Prednisone
- Generic Name
- Prednisone
- Brand Names
- Deltasone, Rayos, Winpred
- Drug Type
- Small Molecule
- Chemical Formula
- C21H26O5
- CAS Number
- 53-03-2
- Unique Ingredient Identifier
- VB0R961HZT
- Background
A synthetic anti-inflammatory glucocorticoid derived from cortisone. It is biologically inert and converted to prednisolone in the liver.
Prednisone was granted FDA approval on 21 February 1955.
- Indication
Prednisone is indicated as an anti-inflammatory or immunosuppressive drug for allergic, dermatologic, gastrointestinal, hematologic, ophthalmologic, nervous system, renal, respiratory, rheumatologic, infectious, endocrine, or neoplastic conditions as well as in organ transplant.
- Associated Conditions
- Acne Vulgaris, Acute Exacerbation of Chronic Obstructive Pulmonary Disease, Acute Gouty Arthritis, Acute Leukemia, Aggressive Lymphoma, Allergic Bronchopulmonary Aspergillosis, Allergic Conjunctivitis (AC), Allergic Rhinitis (AR), Allergic corneal marginal ulcers, Alveolitis, Extrinsic Allergic, Ankylosing Spondylitis (AS), Aspiration Pneumonitis, Asthma, Atopic Dermatitis, Autoimmune Hepatitis, Bell's Palsy, Berylliosis, Bullous dermatitis herpetiformis, Chorioretinitis, Congenital Adrenal Hyperplasia (CAH), Congenital Hypoplastic Anemia, Contact Dermatitis, Disseminated tuberculosis, Drug hypersensitivity reaction, Edema of the cerebrum, Epicondylitis, Erythroblastopenia, Giant Cell Arteritis (GCA), Hypercalcemia of Malignancy, Idiopathic Pulmonary Fibrosis (IPF), Immune Thrombocytopenia (ITP), Iridocyclitis, Iritis, Keratitis, Leukemias, Loeffler's syndrome, Lymphoma, Meningitis caused by Mycobacterium Tuberculosis, Metastatic Castration-Resistant Prostate Cancer (mCRPC), Mycosis Fungoides (MF), Ocular Inflammation, Ophthalmia, Sympathetic, Optic Neuritis, Pain caused by Herpes zoster, Pemphigus, Pericarditis, Pneumocystis Jirovecii Pneumonia, Polymyalgia Rheumatica (PMR), Polymyositis, Posterior Uveitis, Primary adrenocortical insufficiency, Psoriatic Arthritis, Pure Red Cell Aplasia, Regional Enteritis, Relapsing Polychondritis, Rheumatoid Arthritis, Rheumatoid Arthritis, Juvenile, Secondary adrenocortical insufficiency, Secondary thrombocytopenia, Serum Sickness, Severe Seborrheic Dermatitis, Sjogren's Syndrome (SS), Solid Organ Transplant Rejection, Stevens-Johnson Syndrome, Systemic Lupus Erythematosus, Takayasu Arteritis, Thyroid Eye Disease, Thyroiditis, Thyrotoxicosis, Trichinosis, Ulcerative Colitis, Uveitis, Vasculitis, Acquired immune hemolytic anemia, Acute Bursitis, Acute Crohn's Disease (CD), Acute Multiple sclerosis exacerbation, Acute rheumatic carditis, Anterior eye segment inflammation, Exfoliative erythroderma, Fulminating Tuberculosis, Idiopathic Bronchiolitis obliterans with organizing pneumonia, Idiopathic eosinophilic pneumonias, Non-suppurative Thyroiditis, Severe Psoriasis, Subacute Bursitis, Symptomatic Sarcoidosis, Synovitis of osteoarthritis, Systemic Dermatomyositis, Varicella-zoster virus acute retinal necrosis
- Associated Therapies
- Palliative Treatment
Chidamide Combined With PECM in Relapsed or Refractory Peripheral T-cell Lymphoma (PTCL)
- Conditions
- Interventions
- First Posted Date
- 2017-10-26
- Last Posted Date
- 2017-10-26
- Lead Sponsor
- Sun Yat-sen University
- Target Recruit Count
- 102
- Registration Number
- NCT03321890
- Locations
- 🇨🇳
Department of Medical Oncology,Sun Yat-Sen University Cancer Center, Guangzhou, Guangdong, China
Budesonide for Immunosuppression After Liver Transplantation to Reduce Side Effects
- Conditions
- Interventions
- First Posted Date
- 2017-10-19
- Last Posted Date
- 2019-09-23
- Lead Sponsor
- Montefiore Medical Center
- Registration Number
- NCT03315052
Efficacy of Rituximab in Comparison to Continued Corticosteroid Treatment in Idiopathic Nephrotic Syndrome
- Conditions
- Interventions
- First Posted Date
- 2017-10-02
- Last Posted Date
- 2018-08-27
- Lead Sponsor
- Radboud University Medical Center
- Target Recruit Count
- 40
- Registration Number
- NCT03298698
- Locations
- 🇳🇱
Radboud University Medical Center, Nijmegen, Netherlands
Study of Safety and Efficacy of Avadomide (CC-122) Combined With RCHOP for Newly-diagnosed DLBCL With Poor Risk Factors
- Conditions
- Interventions
- First Posted Date
- 2017-09-14
- Last Posted Date
- 2021-04-29
- Lead Sponsor
- Celgene
- Target Recruit Count
- 35
- Registration Number
- NCT03283202
- Locations
- 🇪🇸
Hospital Universitario Virgen Del Rocio, Sevilla, Spain
🇺🇸Moffitt Cancer Center, Tampa, Florida, United States
🇺🇸Washington University, Saint Louis, Missouri, United States
Apalutamide and Gonadotropin-Releasing Hormone Analog With or Without Abiraterone Acetate in Treating Participants With Prostate Cancer
- Conditions
- Interventions
- First Posted Date
- 2017-09-12
- Last Posted Date
- 2022-08-10
- Lead Sponsor
- M.D. Anderson Cancer Center
- Target Recruit Count
- 86
- Registration Number
- NCT03279250
- Locations
- 🇺🇸
M D Anderson Cancer Center, Houston, Texas, United States
A Study Comparing the Efficacy and Safety of Polatuzumab Vedotin With Rituximab-Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Rituximab-Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (R-CHOP) in Participants With Diffuse Large B-Cell Lymphoma
- Conditions
- Interventions
- First Posted Date
- 2017-09-07
- Last Posted Date
- 2024-10-04
- Lead Sponsor
- Hoffmann-La Roche
- Target Recruit Count
- 1000
- Registration Number
- NCT03274492
- Locations
- 🇺🇸
University of Alabama at Birmingham, Birmingham, Alabama, United States
🇺🇸Southern Cancer Center, Daphne, Alabama, United States
🇺🇸City of Hope, Duarte, California, United States
Short Term Effect of Glucocorticoids on Brown Adipose Tissue Thermogenesis in Humans
- First Posted Date
- 2017-09-01
- Last Posted Date
- 2019-06-05
- Lead Sponsor
- University Hospital, Basel, Switzerland
- Target Recruit Count
- 16
- Registration Number
- NCT03269747
- Locations
- 🇨🇭
University Hospital Basel, Department of Endocrinology, Basel, BS, Switzerland
Obinutuzumab With or Without Umbralisib, Lenalidomide, or Combination Chemotherapy in Treating Patients With Relapsed or Refractory Grade I-IIIa Follicular Lymphoma
- Conditions
- Interventions
- Procedure: BiopsyDrug: Bendamustine HydrochlorideProcedure: Biospecimen CollectionProcedure: Computed TomographyProcedure: EchocardiographyProcedure: Multigated Acquisition ScanDrug: LenalidomideDrug: CyclophosphamideBiological: ObinutuzumabDrug: Doxorubicin HydrochlorideProcedure: Positron Emission TomographyDrug: UmbralisibDrug: PrednisoneDrug: Vincristine Sulfate
- First Posted Date
- 2017-09-01
- Last Posted Date
- 2024-12-27
- Lead Sponsor
- National Cancer Institute (NCI)
- Target Recruit Count
- 95
- Registration Number
- NCT03269669
- Locations
- 🇺🇸
Longmont United Hospital, Longmont, Colorado, United States
🇺🇸Rocky Mountain Cancer Centers-Longmont, Longmont, Colorado, United States
🇺🇸Banner McKee Medical Center, Loveland, Colorado, United States
High Dose Oral Steroids in Sudden Sensorineural Hearing Loss
- Conditions
- Interventions
- First Posted Date
- 2017-08-21
- Last Posted Date
- 2024-10-11
- Lead Sponsor
- University of Colorado, Denver
- Target Recruit Count
- 4
- Registration Number
- NCT03255473
- Locations
- 🇺🇸
University of Colorado Anschutz Medical Campus, Aurora, Colorado, United States
Study of Entospletinib (ENTO) in Newly Diagnosed DLBCL Patients With aaIPI>=1 Treated by Chemiotherapy
- Conditions
- Interventions
- First Posted Date
- 2017-07-21
- Last Posted Date
- 2020-09-02
- Lead Sponsor
- The Lymphoma Academic Research Organisation
- Target Recruit Count
- 25
- Registration Number
- NCT03225924
- Locations
- 🇧🇪
UCL Namur, Yvoir, Belgium
🇧🇪Institut Jules Bordet, Bruxelles, Belgium
🇧🇪Az Groeninge, Kortrijk, Belgium
Drug Development Updates
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