Methylphenidate
- Generic Name
- Methylphenidate
- Brand Names
- Adhansia, Aptensio, Biphentin, Concerta, Cotempla, Daytrana, Foquest, Jornay, Metadate, Methylin, Quillichew, Quillivant, Relexxii, Ritalin
- Drug Type
- Small Molecule
- Chemical Formula
- C14H19NO2
- CAS Number
- 113-45-1
- Unique Ingredient Identifier
- 207ZZ9QZ49
- Background
Methylphenidate is a central nervous system stimulant used most commonly in the treatment of Attention-Deficit/Hyperactivity Disorder (ADHD) and for narcolepsy. Also known as the marketed products Ritalin, Concerta, or Biphentin, methylphenidate is used with other treatment modalities (psychological, educational, cognitive behaviour therapy, etc) to improve ...
- Indication
Methylphenidate is indicated for the treatment of Attention Deficit Hyperactivity Disorder (ADHD) in patients 6 years of age and older and for the treatment of narcolepsy.
- Associated Conditions
- Attention Deficit Hyperactivity Disorder (ADHD), Narcolepsy
- Associated Therapies
- -
A Study of the Effectiveness and Safety of Prolonged-release Methylphenidate Hydrochloride in Adult Patients With Attention Deficit/Hyperactivity Disorder.
- Conditions
- First Posted Date
- 2005-10-30
- Last Posted Date
- 2011-05-17
- Lead Sponsor
- Janssen Pharmaceutica N.V., Belgium
- Target Recruit Count
- 402
- Registration Number
- NCT00246220
CONCERTA® (Methylphenidate Hydrochloride) as add-on Therapy in the Treatment of Adult Major Depressive Disorder.
- Conditions
- First Posted Date
- 2005-10-30
- Last Posted Date
- 2011-05-17
- Lead Sponsor
- Janssen-Ortho Inc., Canada
- Target Recruit Count
- 145
- Registration Number
- NCT00246233
Medication Strategies for Treating Aggressive Behavior in Youth With Attention Deficit Hyperactivity Disorder
- Conditions
- First Posted Date
- 2005-09-28
- Last Posted Date
- 2013-10-31
- Lead Sponsor
- Stony Brook University
- Target Recruit Count
- 40
- Registration Number
- NCT00228046
- Locations
- 🇺🇸
Stony Brook University Hospital, Stony Brook, New York, United States
🇺🇸Long Island Jewish Medical Center / Schneider Children's Hospital, New Hyde Park, New York, United States
Evaluation of Efficiency of Ritalin in Multiple Sclerosis (MS) Patients
- First Posted Date
- 2005-09-22
- Last Posted Date
- 2007-01-05
- Lead Sponsor
- Sheba Medical Center
- Target Recruit Count
- 80
- Registration Number
- NCT00220493
- Locations
- 🇮🇱
Multiple Sclerosis Center, Ramat Gan, Israel
Methylphenidate and Driving Ability in Adult Patients With Attention-Deficit Hyperactivity Disorder
- Conditions
- First Posted Date
- 2005-09-22
- Last Posted Date
- 2006-03-01
- Lead Sponsor
- Utrecht Institute for Pharmaceutical Sciences
- Target Recruit Count
- 18
- Registration Number
- NCT00223561
- Locations
- 🇳🇱
Utrecht Institute for Pharmaceutical Sciences, Utrecht, Netherlands
Treatment of Orthostatic Hypotension in Autonomic Failure
- Conditions
- Interventions
- Drug: AtomoxetineDrug: placeboDrug: AcarboseDevice: inflatable abdominal binder (sham)Drug: Pyridostigmine BromideDrug: YohimbineDrug: Midodrine HClDrug: ModafinilDrug: OctreotideOther: water intakeDrug: Diphenhydramine HydrochlorideDrug: Ranitidine HCLDrug: TranylcypromineDrug: Ergotamine/ CaffeineDrug: CelecoxibDrug: PseudoephedrineDrug: MethylphenidateDrug: IndomethacinDrug: IbuprofenDrug: Oxymetazoline 0.05% nasal solutionDietary Supplement: BovrilDrug: AcetazolamideDrug: Rivastigmine tartrateDrug: Carbidopa/levodopaDevice: Inflatable abdominal binder
- First Posted Date
- 2005-09-22
- Last Posted Date
- 2017-01-18
- Lead Sponsor
- Vanderbilt University
- Target Recruit Count
- 389
- Registration Number
- NCT00223691
- Locations
- 🇺🇸
Vanderbilt University, Nashville, Tennessee, United States
Stimulant Versus Nonstimulant Medication for Attention Deficit Hyperactivity Disorder in Children
- Conditions
- Interventions
- First Posted Date
- 2005-09-16
- Last Posted Date
- 2018-06-06
- Lead Sponsor
- Icahn School of Medicine at Mount Sinai
- Target Recruit Count
- 232
- Registration Number
- NCT00183391
- Locations
- 🇺🇸
University of Illinois, Chicago - Institute for Juvenile Research, Chicago, Illinois, United States
🇺🇸Icahn School of Medicine at Mount Sinai, New York, New York, United States
NF1-Attention: Study of Children With Neurofibromatosis Type 1 Treated by Methylphenidate
- Conditions
- First Posted Date
- 2005-09-15
- Last Posted Date
- 2011-01-27
- Lead Sponsor
- Hospices Civils de Lyon
- Target Recruit Count
- 80
- Registration Number
- NCT00169611
- Locations
- 🇫🇷
Laurence LION-FRANCOIS, Lyon, France
Efficacy, Safety and Tolerability of SPD485 in Children Aged 6-12 Diagnosed With ADHD
- Conditions
- Interventions
- First Posted Date
- 2005-09-09
- Last Posted Date
- 2015-07-09
- Lead Sponsor
- Noven Therapeutics
- Target Recruit Count
- 128
- Registration Number
- NCT00151970
Psychostimulants for Fatigue in Prostate Cancer
- Conditions
- First Posted Date
- 2005-08-30
- Last Posted Date
- 2007-12-10
- Lead Sponsor
- Memorial Sloan Kettering Cancer Center
- Target Recruit Count
- 120
- Registration Number
- NCT00138138
- Locations
- 🇺🇸
Memorial Sloan-Kettering Cancer Center, New York, New York, United States
Drug Development Updates
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