registration Number
NCT02619526
Locations
🇰🇷

Department of Internal Medicine,Dong-A University College of Medicine, Busan, Korea, Republic of

Dose Response and Receptor Selectivity of Beta-blocker Effects on Bone Metabolism

First Posted Date
2015-06-10
Last Posted Date
2019-02-06
Lead Sponsor
Mayo Clinic
Target Recruit Count
165
Registration Number
NCT02467400
Locations
🇺🇸

Mayo Clinic in Rochester, Rochester, Minnesota, United States

Comparative Study of the Effects of Telmisartan and Nebivolol

Phase 4
Conditions
Interventions
First Posted Date
2014-02-07
Last Posted Date
2014-02-07
Lead Sponsor
Aristotle University Of Thessaloniki
Target Recruit Count
80
Registration Number
NCT02057328
Locations
🇬🇷

Hypertension-ABPM Center 3rd department of Internal Medicine, Thessaloniki, Greece

Improving Treatment Personalization of Pulmonary Hypertension Associated With Diastolic Heart Failure

First Posted Date
2014-02-03
Last Posted Date
2022-02-10
Lead Sponsor
University of Florida
Target Recruit Count
11
Registration Number
NCT02053246
Locations
🇺🇸

University of Florida, Gainesville, Florida, United States

Non-invasive Haemodynamic Assessment in Hypertension

First Posted Date
2013-11-27
Last Posted Date
2018-03-13
Lead Sponsor
Military Institute od Medicine National Research Institute
Target Recruit Count
144
Registration Number
NCT01996085
Locations
🇵🇱

Military Institute of Medicine, Warsaw, Mazovia, Poland

Effect of Nebivolol on the Blood Flow in Hearts of Adults With High Blood Pressure and Abnormal Filling of Heart

First Posted Date
2013-10-11
Last Posted Date
2017-11-24
Lead Sponsor
Icahn School of Medicine at Mount Sinai
Target Recruit Count
70
Registration Number
NCT01961323
Locations
🇺🇸

Icahn School of Medicine at Mount Sinai, New York, New York, United States

Safety Study of Nebivolol for COPD Patients

Phase 2
Withdrawn
Conditions
Interventions
First Posted Date
2013-09-11
Last Posted Date
2016-01-12
Lead Sponsor
University of Chicago
Registration Number
NCT01939990
Locations
🇺🇸

University of Chicago Medical Center, Chicago, Illinois, United States

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