Pivmecillinam
- Generic Name
- Pivmecillinam
- Brand Names
- -
- Drug Type
- Small Molecule
- Chemical Formula
- C21H33N3O5S
- CAS Number
- 32886-97-8
- Unique Ingredient Identifier
- 1WAM1OQ30B
- Background
Pivmecillinam is a mecillinam prodrug, a pivaloyloxymethyl ester of amdinocillin that is well absorbed orally, but broken down to amdinocillin in the intestinal mucosa. It is active against gram-negative organisms and used as for amdinocillin. [PubChem]
- Indication
Used to treat infections due to mecillinam-sensitive organisms such as urinary tract infections, salmonellosis and typhoid fever.
- Associated Conditions
- Urinary tract infection caused by E. coli, Urinary tract infection caused by enterobacteria, Urinary tract infection caused by klebsiella, Urinary tract infection caused by proteus
- Associated Therapies
- -
Clinical Trial Testing Whether Targeted Antibiotic Prophylaxis Can Reduce Infections After Cystectomy Compared to Empiric Prophylaxis
- Conditions
- Interventions
- First Posted Date
- 2024-11-29
- Last Posted Date
- 2024-12-16
- Lead Sponsor
- Rigshospitalet, Denmark
- Target Recruit Count
- 248
- Registration Number
- NCT06709196
- Locations
- 🇩🇰
Department of Urology, Aalborg University Hospital, Aalborg, Denmark
🇩🇰Department of Urology, Aarhus University Hospital, Aarhus, Denmark
🇩🇰Department of Urology, Rigshospitalet, Copenhagen, Denmark
Clinical Effectiveness and Bacteriological Eradication of 4 Short-course Antibiotics for Uncomplicated UTIs in Women.
- Conditions
- Interventions
- First Posted Date
- 2021-07-13
- Last Posted Date
- 2023-12-11
- Target Recruit Count
- 1000
- Registration Number
- NCT04959331
- Locations
- 🇪🇸
Calatayud Center, Calatayud, Aragón, Spain
🇪🇸Parque Goya Health Center, Zaragoza, Aragón, Spain
🇪🇸Montblanc Center, Montblanc, Catalonia, Spain
Treating Pyelonephritis an Urosepsis With Pivmecillinam
- First Posted Date
- 2017-09-13
- Last Posted Date
- 2020-04-22
- Lead Sponsor
- Sykehuset i Vestfold HF
- Target Recruit Count
- 53
- Registration Number
- NCT03282006
- Locations
- 🇳🇴
Vestfold Hospital Trust, Tønsberg, Vestfold, Norway
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.