MedPath

Vitamin C

Generic Name
Vitamin C
Brand Names
Ascor, Citranatal B-calm Kit, Concept Ob, Ferralet 90, Hematogen, Infuvite, Infuvite Pediatric, Moviprep, Mvc-fluoride, Mvi Pediatric, Natafort, Plenvu, Pregvit, Vitafol-one
Drug Type
Small Molecule
Chemical Formula
C6H8O6
CAS Number
50-81-7
Unique Ingredient Identifier
PQ6CK8PD0R
Background

A six carbon compound related to glucose. It is found naturally in citrus fruits and many vegetables. Ascorbic acid is an essential nutrient in human diets, and necessary to maintain connective tissue and bone. Its biologically active form, vitamin C, functions as a reducing agent and coenzyme in several metabolic pathways. Vitamin C is considered an antioxidant.

Indication

Used to treat vitamin C deficiency, scurvy, delayed wound and bone healing, urine acidification, and in general as an antioxidant. It has also been suggested to be an effective antiviral agent.

Associated Conditions
Common Cold, Deficiency, Vitamin A, Deficiency, Vitamin D, Fever, Flu caused by Influenza, Folate deficiency, Iron Deficiency (ID), Iron Deficiency Anemia (IDA), Oral bacterial infection, Scurvy, Vitamin C Deficiency, Vitamin Deficiency
Associated Therapies
Nutritional supplementation, Vitamin supplementation
Clinical Trials
Related News

Vitamin C, Hydrocortisone and Thiamine in Patients With Septic Shock

Phase 3
Terminated
Conditions
Septic Shock
Sepsis
Interventions
Other: Placebo
First Posted Date
2022-01-14
Last Posted Date
2024-01-30
Lead Sponsor
Hospital Sirio-Libanes
Target Recruit Count
71
Registration Number
NCT05192213
Locations
🇧🇷

Hospital Clínica São Roque, Ipiaú, Bahia, Brazil

🇧🇷

Hospital Felício Rocho, Belo Horizonte, Minas Gerais, Brazil

🇧🇷

Hospital Otoclinica, Fortaleza, Ceara, Brazil

and more 9 locations

Real Word Evidence With 1L Polyethylene Glycol (PEG)+ Ascorbic Acid in Iberia

Completed
Conditions
Colon Disease
Colon Cleansing
Colon Cancer
First Posted Date
2022-01-03
Last Posted Date
2022-05-31
Lead Sponsor
Norgine
Target Recruit Count
13393
Registration Number
NCT05174845
Locations
🇪🇸

Hospital San Rafael, A Coruña, Spain

🇪🇸

HM Sant Jordi, Barcelona, Spain

🇪🇸

Consorci Corporació Sanitària Parc Taulí, Sabadell, Barcelona, Spain

and more 9 locations

The Effect of Vitamin C on GCF Total Oxidant Capacity in Smoker Patients With Periodontitis

Early Phase 1
Conditions
Vitamin C Deficiency
Interventions
First Posted Date
2021-08-17
Last Posted Date
2022-03-07
Lead Sponsor
Cairo University
Target Recruit Count
40
Registration Number
NCT05009355
Locations
🇪🇬

Abeer Hassan Sharafuddin, Cairo, Egypt

Evaluation of Safety and Dosing of a Vitamin C Bundle for Sepsis Treatment in Africa

Phase 2
Conditions
Sepsis
Septic Shock
HIV
Interventions
First Posted Date
2021-08-10
Last Posted Date
2021-09-08
Lead Sponsor
Liverpool School of Tropical Medicine
Target Recruit Count
60
Registration Number
NCT04999137
Locations
🇺🇬

Infectious Diseases Institute, Makerere University, Kampala, Uganda

🇺🇬

Kiruddu National Referral Hospital, Kampala, Uganda

Clinical Trial With N-acetylcysteine and Bromhexine for COVID-19

First Posted Date
2021-06-16
Last Posted Date
2021-06-30
Lead Sponsor
Universidade Federal do Ceara
Target Recruit Count
219
Registration Number
NCT04928495
Locations
🇧🇷

Núcleo de Biomedicina - NUBIMED, Fortaleza, Ceará, Brazil

A Safety Study of Pharmacologic Ascorbate and Ferumoxytol in Addition to Standard of Care Chemoradiation in Glioblastoma

Phase 1
Active, not recruiting
Conditions
Glioblastoma
Glioblastoma Multiforme
Interventions
Radiation: External beam radiation therapy
First Posted Date
2021-05-25
Last Posted Date
2024-12-30
Lead Sponsor
Bryan Allen
Target Recruit Count
17
Registration Number
NCT04900792
Locations
🇺🇸

Department of Radiation Oncology at University of Iowa, Iowa City, Iowa, United States

Gemcitabine With Ascorbate Including Adolescents

Early Phase 1
Withdrawn
Conditions
Metastatic Bone Sarcoma
Bone Sarcoma
Unresectable Soft Tissue Sarcoma
Unresectable Bone Sarcoma
Soft Tissue Sarcoma
Metastatic Soft-tissue Sarcoma
Interventions
First Posted Date
2021-05-07
Last Posted Date
2023-02-22
Lead Sponsor
David Dickens
Registration Number
NCT04877587
Locations
🇺🇸

University of Iowa Hospitals & Clinics, Iowa City, Iowa, United States

Reversing Glucose and Lipid-mediated Vascular Dysfunction

Early Phase 1
Recruiting
Conditions
Hypertension
Blood Pressure
Interventions
Drug: Dextrose 20 % in 500 ML Injection
Drug: Saline
First Posted Date
2021-04-05
Last Posted Date
2024-10-08
Lead Sponsor
University of Kansas Medical Center
Target Recruit Count
46
Registration Number
NCT04832009
Locations
🇺🇸

University of Kansas Medical Center, Kansas City, Kansas, United States

Preoperative IMRT With Concurrent High-dose Vitamin C and mFOLFOX6 in Locally Advanced Rectal Cancer

Phase 2
Recruiting
Conditions
Rectal Cancer
Interventions
First Posted Date
2021-03-17
Last Posted Date
2021-03-17
Lead Sponsor
Zhou Fuxiang
Target Recruit Count
60
Registration Number
NCT04801511
Locations
🇨🇳

Zhongnan Hopital of Wuhan University, Wuhan, Hubei, China

The Effects of ATLAS Therapy on Nitric Oxide Bioavailability in Patients With Intermittent Claudication

Phase 1
Recruiting
Conditions
Peripheral Artery Disease
Claudication, Intermittent
Peripheral Vascular Diseases
Interventions
First Posted Date
2021-03-16
Last Posted Date
2025-04-06
Lead Sponsor
Louis Messina
Target Recruit Count
10
Registration Number
NCT04800692
Locations
🇺🇸

UMASS Memorial Healthcare - University Campus, Worcester, Massachusetts, United States

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