MedPath

Tebotelimab

Generic Name
Tebotelimab
Drug Type
Biotech
CAS Number
2245725-04-4
Unique Ingredient Identifier
L62556GPXB
Background

Tebotelimab is under investigation in clinical trial NCT04082364 (Combination Margetuximab, INCMGA00012, MGD013, and Chemotherapy Phase 2/3 Trial in HER2+ Gastric/gej Cancer (MAHOGANY)).

A Study to Evaluate the Safety and Efficacy of MGD013 in Patients With Melanoma

Phase 1
Terminated
Conditions
Untreated Mucosal or Acral Lentiginous Melanoma
Unresectable, Recurrent or Metastatic Melanoma
Interventions
First Posted Date
2020-12-04
Last Posted Date
2024-01-29
Lead Sponsor
Zai Lab (Shanghai) Co., Ltd.
Target Recruit Count
92
Registration Number
NCT04653038
Locations
🇨🇳

Jiangsu Province Hospital, Nanjing, Jiangsu, China

🇨🇳

Nanjing Drum Tower Hospital, Nanjing, Jiangsu, China

🇨🇳

Beijing Cancer Hospital, Beijing, Beijing, China

and more 10 locations

Combination Margetuximab, Retifanlimab, Tebotelimab, and Chemotherapy Phase 2/3 Trial in HER2+ Gastric/GEJ Cancer

Phase 2
Completed
Conditions
Gastric Cancer
Gastroesophageal Junction Cancer
HER2-positive Gastric Cancer
Interventions
First Posted Date
2019-09-09
Last Posted Date
2025-04-22
Lead Sponsor
MacroGenics
Target Recruit Count
82
Registration Number
NCT04082364
Locations
🇺🇸

Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey, United States

🇺🇸

Mayo Clinic - Scottsdale, Scottsdale, Arizona, United States

🇺🇸

City of Hope Comprehensive Cancer Center - Duarte, Duarte, California, United States

and more 70 locations

A Personalized NeoAntigen Cancer Vaccine Combined With Anti-PD-1 in Melanoma

First Posted Date
2019-08-28
Last Posted Date
2020-04-28
Lead Sponsor
Xiangya Hospital of Central South University
Target Recruit Count
30
Registration Number
NCT04072900
Locations
🇨🇳

Xiangya Hospital, Central South University, Changsha, Hunan, China

Anti-PD-1 +/- RT for MSI-H Solid Tumors

Phase 2
Withdrawn
Conditions
Microsatellite Instability High
Colorectal Cancer
Mismatch Repair Deficiency
Interventions
Combination Product: RT and Anti-PD-1
First Posted Date
2019-06-27
Last Posted Date
2021-11-30
Lead Sponsor
University of Colorado, Denver
Registration Number
NCT04001101
Locations
🇺🇸

University of Colorado Hospital, Denver, Colorado, United States

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