Metformin

Generic Name
Metformin
Brand Names
Actoplus Met, Avandamet, Fortamet, Glucophage, Glucovance, Glumetza, Glycon, Invokamet, Janumet, Jentadueto, Kazano, Kombiglyze, Komboglyze, Qternmet, Riomet, Segluromet, Synjardy, Trijardy, Velmetia, Xigduo
Drug Type
Small Molecule
Chemical Formula
C4H11N5
CAS Number
657-24-9
Unique Ingredient Identifier
9100L32L2N
Background

Metformin is a biguanide antihyperglycemic agent and first-line pharmacotherapy used in the management of type II diabetes.
...

Indication

Metformin immediate-release formulations

Metformin is indicated as an adjunct to diet and exercise to improve glycemic control in adults and pediatric patients ≥10 years old with type 2 diabetes mellitus.

Metformin extended-release tablet (XR)
...

Associated Conditions
Cardiovascular Mortality, End Stage Renal Disease (ESRD), Hospitalizations, Polycystic Ovarian Syndrome (PCOS), Type 2 Diabetes Mellitus, Decreased estimated glomerular filtration rate
Associated Therapies
-

Effect of Metformin in Reducing Fatigue in Long COVID in Adolescents

Phase 3
Not yet recruiting
Conditions
Interventions
First Posted Date
2023-11-27
Last Posted Date
2024-03-04
Lead Sponsor
Purpose Life Sciences
Target Recruit Count
16
Registration Number
NCT06147050
Locations
🇵🇰

Suite No 301, Al-Sehat Centre, Adj Regent Plaza Hotel Rafiqui Shaheed Road, Karachi, Sindh, Pakistan

A Trial to Investigate the Efficacy and Safety of NW Low-Glu® in Patients With Type II Diabetes Mellitus

Phase 3
Not yet recruiting
Conditions
Interventions
First Posted Date
2023-11-20
Last Posted Date
2023-11-22
Lead Sponsor
Natural Wellness Egypt
Target Recruit Count
400
Registration Number
NCT06140485

Effect of Moringa Leaf Capsules on Glycemic Control of Type 2 Diabetic Patients

Phase 2
Conditions
Interventions
First Posted Date
2023-11-09
Last Posted Date
2023-11-09
Lead Sponsor
Islamabad Medical and Dental College
Target Recruit Count
50
Registration Number
NCT06125873
Locations
🇵🇰

Islamabad Medical and Dental College, Islamabad, Federal, Pakistan

Chiglitazar/Metformin in Non-obese Women With PCOS

First Posted Date
2023-11-09
Last Posted Date
2023-11-09
Lead Sponsor
Shengjing Hospital
Target Recruit Count
40
Registration Number
NCT06125587
Locations
🇨🇳

Shengjing Hospital of China Medical University, Shenyang, Liaoning, China

Precision Dosing of Metformin in Youth With T2D

Early Phase 1
Recruiting
Conditions
Interventions
First Posted Date
2023-11-07
Last Posted Date
2024-03-18
Lead Sponsor
University of California, San Francisco
Target Recruit Count
20
Registration Number
NCT06120881
Locations
🇺🇸

UCSF Benioff Children's Hospital San Francisco, Madison Clinic for Pediatric Diabetes, San Francisco, California, United States

🇺🇸

UCSF Benioff Children's Hospital Oakland, Pediatric Diabetes Clinic, Oakland, California, United States

Managing Chronic Tendon Pain by Metformin

First Posted Date
2023-10-25
Last Posted Date
2024-06-07
Lead Sponsor
James Wang
Target Recruit Count
40
Registration Number
NCT06100822
Locations
🇺🇸

University of Pittsburgh, Pittsburgh, Pennsylvania, United States

Preventing Injured Knees From osteoArthritis: Severity Outcomes

First Posted Date
2023-10-23
Last Posted Date
2024-05-09
Lead Sponsor
Brigham and Women's Hospital
Target Recruit Count
512
Registration Number
NCT06096259
Locations
🇺🇸

University of Iowa Hospitals and Clinics, Iowa City, Iowa, United States

🇺🇸

Hospital for Special Surgery, New York, New York, United States

🇺🇸

Emory University, Atlanta, Georgia, United States

and more 6 locations

Effect of Life Style Modification and Metformin on Hypothyroidism With Insulin Resistance

Phase 4
Not yet recruiting
Conditions
Interventions
First Posted Date
2023-10-23
Last Posted Date
2023-10-23
Lead Sponsor
Assiut University
Target Recruit Count
100
Registration Number
NCT06096454

Topical Pentoxifylline; Metformin Versus Betamethasone in the Treatment of Alopecia Areata.

First Posted Date
2023-10-18
Last Posted Date
2023-10-18
Lead Sponsor
Assiut University
Target Recruit Count
60
Registration Number
NCT06087796
Locations
🇪🇬

Assiut university, Assiut, Egypt

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