Vitamin C
- Generic Name
- Vitamin C
- Brand Names
- Ascor, Citranatal B-calm Kit, Concept Ob, Ferralet 90, Hematogen, Infuvite, Infuvite Pediatric, Moviprep, Mvc-fluoride, Mvi Pediatric, Natafort, Plenvu, Pregvit, Vitafol-one
- Drug Type
- Small Molecule
- Chemical Formula
- C6H8O6
- CAS Number
- 50-81-7
- Unique Ingredient Identifier
- PQ6CK8PD0R
- Background
A six carbon compound related to glucose. It is found naturally in citrus fruits and many vegetables. Ascorbic acid is an essential nutrient in human diets, and necessary to maintain connective tissue and bone. Its biologically active form, vitamin C, functions as a reducing agent and coenzyme in several metabolic pathways. Vitamin C is considered an antioxi...
- Indication
Used to treat vitamin C deficiency, scurvy, delayed wound and bone healing, urine acidification, and in general as an antioxidant. It has also been suggested to be an effective antiviral agent.
- Associated Conditions
- Common Cold, Deficiency, Vitamin A, Deficiency, Vitamin D, Fever, Flu caused by Influenza, Folate deficiency, Iron Deficiency (ID), Iron Deficiency Anemia (IDA), Oral bacterial infection, Scurvy, Vitamin C Deficiency, Vitamin Deficiency
- Associated Therapies
- Nutritional supplementation, Vitamin supplementation
High Dose Vitamin C in Cardiac Surgery Patients
- Conditions
- Interventions
- First Posted Date
- 2016-05-04
- Last Posted Date
- 2019-06-24
- Lead Sponsor
- Virginia Commonwealth University
- Target Recruit Count
- 6
- Registration Number
- NCT02762331
- Locations
- 🇺🇸
Virginia Commonwealth University Health System, Richmond, Virginia, United States
Lead Detoxifying Effects of Ascorbic Acid Among School Going Adolescents of Karachi- A Cluster Randomized Control Trial
- First Posted Date
- 2016-04-20
- Last Posted Date
- 2016-04-26
- Lead Sponsor
- Aga Khan University
- Target Recruit Count
- 144
- Registration Number
- NCT02745873
Randomized, Embedded, Multifactorial Adaptive Platform Trial for Community- Acquired Pneumonia
- Conditions
- Interventions
- Other: No systemic corticosteroidOther: No antiviral agent for COVID-19Other: No immune modulation for COVID-19Drug: Standard course macrolideOther: No antiviral agent for influenzaDrug: Local standard venous thromboprophylaxisOther: No immunoglobulinOther: No simvastatinOther: No cysteamineOther: No Immune Modulator for InfluenzaOther: No vitamin COther: No antiplateletProcedure: Clinician-preferred mechanical ventilation strategyOther: No renin-angiotensin system inhibitorOther: No endothelial modulatorDrug: CeftriaxoneDrug: Moxifloxacin or LevofloxacinDrug: Extended course macrolideDrug: Fixed-duration HydrocortisoneDrug: Five-days oseltamivirDrug: Lopinavir / RitonavirBiological: Convalescent plasmaDrug: Angiotensin converting enzyme inhibitorDrug: Nirmatrelvir/ritonavirDrug: Therapeutic dose anticoagulationProcedure: Protocolised mechanical ventilation strategyDrug: Interferon beta-1aDrug: Vitamin CDrug: SimvastatinDrug: AspirinDrug: EritoranDrug: CysteamineDrug: ImatinibDrug: Shock-dependent hydrocortisoneDrug: Ten-days oseltamivirDrug: P2Y12 inhibitorDrug: Angiotensin Receptor BlockersDrug: Conventional low dose thromboprophylaxisBiological: Delayed administration of convalescent plasmaDrug: Piperacillin-tazobactamDrug: HydroxychloroquineDrug: AnakinraDrug: ApremilastDrug: BaricitinibDrug: RemdesivirDrug: Fixed-duration higher dose HydrocortisoneDrug: Hydroxychloroquine + lopinavir/ritonavirDrug: Intermediate dose thromboprophylaxisDrug: Nirmatrelvir/ritonavir + remdesivirDrug: ARB + DMX-200Drug: CeftarolineDrug: Baloxavir MarboxilDrug: TocilizumabDrug: Amoxicillin-clavulanateDrug: Fixed-duration dexamethasoneDrug: Five-days oseltamivir + baloxavir marboxilDrug: Continuation of therapeutic dose anticoagulationDrug: IvermectinDrug: SarilumabDrug: Ten-days oseltamivir + baloxavir marboxil
- First Posted Date
- 2016-04-13
- Last Posted Date
- 2024-07-12
- Lead Sponsor
- UMC Utrecht
- Target Recruit Count
- 20000
- Registration Number
- NCT02735707
- Locations
- 🇨🇦
Toronto Western Hospital, Toronto, Ontario, Canada
🇺🇸University of Illinois Health, Chicago, Illinois, United States
🇦🇺Bankstown-Lidcombe Hospital, Bankstown, New South Wales, Australia
High Dose Intravenous Ascorbic Acid in Severe Sepsis
- First Posted Date
- 2016-04-12
- Last Posted Date
- 2021-02-16
- Lead Sponsor
- Christiana Care Health Services
- Target Recruit Count
- 24
- Registration Number
- NCT02734147
- Locations
- 🇺🇸
Chrisitana Care Health System-Christiana Hospital, Newark, Delaware, United States
Safety and Efficacy of Vitamin C Infusion in Combination With Local mEHT to Treat Non Small Cell Lung Cancer
- First Posted Date
- 2016-01-14
- Last Posted Date
- 2018-11-30
- Lead Sponsor
- Clifford Hospital, Guangzhou, China
- Target Recruit Count
- 97
- Registration Number
- NCT02655913
- Locations
- 🇨🇳
Clifford Hospital, Guangzhou, China
Preoperative Melatonin or Vitamin C Administration on Postoperative Analgesia
- Conditions
- Interventions
- First Posted Date
- 2015-12-24
- Last Posted Date
- 2021-08-09
- Lead Sponsor
- Cukurova University
- Target Recruit Count
- 55
- Registration Number
- NCT02639741
- Locations
- 🇹🇷
Hakkı Ünlügenç, Adana, Turkey
"Novo C Plus" Vitamin C Containing Dietary Supplement Bioavailability in Healthy Subjects
- First Posted Date
- 2015-11-17
- Last Posted Date
- 2015-11-17
- Lead Sponsor
- Semmelweis University
- Target Recruit Count
- 32
- Registration Number
- NCT02606773
- Locations
- 🇭🇺
Semmelweis University - 1st Departement of Internal Medicine, Budapest, Hungary
Exploratory Study To Assess the Efficacy and Safety of a Triple Combination for Acute Pain Treatment in Patients With Temporomandibular Joint Disorders (TMJD).
- Conditions
- Interventions
- First Posted Date
- 2015-11-11
- Last Posted Date
- 2017-01-19
- Lead Sponsor
- Spherium Biomed
- Target Recruit Count
- 96
- Registration Number
- NCT02602483
- Locations
- 🇪🇸
Hospital Universitario Rey Juan Carlos, Móstoles, Madrid, Spain
🇪🇸Clinica Universitaria Odontològica de la Universitat Internacional de Catalunya, Sant Cugat del Valles, Barcelona, Spain
🇪🇸Hospital Odontològic de la Universitat de Barcelona, Barcelona, Spain
Effect of Vitamin C on Postoperative Pain After Laparoscopic Cholecystectomy
- Conditions
- Interventions
- First Posted Date
- 2015-09-17
- Last Posted Date
- 2016-10-18
- Lead Sponsor
- Taeho Hong
- Target Recruit Count
- 320
- Registration Number
- NCT02553551
- Locations
- 🇰🇷
Department of HBP Surgery, Seoul St. Mary's hospital, Seoul, Seocho-gu, Banopo-dong, Korea, Republic of
Intravenous Ascorbic Acid in Women Receiving Adjuvant or Neo-Adjuvant Chemotherapy for Early Stage Breast Cancer
- First Posted Date
- 2015-08-13
- Last Posted Date
- 2017-06-27
- Lead Sponsor
- Midwestern Regional Medical Center
- Registration Number
- NCT02521077
Drug Development Updates
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