Vitamin C

Generic Name: Vitamin C

Brand Names: Ascor, Citranatal B-calm Kit, Concept Ob, Ferralet 90, Hematogen, Infuvite, Infuvite Pediatric, Moviprep, Mvc-fluoride, Mvi Pediatric, Natafort, Plenvu, Pregvit, Vitafol-one

Drug Type: Small Molecule

Chemical Formula: C_₆H_₈O_₆

CAS Number: 50-81-7

Unique Ingredient Identifier: PQ6CK8PD0R

Background: A six carbon compound related to glucose. It is found naturally in citrus fruits and many vegetables. Ascorbic acid is an essential nutrient in human diets, and necessary to maintain connective tissue and bone. Its biologically active form, vitamin C, functions as a reducing agent and coenzyme in several metabolic pathways. Vitamin C is considered an antioxi...

Indication: Used to treat vitamin C deficiency, scurvy, delayed wound and bone healing, urine acidification, and in general as an antioxidant. It has also been suggested to be an effective antiviral agent.

Associated Conditions: Common Cold, Deficiency, Vitamin A, Deficiency, Vitamin D, Fever, Flu caused by Influenza, Folate deficiency, Iron Deficiency (ID), Iron Deficiency Anemia (IDA), Oral bacterial infection, Scurvy, Vitamin C Deficiency, Vitamin Deficiency

Associated Therapies: Nutritional supplementation, Vitamin supplementation

Clinical Trials

Effects of Intravenous Ascorbic Acid in Patients After Cardiac Surgery on Shock Time and Microcirculation.

Not Applicable

Recruiting

Conditions: Circulation Disorder

Interventions: Drug: ascorbic acid
Drug: Placebo

First Posted Date: 2024-12-09

Last Posted Date: 2024-12-09

Lead Sponsor: Southeast University, China

Target Recruit Count: 40

Registration Number: NCT06723626

Locations: 🇨🇳
Zhongda Hospital Southeast University, Nanjing, Jiangsu, China

Transduction of Sympathetic Neural Activity in Human Obesity Without Hypertension

Recruiting

Conditions: Obesity

Interventions: Drug: ascorbic acid

First Posted Date: 2024-10-03

Last Posted Date: 2024-10-03

Lead Sponsor: University of Kansas Medical Center

Target Recruit Count: 60

Registration Number: NCT06626113

Locations: 🇺🇸
University of Kansas Medical Center, Kansas City, Kansas, United States

Role of Endothelial Function in SCI CVD Risk

Recruiting

Conditions: Spinal Cord Injuries
Cardiovascular Diseases
Endothelial Dysfunction

Interventions: Procedure: Brachial intra-arterial infusion of vasoactive and antioxidant drugs (acetylcholine, nitroprusside, ascorbic acid)
Procedure: venous occlusion plethysmography
Drug: Acetylcholine
Drug: Sodium Nitroprusside
Drug: Ascorbic acid
Procedure: venous phlebotomy

First Posted Date: 2024-06-05

Last Posted Date: 2024-08-20

Lead Sponsor: Craig Hospital

Target Recruit Count: 60

Registration Number: NCT06443151

Locations: 🇺🇸
Craig Hospital, Englewood, Colorado, United States

Effect of Vitamin C on Postoperative Pulmonary Complications After Intracranial Tumor Surgery

Phase 2

Not yet recruiting

Conditions: Humans
Ascorbic Acid
Neurosurgical Procedures
Ventilator-Induced Lung Injury
Postoperative Complications

Interventions: Drug: Ascorbic acid
Drug: Saline

First Posted Date: 2024-05-20

Last Posted Date: 2024-05-20

Lead Sponsor: Qianfoshan Hospital

Target Recruit Count: 86

Registration Number: NCT06421688

Locations: 🇨🇳
The First Affiliated Hospital of Shandong First Medical University, Jinan, Shandong, China

Combination of Vitamin C and N-Acetylcysteine to Improve Functional Outcome After Rotator Cuff Repair

Phase 4

Not yet recruiting

Conditions: Rotator Cuff Tears

Interventions: Other: placebo
Drug: Ascorbic acid
Drug: N-acetyl cysteine

First Posted Date: 2024-04-25

Last Posted Date: 2024-04-25

Lead Sponsor: Mahidol University

Target Recruit Count: 110

Registration Number: NCT06384833

Analgesic Effect of Melatonin and Vitamin C Administration, Alone or In Combination in Major Abdominal Surgery.

Not Applicable

Not yet recruiting

Conditions: Postoperative Pain

Interventions: Drug: Melatonin 10 MG
Drug: Vitamin C

First Posted Date: 2024-04-19

Last Posted Date: 2024-04-19

Lead Sponsor: Cairo University

Target Recruit Count: 60

Registration Number: NCT06374771

Locations: 🇪🇬
Faculty of Medicine - Cairo University, Cairo, Manial, Egypt

Comparison Between IPRF With Vit. C and IPRF Alone in Management of ID'Pain

Not Applicable

Completed

Conditions: TMJ Pain

Interventions: Other: Injectable platelet rich fibrin
Drug: Vitamin C

First Posted Date: 2024-04-03

Last Posted Date: 2024-11-08

Lead Sponsor: Cairo University

Target Recruit Count: 40

Registration Number: NCT06345092

Locations: 🇪🇬
Faculty of Dentistry cairo university, Cairo, Egypt

Vitamin C Deficiency in Septic Shock

Phase 4

Completed

Conditions: Septic Shock

Interventions: Drug: Ascorbic acid

First Posted Date: 2024-01-25

Last Posted Date: 2024-01-25

Lead Sponsor: Cairo University

Target Recruit Count: 150

Registration Number: NCT06224881

Locations: 🇪🇬
Cairo university, Cairo, Egypt

Blessing or Curse? Combined Vitamin Therapy in Non Viral Septic Shock.

Phase 4

Completed

Conditions: Septic Shock

Interventions: Drug: Vitamin C

First Posted Date: 2023-11-30

Last Posted Date: 2023-11-30

Lead Sponsor: University of Pecs

Target Recruit Count: 43

Registration Number: NCT06152458

Locations: 🇭🇺
Department of Anaesthesia and Intensive Therapy University of Pecs, Pécs, Baranya, Hungary

Perioperative Vitamin C to Reduce Persistent Pain After Total Knee Arthroplasty

Phase 2

Recruiting

Conditions: Knee Pain Chronic
Post Operative Pain
Chronic Pain

Interventions: Drug: Placebo
Drug: Vitamin C

First Posted Date: 2023-11-09

Last Posted Date: 2024-07-12

Lead Sponsor: University Health Network, Toronto

Target Recruit Count: 100

Registration Number: NCT06123715

Locations: 🇨🇦
Sunnybrook - Holland Centre, Toronto, Ontario, Canada
🇨🇦
Toronto Western Hospital, Toronto, Ontario, Canada
🇨🇦
Mount Sinai Hospital, Toronto, Ontario, Canada

Drug Development Updates

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