Methylprednisolone hemisuccinate

Generic Name
Methylprednisolone hemisuccinate
Brand Names
Solu-medrol
Drug Type
Small Molecule
Chemical Formula
C26H34O8
CAS Number
2921-57-5
Unique Ingredient Identifier
5GMR90S4KN
Background

A water-soluble ester of methylprednisolone used for cardiac, allergic, and hypoxic emergencies.

Associated Conditions
Acute Gouty Arthritis, Ankylosing Spondylitis (AS), Berylliosis, Congenital Adrenal Hyperplasia (CAH), Congenital Hypoplastic Anemia, Dermatitis bullous, Dermatomyositis (DM), Edema of the cerebrum, Hypercalcemia of Malignancy, Immune Thrombocytopenia (ITP), Leukemias, Lymphoma, Multiple sclerosis exacerbation, Mycosis Fungoides (MF), Ophthalmia, Sympathetic, Pemphigus, Polymyositis, Primary adrenocortical insufficiency, Psoriatic Arthritis, Pure Red Cell Aplasia, Refractory Uveitis, Regional Enteritis, Rheumatoid Arthritis, Secondary adrenocortical insufficiency, Secondary thrombocytopenia, Stevens-Johnson Syndrome, Systemic Lupus Erythematosus, Temporal Arteritis, Trichinosis, Tuberculous Meningitis, Ulcerative Colitis, Acquired immune hemolytic anemia, Acute rheumatic carditis, Disseminated Pulmonary Tuberculosis (TB), Exfoliative erythroderma, Fulminating Pulmonary Tuberculosis, Idiopathic eosinophilic pneumonias, Non-suppurative Thyroiditis, Severe Allergic Reactions, Symptomatic Sarcoidosis
Associated Therapies
Palliative Treatment

Methylprednisolone for Children With Severe Mycoplasma Pneumoniae Pneumonia (MCMP)

Not Applicable
Completed
Conditions
Interventions
First Posted Date
2014-12-01
Last Posted Date
2021-01-08
Lead Sponsor
Beijing Children's Hospital
Target Recruit Count
424
Registration Number
NCT02303587
Locations
🇨🇳

Beijing Children's Hospital, Capital Medical University, Beijing, Beijing, China

Weekly 70 mg/m2 Carfilzomib for Multiple Myeloma Patients Refractory to 27 mg/m2 Carfilzomib

First Posted Date
2014-11-19
Last Posted Date
2023-11-01
Lead Sponsor
Oncotherapeutics
Target Recruit Count
45
Registration Number
NCT02294357
Locations
🇺🇸

James R Berenson, MD, Inc., West Hollywood, California, United States

🇺🇸

Blood & Cancer Center of East Texas, Tyler, Texas, United States

🇺🇸

California Cancer Associates for Research & Excellence (cCARE), Encinitas, California, United States

and more 4 locations

Stem Cell Transplantation for Stiff Person Syndrome (SPS)

First Posted Date
2014-11-04
Last Posted Date
2021-01-27
Lead Sponsor
Northwestern University
Target Recruit Count
23
Registration Number
NCT02282514
Locations
🇺🇸

Northwestern University, Chicago, Illinois, United States

Rituximab and Belimumab for Lupus Nephritis

First Posted Date
2014-10-09
Last Posted Date
2020-12-01
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
43
Registration Number
NCT02260934
Locations
🇺🇸

University of Alabama, Birmingham, Birmingham, Alabama, United States

🇺🇸

UCLA Medical Center: Division of Rheumatology, Los Angeles, California, United States

🇺🇸

Colorado Kidney Care, Denver, Colorado, United States

and more 12 locations

Effect of Anti-Inflammatory Agents on Biological Responses to Endotoxin Inhalation in Healthy Subjects

Early Phase 1
Completed
Conditions
Interventions
First Posted Date
2014-09-30
Last Posted Date
2014-09-30
Lead Sponsor
Brugmann University Hospital
Target Recruit Count
51
Registration Number
NCT02252809

Maternal Epidural Steroids and Hyperthemia

First Posted Date
2014-08-08
Last Posted Date
2017-08-29
Lead Sponsor
Medical University of South Carolina
Target Recruit Count
135
Registration Number
NCT02212210
Locations
🇺🇸

Medical University of South Carolina, Charleston, South Carolina, United States

Management Of The Infusion-Associated Reactions In RRMS Patients Treated With LEMTRADA

First Posted Date
2014-07-31
Last Posted Date
2016-06-09
Lead Sponsor
Genzyme, a Sanofi Company
Target Recruit Count
58
Registration Number
NCT02205489
Locations
🇧🇪

Investigational Site Number 056001, Brussels, Belgium

🇳🇱

Investigational Site Number 528001, Breda, Netherlands

🇳🇱

Investigational Site Number 528002, Rotterdam, Netherlands

and more 17 locations
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