Amitriptyline
- Generic Name
- Amitriptyline
- Brand Names
- Elavil
- Drug Type
- Small Molecule
- Chemical Formula
- C20H23N
- CAS Number
- 50-48-6
- Unique Ingredient Identifier
- 1806D8D52K
- Background
Amitriptyline is a tricyclic antidepressant that has been used to treat depression for decades. ELAVIL, a previously approved branded product of amitriptyline, was first approved by the FDA in 1961. Amitriptyline has been investigated in the treatment of pain-related conditions, attributed to its analgesic properties.
- Indication
This drug in indicated for the following conditions :
Major depressive disorder in adults
Management of neuropathic pain in adults
Prophylactic treatment of chronic tension-type headache (CTTH) in adults
Prophylactic treatment of migraine in adults
...
- Associated Conditions
- Anorexia Nervosa (AN), Attention Deficit Hyperactivity Disorder (ADHD), Bulimia Nervosa, Depression, Depression Acute, Diabetic Neuropathies, Insomnia, Irritable Bowel Syndrome (IBS), Major Depressive Disorder (MDD), Migraine, Moderate Depression, Neuropathic Pain, Nocturnal Enuresis, Severe Depression, Sleep disorders and disturbances, Tension Headache, Moderate Agitation, Moderate Anxiety, Severe Anxiety, Severe agitation
- Associated Therapies
- -
Amitriptyline for Repetitive Behaviors in Autism Spectrum Disorders
- Conditions
- Interventions
- First Posted Date
- 2021-01-26
- Last Posted Date
- 2023-11-07
- Lead Sponsor
- University of Missouri, Kansas City
- Target Recruit Count
- 30
- Registration Number
- NCT04725383
- Locations
- 🇺🇸
University Health Behavioral Health Canvas Building, Kansas City, Missouri, United States
Physiology of GERD and Treatment Response
- First Posted Date
- 2020-03-03
- Last Posted Date
- 2023-03-28
- Lead Sponsor
- University of California, Davis
- Target Recruit Count
- 7
- Registration Number
- NCT04292470
- Locations
- 🇺🇸
University of California Davis Medical Center, Sacramento, California, United States
Amitriptyline in Treating Hypoglycemia
- Conditions
- Interventions
- First Posted Date
- 2018-07-19
- Last Posted Date
- 2019-07-22
- Lead Sponsor
- University of Utah
- Target Recruit Count
- 2
- Registration Number
- NCT03591458
- Locations
- 🇺🇸
University of Utah, Salt Lake City, Utah, United States
Preemptive Analgesia With Amitryptyline for Prevention of Pain in Women After Hysterectomy
- First Posted Date
- 2018-07-16
- Last Posted Date
- 2018-11-26
- Lead Sponsor
- University of Campinas, Brazil
- Target Recruit Count
- 150
- Registration Number
- NCT03587025
- Locations
- 🇧🇷
FCM CG - Faculdade de Ciências Médicas de Campina Grande, Campina Grande, Paraíba, Brazil
Mind and Body Approaches to Pain Reduction in Youth With Migraine
- First Posted Date
- 2018-03-21
- Last Posted Date
- 2024-02-07
- Lead Sponsor
- Children's Hospital Medical Center, Cincinnati
- Target Recruit Count
- 215
- Registration Number
- NCT03472092
- Locations
- 🇺🇸
Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States
Treatment of Neuropathic Pain in Leprosy
- Conditions
- Interventions
- First Posted Date
- 2017-10-27
- Last Posted Date
- 2022-02-23
- Lead Sponsor
- University of Sao Paulo
- Target Recruit Count
- 102
- Registration Number
- NCT03324035
- Locations
- 🇧🇷
Hospital Das Clínicas da Faculdade de Medicina da USP, São Paulo, SP, Brazil
Physical Therapy as Adjuvant Treatment of Vulvodynia: a Randomized Controled Trial
- First Posted Date
- 2016-08-18
- Last Posted Date
- 2016-08-18
- Lead Sponsor
- University of Campinas, Brazil
- Target Recruit Count
- 58
- Registration Number
- NCT02871661
- Locations
- 🇧🇷
Unicamp, Campinas, Sao Paulo, Brazil
Muscle Soreness and Stiffness in Patients With Chronic or Frequent Episodic Tension Type Headache.
- First Posted Date
- 2016-04-21
- Last Posted Date
- 2019-02-27
- Lead Sponsor
- Danish Headache Center
- Target Recruit Count
- 46
- Registration Number
- NCT02746250
- Locations
- 🇩🇰
Danish Headache center, Glostrup, Denmark
Colonoscopy-related Pain Predicts the Treatment Response of Amitriptyline in Patients With Irritable Bowel Syndrome
- Conditions
- First Posted Date
- 2015-12-23
- Last Posted Date
- 2015-12-24
- Lead Sponsor
- Samsung Medical Center
- Target Recruit Count
- 118
- Registration Number
- NCT02638870
- Locations
- 🇰🇷
Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea, Republic of
Treatment of Chronic Laryngitis With Amitriptyline
- First Posted Date
- 2015-09-17
- Last Posted Date
- 2021-10-29
- Lead Sponsor
- Boston Medical Center
- Target Recruit Count
- 6
- Registration Number
- NCT02552225
- Locations
- 🇺🇸
Boston Medical Center, Boston, Massachusetts, United States
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.