Methylprednisolone hemisuccinate

Generic Name
Methylprednisolone hemisuccinate
Brand Names
Solu-medrol
Drug Type
Small Molecule
Chemical Formula
C26H34O8
CAS Number
2921-57-5
Unique Ingredient Identifier
5GMR90S4KN
Background

A water-soluble ester of methylprednisolone used for cardiac, allergic, and hypoxic emergencies.

Associated Conditions
Acute Gouty Arthritis, Ankylosing Spondylitis (AS), Berylliosis, Congenital Adrenal Hyperplasia (CAH), Congenital Hypoplastic Anemia, Dermatitis bullous, Dermatomyositis (DM), Edema of the cerebrum, Hypercalcemia of Malignancy, Immune Thrombocytopenia (ITP), Leukemias, Lymphoma, Multiple sclerosis exacerbation, Mycosis Fungoides (MF), Ophthalmia, Sympathetic, Pemphigus, Polymyositis, Primary adrenocortical insufficiency, Psoriatic Arthritis, Pure Red Cell Aplasia, Refractory Uveitis, Regional Enteritis, Rheumatoid Arthritis, Secondary adrenocortical insufficiency, Secondary thrombocytopenia, Stevens-Johnson Syndrome, Systemic Lupus Erythematosus, Temporal Arteritis, Trichinosis, Tuberculous Meningitis, Ulcerative Colitis, Acquired immune hemolytic anemia, Acute rheumatic carditis, Disseminated Pulmonary Tuberculosis (TB), Exfoliative erythroderma, Fulminating Pulmonary Tuberculosis, Idiopathic eosinophilic pneumonias, Non-suppurative Thyroiditis, Severe Allergic Reactions, Symptomatic Sarcoidosis
Associated Therapies
Palliative Treatment

Differences in Flare Reaction Incidence and Intensity Following Trigger Finger Injections

Phase 4
Completed
Conditions
Interventions
First Posted Date
2021-05-25
Last Posted Date
2023-06-23
Lead Sponsor
West Virginia University
Target Recruit Count
66
Registration Number
NCT04900220
Locations
🇺🇸

WVU Medicine University Town Center, Morgantown, West Virginia, United States

🇺🇸

Ruby Memorial Hospital or Other WVU Healthcare Site, Morgantown, West Virginia, United States

MIS-C Comparative Effectiveness Study

First Posted Date
2021-05-24
Last Posted Date
2024-09-27
Lead Sponsor
University of California, San Diego
Target Recruit Count
73
Registration Number
NCT04898231
Locations
🇺🇸

Rady Children's Hospital, San Diego, California, United States

🇺🇸

Children's Hospital Michigan, Detroit, Michigan, United States

Steroid Metabolism in Obese and Non-Obese Pediatric Patients Hospitalized for Status Asthmaticus

First Posted Date
2021-05-05
Last Posted Date
2022-07-01
Lead Sponsor
Duke University
Target Recruit Count
15
Registration Number
NCT04874610
Locations
🇺🇸

Duke University Hospital, Durham, North Carolina, United States

High Dose Steroids in Children With Stroke

Phase 3
Recruiting
Conditions
Interventions
First Posted Date
2021-05-05
Last Posted Date
2024-07-08
Lead Sponsor
Insel Gruppe AG, University Hospital Bern
Target Recruit Count
70
Registration Number
NCT04873583
Locations
🇫🇷

Hôpital Roger Salengro, CHRU de Lille, Lille, France

🇩🇪

LMU Klinikum, München, Bayern, Germany

🇩🇪

Charité-Universitätsmedizin Berlin, Berlin, Germany

and more 29 locations

TReatment for ImmUne Mediated PathopHysiology

First Posted Date
2021-04-27
Last Posted Date
2024-07-01
Lead Sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Target Recruit Count
163
Registration Number
NCT04862221
Locations
🇺🇸

Emory Children's Healthcare of Atlanta, Atlanta, Georgia, United States

🇺🇸

Cleveland Clinic Children's, Cleveland, Ohio, United States

🇺🇸

The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States

and more 19 locations

Investigation of Hospitalisation Times and Mortality According to Drug Dose in Patients Given Systemic Methylprednisolone With a Pre-diagnosis of Covid-19 Pneumonia; Retrospective Study

First Posted Date
2021-04-19
Last Posted Date
2021-04-19
Lead Sponsor
Bursa Yüksek İhtisas Education and Research Hospital
Target Recruit Count
300
Registration Number
NCT04847687
Locations
🇹🇷

Bursa Yüksek İhtisas EAH, Bursa, Eyalet/Yerleşke, Turkey

Steroids Therapy in IgA Nephropathy With Crescents

Phase 3
Conditions
Interventions
First Posted Date
2021-04-06
Last Posted Date
2021-06-04
Lead Sponsor
Sixth Affiliated Hospital, Sun Yat-sen University
Target Recruit Count
200
Registration Number
NCT04833374
Locations
🇨🇳

Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China

Oral Statins and Protection From Hearing Loss

First Posted Date
2021-04-01
Last Posted Date
2024-12-05
Lead Sponsor
Northwestern University
Target Recruit Count
100
Registration Number
NCT04826237
Locations
🇺🇸

Northwestern Memorial Hospital, Chicago, Illinois, United States

Controlling Post-extraction Complications of Impacted Mandibular Third Molar

First Posted Date
2021-03-25
Last Posted Date
2021-07-22
Lead Sponsor
Al-Azhar University
Target Recruit Count
72
Registration Number
NCT04816253
Locations
🇸🇦

Vision college, Jeddah, Saudi Arabia

Treatment Efficacy of Corticosteroids and Mycophenolate Mofetil in Patients With Immune Related Hepatitis

First Posted Date
2021-03-22
Last Posted Date
2022-12-14
Lead Sponsor
Inge Marie Svane
Target Recruit Count
60
Registration Number
NCT04810156
Locations
🇩🇰

Aarhus University Hospital, Aarhus, Denmark

🇩🇰

Odense University Hospital, Odense, Denmark

🇩🇰

Herlev University Hospital, Herlev, Copenhagen, Denmark

and more 2 locations
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