Methylprednisolone hemisuccinate
- Generic Name
- Methylprednisolone hemisuccinate
- Brand Names
- Solu-medrol
- Drug Type
- Small Molecule
- Chemical Formula
- C26H34O8
- CAS Number
- 2921-57-5
- Unique Ingredient Identifier
- 5GMR90S4KN
- Background
A water-soluble ester of methylprednisolone used for cardiac, allergic, and hypoxic emergencies.
- Associated Conditions
- Acute Gouty Arthritis, Ankylosing Spondylitis (AS), Berylliosis, Congenital Adrenal Hyperplasia (CAH), Congenital Hypoplastic Anemia, Dermatitis bullous, Dermatomyositis (DM), Edema of the cerebrum, Hypercalcemia of Malignancy, Immune Thrombocytopenia (ITP), Leukemias, Lymphoma, Multiple sclerosis exacerbation, Mycosis Fungoides (MF), Ophthalmia, Sympathetic, Pemphigus, Polymyositis, Primary adrenocortical insufficiency, Psoriatic Arthritis, Pure Red Cell Aplasia, Refractory Uveitis, Regional Enteritis, Rheumatoid Arthritis, Secondary adrenocortical insufficiency, Secondary thrombocytopenia, Stevens-Johnson Syndrome, Systemic Lupus Erythematosus, Temporal Arteritis, Trichinosis, Tuberculous Meningitis, Ulcerative Colitis, Acquired immune hemolytic anemia, Acute rheumatic carditis, Disseminated Pulmonary Tuberculosis (TB), Exfoliative erythroderma, Fulminating Pulmonary Tuberculosis, Idiopathic eosinophilic pneumonias, Non-suppurative Thyroiditis, Severe Allergic Reactions, Symptomatic Sarcoidosis
- Associated Therapies
- Palliative Treatment
Glucocorticoid Therapy in Coronavirus Disease COVID-19 Patients
- Conditions
- Interventions
- First Posted Date
- 2021-03-03
- Last Posted Date
- 2022-06-14
- Target Recruit Count
- 127
- Registration Number
- NCT04780581
- Locations
- 🇪🇸
Complejo Asistencial Universitario de León, León, Spain
🇪🇸Hospital Clínico Universitario de Valladolid, Valladolid, Spain
🇪🇸Complejo Asistencial Universitario de Salamanca, Salamanca, Spain
Non-inferiority Study of Ocrelizumab and Rituximab in Active Multiple Sclerosis
- Conditions
- Interventions
- First Posted Date
- 2020-12-30
- Last Posted Date
- 2024-05-16
- Lead Sponsor
- Rigshospitalet, Denmark
- Target Recruit Count
- 600
- Registration Number
- NCT04688788
- Locations
- 🇩🇰
Department of Neurology, Herlev Hospital, Herlev, Denmark
🇩🇰Department of Neurology, Aalborg University Hospital, Aalborg, Denmark
🇩🇰Department of Neurology, Aarhus University Hospital, Aarhus, Denmark
Assessment of the Efficacy of Medrol Dose Pack for Acute Post-Concussive Headaches
- Conditions
- First Posted Date
- 2020-12-28
- Last Posted Date
- 2024-11-11
- Lead Sponsor
- Northwell Health
- Target Recruit Count
- 25
- Registration Number
- NCT04685772
- Locations
- 🇺🇸
Northwell Health - North Shore University Hospital, Manhasset, New York, United States
Study of Relugolix in Men With Metastatic Castration-Sensitive Prostate Cancer or Non-Metastatic or Metastatic Castration-Resistant Prostate Cancer
- First Posted Date
- 2020-12-14
- Last Posted Date
- 2024-12-18
- Lead Sponsor
- Sumitomo Pharma Switzerland GmbH
- Target Recruit Count
- 48
- Registration Number
- NCT04666129
- Locations
- 🇺🇸
Clinical Research Alliance, Inc., Westbury, New York, United States
🇺🇸Arkansas Urology, Little Rock, Arkansas, United States
🇺🇸Alliance Urology, Greensboro, North Carolina, United States
Methylprednisolone vs. Dexamethasone in COVID-19 Pneumonia (MEDEAS RCT)
- Conditions
- Interventions
- First Posted Date
- 2020-11-19
- Last Posted Date
- 2022-05-17
- Lead Sponsor
- University of Trieste
- Target Recruit Count
- 690
- Registration Number
- NCT04636671
- Locations
- 🇮🇹
Marco Confalonieri, Trieste, TS, Italy
A Study Evaluating the Efficacy and Safety of Obinutuzumab in Participants With Primary Membranous Nephropathy
- Conditions
- Interventions
- First Posted Date
- 2020-11-16
- Last Posted Date
- 2024-08-22
- Lead Sponsor
- Hoffmann-La Roche
- Target Recruit Count
- 140
- Registration Number
- NCT04629248
- Locations
- 🇺🇦
Regional Clinical Hospital n.a I.I. Mechnicov, Dnipropetrovsk, Ukraine
🇺🇦Ternopil University Hospital, Ternopil, Kherson Governorate, Ukraine
🇺🇸Nephrotex Research Group, Dallas, Texas, United States
Steroid Treatment After Resuscitated Out-of-Hospital Cardiac Arrest
- First Posted Date
- 2020-11-12
- Last Posted Date
- 2023-03-29
- Lead Sponsor
- Christian Hassager
- Target Recruit Count
- 158
- Registration Number
- NCT04624776
- Locations
- 🇩🇰
Rigshospitalet, Copenhagen, Denmark
🇩🇰Gentofte Hospital, Gentofte, Denmark
Association Between the Effect of Glucocorticoid Pulse Therapy on Neuromyelitis Optica (NMO) and Gene Polymorphism
- Conditions
- Interventions
- First Posted Date
- 2020-10-23
- Last Posted Date
- 2020-10-23
- Lead Sponsor
- Beijing Tongren Hospital
- Target Recruit Count
- 350
- Registration Number
- NCT04601142
- Locations
- 🇨🇳
Beijing Tongren Hospital, Beijing, China
A Study to Evaluate the Efficacy, Safety and Pharmacokinetics of a Higher Dose of Ocrelizumab in Adults With Primary Progressive Multiple Sclerosis (PPMS)
- Conditions
- Interventions
- First Posted Date
- 2020-09-16
- Last Posted Date
- 2024-03-15
- Lead Sponsor
- Hoffmann-La Roche
- Target Recruit Count
- 769
- Registration Number
- NCT04548999
- Locations
- 🇺🇸
University of California Irvine, Irvine, California, United States
🇺🇸Massachusetts General Hospital., Boston, Massachusetts, United States
🇵🇱Neurologiczny Niepubliczny ZOZ Centrum Leczenia SM Osrodek Bada? Klinicznych, Plewiska, Poland
A Study to Evaluate the Efficacy, Safety and Pharmacokinetics of a Higher Dose of Ocrelizumab in Adults With Relapsing Multiple Sclerosis (RMS)
- Conditions
- Interventions
- First Posted Date
- 2020-09-10
- Last Posted Date
- 2024-07-01
- Lead Sponsor
- Hoffmann-La Roche
- Target Recruit Count
- 864
- Registration Number
- NCT04544436
- Locations
- 🇺🇸
Maine Medical Center, Scarborough, Maine, United States
🇵🇱Neurocentrum Bydgoszcz sp. z o.o, Bydgoszcz, Poland
🇵🇱Indywidualna Praktyka Lekarska Prof. Dr Hab. N. Med. Konrad Rejdak., Lublin, Poland
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.