Tamsulosin

Generic Name
Tamsulosin
Brand Names
Flomax, Jalyn
Drug Type
Small Molecule
Chemical Formula
C20H28N2O5S
CAS Number
106133-20-4
Unique Ingredient Identifier
G3P28OML5I
Background

Tamsulosin is a selective alpha-1A and alpha-1B adrenoceptor antagonist that exerts its greatest effect in the prostate and bladder, where these receptors are most common. It is indicated for the treatment of signs and symptoms of benign prostatic hypertrophy. Antagonism of these receptors leads to relaxation of smooth muscle in the prostate and detrusor mus...

Indication

Tamsulosin is indicated for the treatment of signs and symptoms of benign prostatic hyperplasia.

Tamsulosin is also used off label for the treatment of ureteral stones, prostatitis, and female voiding dysfunction.

Associated Conditions
Benign Prostatic Hyperplasia (BPH), Benign Prostatic Hypertrophy, Bladder Outlet Obstruction, Ureteral Calculus
Associated Therapies
-

Comparison of Tamsulosin and Solifenacin in Treatment of Ureteral Stent Symptoms

First Posted Date
2013-06-19
Last Posted Date
2015-11-25
Lead Sponsor
Mansoura University
Target Recruit Count
131
Registration Number
NCT01880619
Locations
🇪🇬

Urology and Nephrology Center, Mansoura, Egypt

Treatment of Symptoms After Stent Placement for Urinary Tract Obstruction

Phase 4
Completed
Conditions
Interventions
First Posted Date
2012-12-05
Last Posted Date
2019-07-10
Lead Sponsor
University of Wisconsin, Madison
Target Recruit Count
181
Registration Number
NCT01741454
Locations
🇺🇸

University of Wisconsin, Madison, Wisconsin, United States

Advanced Benefits of Alpha-blocker Monotherapy on Lower Urinary Tracts Symptoms(LUTS) Patients

First Posted Date
2012-11-29
Last Posted Date
2014-05-14
Lead Sponsor
Seoul National University Hospital
Target Recruit Count
545
Registration Number
NCT01736033
Locations
🇰🇷

Chungbuk National University Hospital, Cheongju, Chungbuk, Korea, Republic of

🇰🇷

Eulji General Hospital, Seoul, Korea, Republic of

🇰🇷

Hallym University Sacred Heart Hospital, Anyang, Gyeoggi, Korea, Republic of

and more 8 locations

An 8-week, Open-label, Uncontrolled Study of Tamsulosin 0.4mg in Men With Bothersome Urinary Symptoms

Phase 2
Completed
Conditions
Interventions
First Posted Date
2012-11-14
Last Posted Date
2020-03-27
Lead Sponsor
Boehringer Ingelheim
Target Recruit Count
689
Registration Number
NCT01726270
Locations
🇺🇸

Boehringer Ingelheim Investigational Site, Richmond, Virginia, United States

Bioequivalence - Duodart Against Avodart & Omnic

First Posted Date
2012-08-06
Last Posted Date
2017-06-20
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
35
Registration Number
NCT01657851
Locations
🇷🇺

GSK Investigational Site, Reutov, Moscow Region, Russian Federation

Use of Tamsulosin to Reduce the Incidence and Duration of Postoperative Urinary Retention Following Spine Surgery

First Posted Date
2012-04-02
Last Posted Date
2024-05-30
Lead Sponsor
Mayo Clinic
Target Recruit Count
90
Registration Number
NCT01568918
Locations
🇺🇸

Mayo Clinic in Rochester, Rochester, Minnesota, United States

Differential Effect of Silodosin Versus Tamsulosin on Stone Clearance After Extra-corporeal Shock Wave Lithotripsy

First Posted Date
2012-03-22
Last Posted Date
2017-02-17
Lead Sponsor
Albert Einstein Healthcare Network
Registration Number
NCT01560091
Locations
🇺🇸

Albert Einstein Healthcare Network, Philadelphia, Pennsylvania, United States

A Study to Evaluate Cardiovascular Interactions Between Mirabegron and Tamsulosin

First Posted Date
2011-12-12
Last Posted Date
2013-12-09
Lead Sponsor
Astellas Pharma Inc
Target Recruit Count
48
Registration Number
NCT01489696
Locations
🇬🇧

Covance CRU Ltd, Leeds, United Kingdom

Pilot Trial Of Urinary Nerve Growth Factor (NGF) As Biomarker for Male Lower Urinary Tract Symptoms

First Posted Date
2011-10-24
Last Posted Date
2018-04-02
Lead Sponsor
Timothy Boone, MD, PhD
Target Recruit Count
10
Registration Number
NCT01457573
Locations
🇺🇸

The Methodist Hospital System, Houston, Texas, United States

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