Methylprednisolone hemisuccinate

Generic Name
Methylprednisolone hemisuccinate
Brand Names
Solu-medrol
Drug Type
Small Molecule
Chemical Formula
C26H34O8
CAS Number
2921-57-5
Unique Ingredient Identifier
5GMR90S4KN
Background

A water-soluble ester of methylprednisolone used for cardiac, allergic, and hypoxic emergencies.

Associated Conditions
Acute Gouty Arthritis, Ankylosing Spondylitis (AS), Berylliosis, Congenital Adrenal Hyperplasia (CAH), Congenital Hypoplastic Anemia, Dermatitis bullous, Dermatomyositis (DM), Edema of the cerebrum, Hypercalcemia of Malignancy, Immune Thrombocytopenia (ITP), Leukemias, Lymphoma, Multiple sclerosis exacerbation, Mycosis Fungoides (MF), Ophthalmia, Sympathetic, Pemphigus, Polymyositis, Primary adrenocortical insufficiency, Psoriatic Arthritis, Pure Red Cell Aplasia, Refractory Uveitis, Regional Enteritis, Rheumatoid Arthritis, Secondary adrenocortical insufficiency, Secondary thrombocytopenia, Stevens-Johnson Syndrome, Systemic Lupus Erythematosus, Temporal Arteritis, Trichinosis, Tuberculous Meningitis, Ulcerative Colitis, Acquired immune hemolytic anemia, Acute rheumatic carditis, Disseminated Pulmonary Tuberculosis (TB), Exfoliative erythroderma, Fulminating Pulmonary Tuberculosis, Idiopathic eosinophilic pneumonias, Non-suppurative Thyroiditis, Severe Allergic Reactions, Symptomatic Sarcoidosis
Associated Therapies
Palliative Treatment
Clinical Trials
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First Posted Date
2020-06-18
Last Posted Date
2024-06-13
Lead Sponsor
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Target Recruit Count
1
Registration Number
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Locations
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Johns Hopkins University/Sidney Kimmel Cancer Center, Baltimore, Maryland, United States

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Mercy Health Mercy Campus, Muskegon, Michigan, United States

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Bronson Battle Creek, Battle Creek, Michigan, United States

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Phase 1/2 Clinical Trial of PR001 in Infants With Type 2 Gaucher Disease (PROVIDE)

First Posted Date
2020-06-02
Last Posted Date
2024-03-21
Lead Sponsor
Prevail Therapeutics
Target Recruit Count
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Registration Number
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Locations
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Manchester Centre for Genomic Medicine, 6th Floor, St Mary's Hospital, Oxford Road, Manchester, United Kingdom

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UCSF Benioff Children's Hospital, 5700 Martin Luther King Jr Way, Oakland, California, United States

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University of Minnesota Masonic Children's Hospital, 2450 Riverside Avenue, Minneapolis, Minnesota, United States

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Phase 1/2 Clinical Trial of LY3884963 in Patients With Frontotemporal Dementia With Progranulin Mutations (FTD-GRN)

First Posted Date
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Last Posted Date
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Target Recruit Count
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Registration Number
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Locations
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UZ Leuven, Neurologie Herestraat 49, Leuven, Belgium

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k2 Medical Research-Maitland, Maitland, Florida, United States

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AP-HM Hôpital de La Timone, Saint-Pierre, Marseille, France

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Early Short Course Corticosteroids in COVID-19

Completed
Conditions
COVID
Pneumonia, Viral
Interventions
Drug: Methylprednisolone
First Posted Date
2020-05-05
Last Posted Date
2020-05-05
Lead Sponsor
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Target Recruit Count
250
Registration Number
NCT04374071
Locations
🇺🇸

Henry Ford Hospital, Detroit, Michigan, United States

The Fleming [FMTVDM] Directed CoVid-19 Treatment Protocol

First Posted Date
2020-04-16
Last Posted Date
2020-11-12
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Registration Number
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FHHI-OI-Camelot; QME, Los Angeles, California, United States

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First Posted Date
2020-04-14
Last Posted Date
2020-04-14
Lead Sponsor
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Registration Number
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University Malaya Medical Centre, Kuala Lumpur, Malaysia

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First Posted Date
2020-04-10
Last Posted Date
2020-04-10
Lead Sponsor
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Target Recruit Count
84
Registration Number
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Locations
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Hospital Universitari de Bellvitge, L'Hospitalet de Llobregat, Barcelona, Spain

Methylprednisolone for Patients With COVID-19 Severe Acute Respiratory Syndrome

First Posted Date
2020-03-26
Last Posted Date
2020-06-24
Lead Sponsor
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173
Registration Number
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Locations
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Marco Confalonieri, Trieste, TS, Italy

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First Posted Date
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Efficacy and Safety of Corticosteroids in COVID-19

Not Applicable
Completed
Conditions
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COVID-19
Interventions
Drug: Methylprednisolone
First Posted Date
2020-02-18
Last Posted Date
2020-05-11
Lead Sponsor
Beijing Chao Yang Hospital
Target Recruit Count
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Registration Number
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Locations
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Beijing YouAn Hospital, Beijing, China

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the first peopel hospital of Xiangyang, Xiangyang, China

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Tianyou Hospital Affiliated to Wuhan University of science and technology, Wuhan, China

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