Methylprednisolone hemisuccinate

Generic Name: Methylprednisolone hemisuccinate

Brand Names: Solu-medrol

Drug Type: Small Molecule

Chemical Formula: C_₂₆H_₃₄O_₈

CAS Number: 2921-57-5

Unique Ingredient Identifier: 5GMR90S4KN

Background: A water-soluble ester of methylprednisolone used for cardiac, allergic, and hypoxic emergencies.

Associated Conditions: Acute Gouty Arthritis, Ankylosing Spondylitis (AS), Berylliosis, Congenital Adrenal Hyperplasia (CAH), Congenital Hypoplastic Anemia, Dermatitis bullous, Dermatomyositis (DM), Edema of the cerebrum, Hypercalcemia of Malignancy, Immune Thrombocytopenia (ITP), Leukemias, Lymphoma, Multiple sclerosis exacerbation, Mycosis Fungoides (MF), Ophthalmia, Sympathetic, Pemphigus, Polymyositis, Primary adrenocortical insufficiency, Psoriatic Arthritis, Pure Red Cell Aplasia, Refractory Uveitis, Regional Enteritis, Rheumatoid Arthritis, Secondary adrenocortical insufficiency, Secondary thrombocytopenia, Stevens-Johnson Syndrome, Systemic Lupus Erythematosus, Temporal Arteritis, Trichinosis, Tuberculous Meningitis, Ulcerative Colitis, Acquired immune hemolytic anemia, Acute rheumatic carditis, Disseminated Pulmonary Tuberculosis (TB), Exfoliative erythroderma, Fulminating Pulmonary Tuberculosis, Idiopathic eosinophilic pneumonias, Non-suppurative Thyroiditis, Severe Allergic Reactions, Symptomatic Sarcoidosis

Associated Therapies: Palliative Treatment

Clinical Trials

Methylprednisolone Treatment of Friedreich Ataxia

Early Phase 1

Completed

Conditions: Friedreich Ataxia

Interventions: Drug: Methylprednisolone

First Posted Date: 2015-04-23

Last Posted Date: 2021-03-25

Lead Sponsor: Children's Hospital of Philadelphia

Target Recruit Count: 11

Registration Number: NCT02424435

Locations: 🇺🇸
Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States

Cannabidiol for the Treatment of Severe (Grades III/IV) Acute Graft-versus-host Disease

Phase 2

Conditions: Acute-graft-versus-host Disease

Interventions: Drug: Cannabidiol
Drug: Methylprednisolone
Drug: Calcineurin inhibitor

First Posted Date: 2015-03-19

Last Posted Date: 2015-03-19

Lead Sponsor: moshe yeshurun

Target Recruit Count: 10

Registration Number: NCT02392780

Locations: 🇮🇱
Davidof Cancer Center, Beilinson hospital, Rabin medical center, Petach Tikva, Israel

Steroids in Fulminant Hepatitis A in the Pediatric Age Group

Phase 4

Completed

Conditions: Fulminant Hepatic Failure

Interventions: Drug: prednisolone
Drug: methylprednisolone

First Posted Date: 2015-03-03

Last Posted Date: 2018-12-17

Lead Sponsor: National Liver Institute, Egypt

Target Recruit Count: 33

Registration Number: NCT02375867

Locations: 🇪🇬
National Liver Institute, Menoufia, Egypt

Study Evaluating the Safety and Efficacy of KTE-C19 in Adult Participants With Refractory Aggressive Non-Hodgkin Lymphoma

First Posted Date: 2015-01-28

Last Posted Date: 2024-06-04

Lead Sponsor: Kite, A Gilead Company

Target Recruit Count: 307

Registration Number: NCT02348216

Locations: 🇺🇸
Hackensack University Medical Center, Hackensack, New Jersey, United States
🇺🇸
University of California Los Angeles (UCLA), Santa Monica, California, United States
🇨🇦
Princess Margaret, Toronto, Ontario, Canada

and more 33 locations