Tamsulosin

Generic Name
Tamsulosin
Brand Names
Flomax, Jalyn
Drug Type
Small Molecule
Chemical Formula
C20H28N2O5S
CAS Number
106133-20-4
Unique Ingredient Identifier
G3P28OML5I
Background

Tamsulosin is a selective alpha-1A and alpha-1B adrenoceptor antagonist that exerts its greatest effect in the prostate and bladder, where these receptors are most common. It is indicated for the treatment of signs and symptoms of benign prostatic hypertrophy. Antagonism of these receptors leads to relaxation of smooth muscle in the prostate and detrusor mus...

Indication

Tamsulosin is indicated for the treatment of signs and symptoms of benign prostatic hyperplasia.

Tamsulosin is also used off label for the treatment of ureteral stones, prostatitis, and female voiding dysfunction.

Associated Conditions
Benign Prostatic Hyperplasia (BPH), Benign Prostatic Hypertrophy, Bladder Outlet Obstruction, Ureteral Calculus
Associated Therapies
-

Comparative Efficacy of Dutasteride Plus Tamulosin With Lifestyle Advice Versus Watchful Waiting Plus Lifestyle Advice in the Management of Treatment naïve Men With Moderately Symptomatic Benign Prostatic Hyperplasia and Prostate Enlargement

First Posted Date
2011-02-11
Last Posted Date
2018-08-20
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
742
Registration Number
NCT01294592
Locations
🇬🇧

GSK Investigational Site, High Heaton, Newcastle Upon Tyne, United Kingdom

Effects of the Use of Adjuvant Drugs After Extracorporeal Shockwave Lithotripsy (ESWL) in Renal Calculus

Phase 3
Conditions
Interventions
First Posted Date
2010-10-06
Last Posted Date
2010-10-06
Lead Sponsor
University of Sao Paulo General Hospital
Target Recruit Count
136
Registration Number
NCT01215708
Locations
🇧🇷

Clinics Hospital of University of Sao Paulo, Sao Paulo, Brazil

Efficacy And Safety Study Of Naftopidil to Patients Treatment With LUTS

Phase 3
Withdrawn
Conditions
Interventions
First Posted Date
2010-09-16
Last Posted Date
2023-02-08
Lead Sponsor
Apsen Farmaceutica S.A.
Registration Number
NCT01203371
Locations
🇧🇷

Hospital das Clínicas da Faculdade de Medicina da USP, São Paulo, Brazil

Tamsulosin Hydrochloride 0.4 mg Capsules Under Fasting Conditions

Phase 1
Completed
Conditions
Interventions
First Posted Date
2010-06-23
Last Posted Date
2010-06-23
Lead Sponsor
Teva Pharmaceuticals USA
Target Recruit Count
32
Registration Number
NCT01149746
Locations
🇨🇦

Pharma Medica Research Inc., Toronto, Ontario, Canada

Tamsulosin Hydrochloride 0.4 mg Capsules Under Fed Conditions

Phase 1
Completed
Conditions
Interventions
First Posted Date
2010-06-23
Last Posted Date
2024-08-20
Lead Sponsor
Teva Pharmaceuticals USA
Target Recruit Count
32
Registration Number
NCT01149733
Locations
🇨🇦

Pharma Medica Research Inc., Toronto, Ontario, Canada

Medication Effects on Periurethral Sensation,Urethral Sphincter Activity and Pressure Flow Parameters

First Posted Date
2009-12-09
Last Posted Date
2012-06-08
Lead Sponsor
University of Alabama at Birmingham
Target Recruit Count
56
Registration Number
NCT01028014
Locations
🇺🇸

University of Alabama at Birmingham, The Kirklin Clinic, Birmingham, Alabama, United States

A Study of Tadalafil in Men With Benign Prostatic Hyperplasia

First Posted Date
2009-09-02
Last Posted Date
2012-03-12
Lead Sponsor
Eli Lilly and Company
Target Recruit Count
511
Registration Number
NCT00970632
Locations
🇵🇱

For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician., Warsaw, Poland

Clinical Effect and Safety of Tamsulosin 0.4mg in Patients With LUTS/BPH Refractory to Tamsulosin 0.2mg

First Posted Date
2009-08-07
Last Posted Date
2011-11-01
Lead Sponsor
Samsung Medical Center
Target Recruit Count
220
Registration Number
NCT00954889
Locations
🇰🇷

Department of Urology, Samsung Medical Center, Seoul, Korea, Republic of

Efficacy Study of Tamsulosin and Tolterodine Treatment for Chronic Prostatitis

First Posted Date
2009-06-04
Last Posted Date
2009-06-05
Lead Sponsor
Chongqing Medical University
Target Recruit Count
30
Registration Number
NCT00913315
Locations
🇨🇳

Department of Urology, the First Affiliated Hospital of Chongqing Medical University, Chongqing, Chongqing, China

Multinational Study to Evaluate Tadalafil in Asian Men With Signs and Symptoms of Benign Prostatic Hyperplasia

First Posted Date
2009-03-13
Last Posted Date
2011-06-28
Lead Sponsor
Eli Lilly and Company
Target Recruit Count
612
Registration Number
NCT00861757
Locations
🇨🇳

For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician., Tao-Yuan, Taiwan

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