Methylprednisolone hemisuccinate
- Generic Name
- Methylprednisolone hemisuccinate
- Brand Names
- Solu-medrol
- Drug Type
- Small Molecule
- Chemical Formula
- C26H34O8
- CAS Number
- 2921-57-5
- Unique Ingredient Identifier
- 5GMR90S4KN
- Background
A water-soluble ester of methylprednisolone used for cardiac, allergic, and hypoxic emergencies.
- Associated Conditions
- Acute Gouty Arthritis, Ankylosing Spondylitis (AS), Berylliosis, Congenital Adrenal Hyperplasia (CAH), Congenital Hypoplastic Anemia, Dermatitis bullous, Dermatomyositis (DM), Edema of the cerebrum, Hypercalcemia of Malignancy, Immune Thrombocytopenia (ITP), Leukemias, Lymphoma, Multiple sclerosis exacerbation, Mycosis Fungoides (MF), Ophthalmia, Sympathetic, Pemphigus, Polymyositis, Primary adrenocortical insufficiency, Psoriatic Arthritis, Pure Red Cell Aplasia, Refractory Uveitis, Regional Enteritis, Rheumatoid Arthritis, Secondary adrenocortical insufficiency, Secondary thrombocytopenia, Stevens-Johnson Syndrome, Systemic Lupus Erythematosus, Temporal Arteritis, Trichinosis, Tuberculous Meningitis, Ulcerative Colitis, Acquired immune hemolytic anemia, Acute rheumatic carditis, Disseminated Pulmonary Tuberculosis (TB), Exfoliative erythroderma, Fulminating Pulmonary Tuberculosis, Idiopathic eosinophilic pneumonias, Non-suppurative Thyroiditis, Severe Allergic Reactions, Symptomatic Sarcoidosis
- Associated Therapies
- Palliative Treatment
Prevention of Noise-induced Hearing Loss
Phase 1
Withdrawn
- Conditions
- Interventions
- First Posted Date
- 2014-01-29
- Last Posted Date
- 2017-11-06
- Lead Sponsor
- Washington University School of Medicine
- Registration Number
- NCT02049073
- Locations
- 🇺🇸
Washington University School of Medicine, Saint Louis, Missouri, United States
Safety, Pharmacokinetics and Pharmacodynamics Study With 2B3-201 in Healthy Subjects and Multiple Sclerosis(MS) Patients
Phase 1
Terminated
- Conditions
- Interventions
- First Posted Date
- 2014-01-29
- Last Posted Date
- 2015-02-06
- Lead Sponsor
- BBB-Therapeutics B.V.
- Target Recruit Count
- 47
- Registration Number
- NCT02048358
- Locations
- 🇳🇱
VUmc, PET and neurology clinical research unit, Amsterdam, Noord-Holland, Netherlands
🇳🇱Centre for Human Drug Research (CHDR), Leiden, Netherlands
Carpal Tunnel Syndrome - Randomized Clinical Trial Evaluating Effectiveness of Ultrasound in Corticosteroid Injection
Not Applicable
- Conditions
- Interventions
- First Posted Date
- 2014-01-14
- Last Posted Date
- 2014-12-16
- Lead Sponsor
- Université de Sherbrooke
- Target Recruit Count
- 50
- Registration Number
- NCT02036125
- Locations
- 🇨🇦
Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke, Quebec, Canada
BMT and High Dose Post-Transplant Cyclophosphamide for Chimerism Induction and Renal Allograft Tolerance
Phase 2
Terminated
- Conditions
- Interventions
- First Posted Date
- 2014-01-08
- Last Posted Date
- 2018-09-24
- Target Recruit Count
- 4
- Registration Number
- NCT02029638
- Locations
- 🇺🇸
Johns Hopkins University, Baltimore, Maryland, United States
A Study of MabThera/Rituxan (Rituximab) in Combination With Methotrexate in Patients With Rheumatoid Arthritis and Inadequate Response to DMARD Therapy
Phase 3
Completed
- Conditions
- Interventions
- First Posted Date
- 2013-12-10
- Last Posted Date
- 2017-08-21
- Lead Sponsor
- Hoffmann-La Roche
- Target Recruit Count
- 15
- Registration Number
- NCT02006706
OPERA Study: A Study of Two Dosing Regimens of CellCept (Mycophenolate Mofetil) in Kidney Transplant Patients.
Phase 3
Completed
- Conditions
- Interventions
- First Posted Date
- 2013-12-09
- Last Posted Date
- 2015-11-11
- Lead Sponsor
- Hoffmann-La Roche
- Target Recruit Count
- 252
- Registration Number
- NCT02005562
Preoperative Glucocorticoid Use in Major Hepatectomy
- First Posted Date
- 2013-11-28
- Last Posted Date
- 2021-04-28
- Lead Sponsor
- University of Calgary
- Target Recruit Count
- 200
- Registration Number
- NCT01997658
- Locations
- 🇨🇦
Foothills Medical Centre, Calgary, Alberta, Canada
Arthralgia of the Temporomandibular Joint. Pain Relief Following One Intra-articular Injection of Methylprednisolone
Phase 4
Completed
- Conditions
- Interventions
- First Posted Date
- 2013-11-26
- Last Posted Date
- 2017-05-19
- Lead Sponsor
- Uppsala University
- Target Recruit Count
- 56
- Registration Number
- NCT01995019
- Locations
- 🇸🇪
Orofacial pain unit, Västmanland Hospital Västerås, Västerås, Västmanland, Sweden
🇸🇪Dental specialist clinic Kaniken, Uppsala, Uppland, Sweden
🇸🇪Specialist clinic Stomatognathic physiology, Goteborg, VastraGotaland, Sweden
An Efficacy and Safety Study of Daratumumab in Patients With Multiple Myeloma Who Have Received at Least 3 Prior Lines of Therapy (Including a Proteasome Inhibitor [PI] and Immunomodulatory Drug [IMiD]) or Are Double Refractory to a PI and an IMiD
- First Posted Date
- 2013-11-15
- Last Posted Date
- 2018-06-25
- Lead Sponsor
- Janssen Research & Development, LLC
- Target Recruit Count
- 124
- Registration Number
- NCT01985126
Dexamethasone-induced Hiccup in Chemotherapy Patients Treated by Methylprednisolone Rotation
Phase 3
Completed
- Conditions
- Interventions
- First Posted Date
- 2013-11-01
- Last Posted Date
- 2017-04-28
- Lead Sponsor
- Chung-Ang University
- Target Recruit Count
- 65
- Registration Number
- NCT01974024
- Locations
- 🇰🇷
Chungang University Hospital, Dongjak-gu, Seoul, Korea, Republic of
🇰🇷Gyeongsang National University Hospital, Chiram-dong, Jinju-si, Gyeongsangnam-do, Korea, Republic of
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