Clonidine
- Generic Name
- Clonidine
- Brand Names
- Catapres, Catapres-TTS, Catapres-tts-1, Duraclon, Kapvay, Nexiclon XR
- Drug Type
- Small Molecule
- Chemical Formula
- C9H9Cl2N3
- CAS Number
- 4205-90-7
- Unique Ingredient Identifier
- MN3L5RMN02
- Background
Clonidine is an imidazole derivate that acts as an agonist of alpha-2 adrenoceptors. This activity is useful for the treatment of hypertension, severe pain, and ADHD.
Clonidine was granted FDA approval on 3 September 1974.
- Indication
Clonidine tablets and transdermal systems are indicated for the treatment of hypertension alone or in combination with other medications. A clonidine injection is indicated for use with opiates in the treatment of severe cancer pain where opiates alone are insufficient. An extended release tablet of clonidine is indicated for the treatment of ADHD either alo...
- Associated Conditions
- Attention Deficit Hyperactivity Disorder (ADHD), Defiant Disorder, Oppositional, Gilles de la Tourette's Syndrome, Hot Flashes, Human Growth Hormone Deficiency, Hypertension, Opioid Withdrawal (Disorder), Pheochromocytoma, Postherpetic Neuralgia, Sialorrhea caused by clozapine, Diabetic diarrhea, Methadone withdrawal, Severe Cancer pain
- Associated Therapies
- Smoking, Cessation
The PREVENT AGITATION Trial II - Children ≤1 Year
- First Posted Date
- 2021-10-25
- Last Posted Date
- 2024-04-11
- Lead Sponsor
- Rigshospitalet, Denmark
- Target Recruit Count
- 336
- Registration Number
- NCT05091242
- Locations
- 🇩🇰
Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
Dexmedetomidine or Clonidine Infusion for Prevention of Delirium After Open Heart Surgery
- Conditions
- Interventions
- First Posted Date
- 2021-08-31
- Last Posted Date
- 2024-04-30
- Lead Sponsor
- Oslo University Hospital
- Target Recruit Count
- 900
- Registration Number
- NCT05029050
- Locations
- 🇳🇴
Oslo University Hospital Rikshospitalet, Oslo, Norway
🇳🇴Oslo University Hospital Ullevål, Oslo, Norway
🇳🇴University Hospital of North Norway, Tromsø, Norway
Clonidine for Analgesia to Preterm Infants During Neonatal Intensive Care
- Conditions
- Interventions
- First Posted Date
- 2021-06-16
- Last Posted Date
- 2023-08-04
- Lead Sponsor
- Region Skane
- Target Recruit Count
- 40
- Registration Number
- NCT04928651
- Locations
- 🇸🇪
Skane University Hospital, Lund, Sweden
🇸🇪Marco Bartocci, Stockholm, Sweden
Clonidine to Prevent Delirium After Electroconvulsive Therapy.
- Conditions
- Interventions
- First Posted Date
- 2021-04-01
- Last Posted Date
- 2024-10-30
- Lead Sponsor
- Insel Gruppe AG, University Hospital Bern
- Target Recruit Count
- 130
- Registration Number
- NCT04828226
- Locations
- 🇨🇭
Department of Anaesthesiology and Pain Medicine, Bern University Hospital, University of Bern, Bern, Switzerland
Clonidine vs. Dexmedetomidine in Agitated Delirium in Intensive Care Patients
- First Posted Date
- 2021-02-17
- Last Posted Date
- 2021-02-17
- Lead Sponsor
- Erasme University Hospital
- Target Recruit Count
- 50
- Registration Number
- NCT04758936
- Locations
- 🇧🇪
Clinique Saint-Pierre, Ottignies, Belgium
🇧🇪CUB Erasme Hospital ULB, Bruxelles, Belgium
🇧🇪Civil hospital Marie Curie, Charleroi, Belgium
Clonidine for Tourniquet-related Pain in Children
- First Posted Date
- 2020-09-25
- Last Posted Date
- 2021-09-10
- Lead Sponsor
- Odense University Hospital
- Target Recruit Count
- 20
- Registration Number
- NCT04564430
- Locations
- 🇩🇰
Odense University Hospital, Odense, Fyn, Denmark
Interest in Clonidine in Association With Levobupivacaine Performing a Pudendal Block in Proctological Surgery.
- Conditions
- Interventions
- First Posted Date
- 2020-08-28
- Last Posted Date
- 2020-09-17
- Lead Sponsor
- Centre Hospitalier Universitaire Saint Pierre
- Target Recruit Count
- 30
- Registration Number
- NCT04530903
- Locations
- 🇧🇪
University Hospital Saint-Pierre, Brussels, Belgium
Sympathetic Regulation of Large Artery Stiffness in Humans With ISH
- Conditions
- Interventions
- First Posted Date
- 2020-06-09
- Last Posted Date
- 2024-04-19
- Lead Sponsor
- University of Iowa
- Target Recruit Count
- 78
- Registration Number
- NCT04423627
- Locations
- 🇺🇸
Amy Stroud, Iowa City, Iowa, United States
🇺🇸University of Iowa, Iowa City, Iowa, United States
The Effect of Buccal Infiltration Administration of Clonidine on the Success Rate of Inferior Alveolar Nerve Block
- Conditions
- Interventions
- First Posted Date
- 2019-12-04
- Last Posted Date
- 2023-04-10
- Lead Sponsor
- University of California, San Francisco
- Registration Number
- NCT04186299
Concepts for Analgosedation During Placement of Regional Anaesthesia Before Operations.
- Conditions
- Interventions
- First Posted Date
- 2019-07-19
- Last Posted Date
- 2019-10-21
- Lead Sponsor
- Medical University of Graz
- Target Recruit Count
- 50
- Registration Number
- NCT04026074
- Locations
- 🇦🇹
Medical University Hospital LKH Graz, Graz, Austria
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.