Methylprednisolone hemisuccinate
- Generic Name
- Methylprednisolone hemisuccinate
- Brand Names
- Solu-medrol
- Drug Type
- Small Molecule
- Chemical Formula
- C26H34O8
- CAS Number
- 2921-57-5
- Unique Ingredient Identifier
- 5GMR90S4KN
- Background
A water-soluble ester of methylprednisolone used for cardiac, allergic, and hypoxic emergencies.
- Associated Conditions
- Acute Gouty Arthritis, Ankylosing Spondylitis (AS), Berylliosis, Congenital Adrenal Hyperplasia (CAH), Congenital Hypoplastic Anemia, Dermatitis bullous, Dermatomyositis (DM), Edema of the cerebrum, Hypercalcemia of Malignancy, Immune Thrombocytopenia (ITP), Leukemias, Lymphoma, Multiple sclerosis exacerbation, Mycosis Fungoides (MF), Ophthalmia, Sympathetic, Pemphigus, Polymyositis, Primary adrenocortical insufficiency, Psoriatic Arthritis, Pure Red Cell Aplasia, Refractory Uveitis, Regional Enteritis, Rheumatoid Arthritis, Secondary adrenocortical insufficiency, Secondary thrombocytopenia, Stevens-Johnson Syndrome, Systemic Lupus Erythematosus, Temporal Arteritis, Trichinosis, Tuberculous Meningitis, Ulcerative Colitis, Acquired immune hemolytic anemia, Acute rheumatic carditis, Disseminated Pulmonary Tuberculosis (TB), Exfoliative erythroderma, Fulminating Pulmonary Tuberculosis, Idiopathic eosinophilic pneumonias, Non-suppurative Thyroiditis, Severe Allergic Reactions, Symptomatic Sarcoidosis
- Associated Therapies
- Palliative Treatment
A Study to Evaluate the Safety and Efficacy of Obinutuzumab Compared With Placebo in Participants With Lupus Nephritis (LN)
- Conditions
- Interventions
- First Posted Date
- 2015-09-15
- Last Posted Date
- 2024-08-27
- Lead Sponsor
- Hoffmann-La Roche
- Target Recruit Count
- 126
- Registration Number
- NCT02550652
- Locations
- 🇺🇸
Emory Uni ; Division of Rheumatology, Atlanta, Georgia, United States
🇺🇸Univ of California, San Diego, La Jolla, California, United States
🇺🇸Stanford University Medical Center, Palo Alto, California, United States
Effect of Methylprednisolone on Immune Signaling in Hip-arthroplasty Patients
- Conditions
- Interventions
- First Posted Date
- 2015-09-07
- Last Posted Date
- 2017-01-18
- Lead Sponsor
- Rigshospitalet, Denmark
- Target Recruit Count
- 64
- Registration Number
- NCT02542592
- Locations
- 🇩🇰
Copenhagen University Hospital, Bispebjerg, Copenhagen NV, Denmark
Methylprednisolone Combined Electric-acupuncture on Cognitive Function
- Conditions
- Interventions
- First Posted Date
- 2015-08-28
- Last Posted Date
- 2016-12-20
- Lead Sponsor
- Shengjing Hospital
- Target Recruit Count
- 80
- Registration Number
- NCT02535039
- Locations
- 🇨🇳
Shengjing hospital of China medical university, Shenyang, Liaoning, China
The Research of Standard Diagnosis and Treatment for HSPN in Children
- First Posted Date
- 2015-08-26
- Last Posted Date
- 2020-02-26
- Lead Sponsor
- Nanjing Children's Hospital
- Target Recruit Count
- 100
- Registration Number
- NCT02532777
- Locations
- 🇨🇳
Nanjing Children's Hospital, Nanjing, Jiangsu, China
Effects of Inhibiting Early Inflammation in Kidney Transplant Patients
- First Posted Date
- 2015-07-13
- Last Posted Date
- 2022-08-16
- Target Recruit Count
- 290
- Registration Number
- NCT02495077
- Locations
- 🇺🇸
University of Alabama at Birmingham, Birmingham, Alabama, United States
🇺🇸University of Maryland, Baltimore, Maryland, United States
🇺🇸University of California, Los Angeles, Los Angeles, California, United States
Non-invasive Ventilation in Reducing the Need for Intubation in Patients With Cancer and Respiratory Failure
- Conditions
- Interventions
- First Posted Date
- 2015-06-08
- Last Posted Date
- 2024-03-08
- Lead Sponsor
- M.D. Anderson Cancer Center
- Target Recruit Count
- 256
- Registration Number
- NCT02464696
- Locations
- 🇺🇸
M D Anderson Cancer Center, Houston, Texas, United States
Study of Idarubicin, Cytarabine, and Nivolumab in Patients With High-Risk Myelodysplastic Syndrome (MDS) and Acute Myeloid Leukemia (AML)
- Conditions
- Interventions
- First Posted Date
- 2015-06-08
- Last Posted Date
- 2021-10-07
- Lead Sponsor
- M.D. Anderson Cancer Center
- Target Recruit Count
- 44
- Registration Number
- NCT02464657
- Locations
- 🇺🇸
University of Texas MD Anderson Cancer Center, Houston, Texas, United States
Phase IIA Open Label Study to Evaluate Efficacy and Safety of BL-8040 Followed by (hATG), Cyclosporine and Methyprednisolone in Adult Subjects With Aplastic Anemia or Hypoplastic Myelodysplastic Syndrome
- Conditions
- Interventions
- First Posted Date
- 2015-06-04
- Last Posted Date
- 2020-12-29
- Lead Sponsor
- BioLineRx, Ltd.
- Target Recruit Count
- 11
- Registration Number
- NCT02462252
- Locations
- 🇺🇸
MD Anderson Cancer Center, Houston, Texas, United States
Effect of Methylprednisolone on Orthostatic Intolerance and Heart Rate Variability in Hip-arthroplasty Patients
- Conditions
- Interventions
- First Posted Date
- 2015-05-15
- Last Posted Date
- 2017-01-18
- Lead Sponsor
- Rigshospitalet, Denmark
- Target Recruit Count
- 64
- Registration Number
- NCT02445898
- Locations
- 🇩🇰
Copenhagen University Hospital, Bispebjerg, Copenhagen NV, Denmark
Cyclophosphamide and Hydroxychloroquine for Thrombocytopenia in SLE
- Conditions
- Interventions
- First Posted Date
- 2015-05-14
- Last Posted Date
- 2022-03-14
- Lead Sponsor
- Chinese SLE Treatment And Research Group
- Target Recruit Count
- 50
- Registration Number
- NCT02444728
- Locations
- 🇨🇳
Beijng Hospital, Beijing, China
🇨🇳the Affiliated Hospital to Bangbu Medical University, Bangbu, Anhui, China
🇨🇳Hebei Provincial Hospital, Shijiazhuang, Hebei, China
Drug Development Updates
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