Clonidine
- Generic Name
- Clonidine
- Brand Names
- Catapres, Catapres-TTS, Catapres-tts-1, Duraclon, Kapvay, Nexiclon XR
- Drug Type
- Small Molecule
- Chemical Formula
- C9H9Cl2N3
- CAS Number
- 4205-90-7
- Unique Ingredient Identifier
- MN3L5RMN02
- Background
Clonidine is an imidazole derivate that acts as an agonist of alpha-2 adrenoceptors. This activity is useful for the treatment of hypertension, severe pain, and ADHD.
Clonidine was granted FDA approval on 3 September 1974.
- Indication
Clonidine tablets and transdermal systems are indicated for the treatment of hypertension alone or in combination with other medications. A clonidine injection is indicated for use with opiates in the treatment of severe cancer pain where opiates alone are insufficient. An extended release tablet of clonidine is indicated for the treatment of ADHD either alo...
- Associated Conditions
- Attention Deficit Hyperactivity Disorder (ADHD), Defiant Disorder, Oppositional, Gilles de la Tourette's Syndrome, Hot Flashes, Human Growth Hormone Deficiency, Hypertension, Opioid Withdrawal (Disorder), Pheochromocytoma, Postherpetic Neuralgia, Sialorrhea caused by clozapine, Diabetic diarrhea, Methadone withdrawal, Severe Cancer pain
- Associated Therapies
- Smoking, Cessation
Buprenorphine in the Emergency Department
- Conditions
- Interventions
- First Posted Date
- 2017-06-02
- Last Posted Date
- 2017-06-02
- Lead Sponsor
- St. Joseph's Health Centre Toronto
- Target Recruit Count
- 26
- Registration Number
- NCT03174067
Dexmedetomidine Versus Clonidine in TAP Block
- Conditions
- Interventions
- First Posted Date
- 2017-05-16
- Last Posted Date
- 2020-08-20
- Lead Sponsor
- Assiut University
- Target Recruit Count
- 90
- Registration Number
- NCT03155646
- Locations
- 🇪🇬
Assiut University Hospital, Assiut, Egypt
Matão Controlling Hypertension (MatCH Study): Rationale and Design
- Conditions
- Interventions
- First Posted Date
- 2017-05-10
- Last Posted Date
- 2017-11-21
- Target Recruit Count
- 15000
- Registration Number
- NCT03147092
OFA - Opioid Free Anesthesia
- Conditions
- Interventions
- First Posted Date
- 2017-04-21
- Last Posted Date
- 2017-04-21
- Lead Sponsor
- University of Parma
- Target Recruit Count
- 64
- Registration Number
- NCT03124082
- Locations
- 🇮🇹
University Hospital, Parma, Italy
The Effect of Local Anesthetic and Clonidine on the Cutaneous Silent Period During Spinal Anesthesia
- Conditions
- Interventions
- First Posted Date
- 2017-04-20
- Last Posted Date
- 2024-12-06
- Lead Sponsor
- University Hospital Dubrava
- Target Recruit Count
- 60
- Registration Number
- NCT03121261
- Locations
- 🇭🇷
Clinical Hospital Dubrava, Zagreb, Croatia
Treatment of Neonatal Abstinence Syndrome With Clonidine Versus Morphine as Primary Therapy
- Conditions
- Interventions
- First Posted Date
- 2017-03-27
- Last Posted Date
- 2024-10-11
- Lead Sponsor
- The Cooper Health System
- Target Recruit Count
- 69
- Registration Number
- NCT03092011
- Locations
- 🇺🇸
Cooper University Hospital, Camden, New Jersey, United States
Addition of Clonidine to Ropivacaine in Adductor Canal Block
- Conditions
- Interventions
- First Posted Date
- 2017-02-17
- Last Posted Date
- 2018-05-03
- Lead Sponsor
- University of Vermont
- Target Recruit Count
- 80
- Registration Number
- NCT03057015
- Locations
- 🇺🇸
University of Vermont Medical Center, Burlington, Vermont, United States
Pregabalin for Opiate Withdrawal Syndrome
- Conditions
- Interventions
- First Posted Date
- 2017-01-11
- Last Posted Date
- 2020-04-07
- Target Recruit Count
- 100
- Registration Number
- NCT03017430
- Locations
- 🇷🇺
St.-Petersburg Bekhterev Reserach Psychoneurological Institute, St.-Petersburg, Russian Federation
Intrathecal Clonidine Addiction for Combined Spinal Epidural Analgesia During Labor
- First Posted Date
- 2017-01-11
- Last Posted Date
- 2017-04-27
- Lead Sponsor
- San Giovanni Calibita Fatebenefratelli Hospital
- Target Recruit Count
- 268
- Registration Number
- NCT03018171
- Locations
- 🇮🇹
San Giovanni Calibita Fatebenefratelli, Tiberine Island, Hospital, Rome, Italy
Clonidine for Sleep Disturbances in Children With Autism Spectrum Disorder
- Conditions
- Interventions
- First Posted Date
- 2016-06-24
- Last Posted Date
- 2017-02-02
- Lead Sponsor
- Ohio State University
- Registration Number
- NCT02812368
- Locations
- 🇺🇸
Ohio State University Nisonger Center, Columbus, Ohio, United States
Drug Development Updates
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