Prednisone
- Generic Name
- Prednisone
- Brand Names
- Deltasone, Rayos, Winpred
- Drug Type
- Small Molecule
- Chemical Formula
- C21H26O5
- CAS Number
- 53-03-2
- Unique Ingredient Identifier
- VB0R961HZT
- Background
A synthetic anti-inflammatory glucocorticoid derived from cortisone. It is biologically inert and converted to prednisolone in the liver.
Prednisone was granted FDA approval on 21 February 1955.
- Indication
Prednisone is indicated as an anti-inflammatory or immunosuppressive drug for allergic, dermatologic, gastrointestinal, hematologic, ophthalmologic, nervous system, renal, respiratory, rheumatologic, infectious, endocrine, or neoplastic conditions as well as in organ transplant.
- Associated Conditions
- Acne Vulgaris, Acute Exacerbation of Chronic Obstructive Pulmonary Disease, Acute Gouty Arthritis, Acute Leukemia, Aggressive Lymphoma, Allergic Bronchopulmonary Aspergillosis, Allergic Conjunctivitis (AC), Allergic Rhinitis (AR), Allergic corneal marginal ulcers, Alveolitis, Extrinsic Allergic, Ankylosing Spondylitis (AS), Aspiration Pneumonitis, Asthma, Atopic Dermatitis, Autoimmune Hepatitis, Bell's Palsy, Berylliosis, Bullous dermatitis herpetiformis, Chorioretinitis, Congenital Adrenal Hyperplasia (CAH), Congenital Hypoplastic Anemia, Contact Dermatitis, Disseminated tuberculosis, Drug hypersensitivity reaction, Edema of the cerebrum, Epicondylitis, Erythroblastopenia, Giant Cell Arteritis (GCA), Hypercalcemia of Malignancy, Idiopathic Pulmonary Fibrosis (IPF), Immune Thrombocytopenia (ITP), Iridocyclitis, Iritis, Keratitis, Leukemias, Loeffler's syndrome, Lymphoma, Meningitis caused by Mycobacterium Tuberculosis, Metastatic Castration-Resistant Prostate Cancer (mCRPC), Mycosis Fungoides (MF), Ocular Inflammation, Ophthalmia, Sympathetic, Optic Neuritis, Pain caused by Herpes zoster, Pemphigus, Pericarditis, Pneumocystis Jirovecii Pneumonia, Polymyalgia Rheumatica (PMR), Polymyositis, Posterior Uveitis, Primary adrenocortical insufficiency, Psoriatic Arthritis, Pure Red Cell Aplasia, Regional Enteritis, Relapsing Polychondritis, Rheumatoid Arthritis, Rheumatoid Arthritis, Juvenile, Secondary adrenocortical insufficiency, Secondary thrombocytopenia, Serum Sickness, Severe Seborrheic Dermatitis, Sjogren's Syndrome (SS), Solid Organ Transplant Rejection, Stevens-Johnson Syndrome, Systemic Lupus Erythematosus, Takayasu Arteritis, Thyroid Eye Disease, Thyroiditis, Thyrotoxicosis, Trichinosis, Ulcerative Colitis, Uveitis, Vasculitis, Acquired immune hemolytic anemia, Acute Bursitis, Acute Crohn's Disease (CD), Acute Multiple sclerosis exacerbation, Acute rheumatic carditis, Anterior eye segment inflammation, Exfoliative erythroderma, Fulminating Tuberculosis, Idiopathic Bronchiolitis obliterans with organizing pneumonia, Idiopathic eosinophilic pneumonias, Non-suppurative Thyroiditis, Severe Psoriasis, Subacute Bursitis, Symptomatic Sarcoidosis, Synovitis of osteoarthritis, Systemic Dermatomyositis, Varicella-zoster virus acute retinal necrosis
- Associated Therapies
- Palliative Treatment
Treating Young Patients With Newly Diagnosed, Low Stage, Lymphocyte Predominant Hodgkin Disease
- Conditions
- Interventions
- First Posted Date
- 2005-04-06
- Last Posted Date
- 2023-09-11
- Lead Sponsor
- Children's Oncology Group
- Target Recruit Count
- 188
- Registration Number
- NCT00107198
- Locations
- 🇵🇷
San Jorge Children's Hospital, San Juan, Puerto Rico
🇺🇸Rocky Mountain Hospital for Children-Presbyterian Saint Luke's Medical Center, Denver, Colorado, United States
🇺🇸Tulane University School of Medicine, New Orleans, Louisiana, United States
Rituximab for the Treatment of Wegener's Granulomatosis and Microscopic Polyangiitis
- Conditions
- Interventions
- First Posted Date
- 2005-02-25
- Last Posted Date
- 2017-04-21
- Target Recruit Count
- 197
- Registration Number
- NCT00104299
- Locations
- 🇺🇸
Hospital for Special Surgery, New York, New York, United States
🇺🇸University of Alabama, Birmingham, Alabama, United States
🇺🇸Johns Hopkins University, Baltimore, Maryland, United States
Universal Granulocyte Macrophage-colony Stimulating Factor (GM-CSF)-Producing and GM.CD40L for Autologous Tumor Vaccine in Mantle Cell Lymphoma
- Conditions
- Interventions
- First Posted Date
- 2005-01-10
- Last Posted Date
- 2023-08-22
- Target Recruit Count
- 43
- Registration Number
- NCT00101101
- Locations
- 🇺🇸
H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States
Rituximab and Combination Chemotherapy in Treating Older Patients With Diffuse Large B-Cell Lymphoma
- First Posted Date
- 2005-01-10
- Last Posted Date
- 2020-10-19
- Lead Sponsor
- M.D. Anderson Cancer Center
- Target Recruit Count
- 80
- Registration Number
- NCT00101010
- Locations
- 🇺🇸
CCOP - Grand Rapids, Grand Rapids, Michigan, United States
🇺🇸Hembree Mercy Cancer Center at St. Edward Mercy Medical Center, Fort Smith, Arkansas, United States
🇺🇸CCOP - Kalamazoo, Kalamazoo, Michigan, United States
Chemoimmunotherapy With Epratuzumab in Relapsed Acute Lymphoblastic Leukemia (ALL)
- Conditions
- Interventions
- Drug: L-asparaginaseDrug: doxorubicin hydrochlorideDrug: therapeutic hydrocortisoneDrug: vincristine sulfateBiological: epratuzumabDrug: cytarabineDrug: prednisoneDrug: pegaspargaseDrug: dexrazoxane hydrochlorideDrug: methotrexateDrug: etoposideDrug: cyclophosphamideDrug: leucovorin calciumBiological: filgrastim
- First Posted Date
- 2004-12-09
- Last Posted Date
- 2017-12-12
- Lead Sponsor
- Children's Oncology Group
- Target Recruit Count
- 134
- Registration Number
- NCT00098839
- Locations
- 🇺🇸
Indiana University Medical Center, Indianapolis, Indiana, United States
🇺🇸M D Anderson Cancer Center, Houston, Texas, United States
🇺🇸Seattle Children's Hospital, Seattle, Washington, United States
Sudden Deafness Treatment Trial
- Conditions
- Interventions
- First Posted Date
- 2004-11-24
- Last Posted Date
- 2017-04-04
- Lead Sponsor
- Massachusetts Eye and Ear Infirmary
- Target Recruit Count
- 255
- Registration Number
- NCT00097448
- Locations
- 🇺🇸
Johns Hopkins University, Baltimore, Maryland, United States
🇺🇸Michigan Ear Institute, Farmington Hills, Michigan, United States
🇺🇸Washington University School of Medicine, St. Louis, Missouri, United States
Combination Chemotherapy in Treating Patients With AIDS-Related Lymphoma
- Conditions
- Interventions
- Biological: Bleomycin SulfateBiological: FilgrastimDrug: CyclophosphamideDrug: CytarabineDrug: CisplatinDrug: Doxorubicin Hydrochloride (DOX)Drug: FluorouracilDrug: Leucovorin calciumDrug: EtoposideDrug: PentamidineDrug: PrednisoneDrug: IfosfamideDrug: Trimethoprim-SulfamethoxazoleDrug: MethotrexateDrug: Vincristine SulfateDrug: MethylprednisoloneDrug: Zidovudine (AZT)Radiation: Radiation Therapy
- First Posted Date
- 2004-10-05
- Last Posted Date
- 2012-07-30
- Lead Sponsor
- M.D. Anderson Cancer Center
- Target Recruit Count
- 46
- Registration Number
- NCT00002524
- Locations
- 🇺🇸
MD Anderson Cancer Center Orlando, Orlando, Florida, United States
🇺🇸University of Texas - MD Anderson Cancer Center, Houston, Texas, United States
Virotherapy and Natural History Study of KHSV-Associated Multricentric Castleman s Disease With Correlates of Disease Activity
- Conditions
- Interventions
- First Posted Date
- 2004-09-22
- Last Posted Date
- 2024-12-19
- Lead Sponsor
- National Cancer Institute (NCI)
- Target Recruit Count
- 75
- Registration Number
- NCT00092222
- Locations
- 🇺🇸
National Institutes of Health Clinical Center, Bethesda, Maryland, United States
Combination Chemotherapy in Treating Children With Newly Diagnosed Acute Lymphoblastic Leukemia
- Conditions
- Interventions
- Drug: asparaginaseDrug: cyclophosphamideDrug: cytarabineDrug: daunorubicin hydrochlorideDrug: dexamethasoneDrug: doxorubicin hydrochlorideDrug: mercaptopurineDrug: methotrexateDrug: pegaspargaseDrug: prednisoneDrug: therapeutic hydrocortisoneDrug: thioguanineDrug: vincristine sulfateRadiation: low-LET cobalt-60 gamma ray therapyRadiation: low-LET photon therapy
- First Posted Date
- 2004-09-01
- Last Posted Date
- 2017-02-09
- Lead Sponsor
- Children's Oncology Group
- Target Recruit Count
- 1970
- Registration Number
- NCT00002744
- Locations
- 🇺🇸
Jonsson Comprehensive Cancer Center, UCLA, Los Angeles, California, United States
🇺🇸Children's Hospital of Columbus, Columbus, Ohio, United States
🇺🇸Children's Hospital and Medical Center - Seattle, Seattle, Washington, United States
Combination Chemotherapy in Treating Children With Relapsed Acute Lymphocytic Leukemia
- Conditions
- Locations
- 🇦🇷
Grupo Argentino de Tratamiento de la Leucemia Aguda, Buenos Aires, Argentina
Drug Development Updates
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