Metformin
- Generic Name
- Metformin
- Brand Names
- Actoplus Met, Avandamet, Fortamet, Glucophage, Glucovance, Glumetza, Glycon, Invokamet, Janumet, Jentadueto, Kazano, Kombiglyze, Komboglyze, Qternmet, Riomet, Segluromet, Synjardy, Trijardy, Velmetia, Xigduo
- Drug Type
- Small Molecule
- Chemical Formula
- C4H11N5
- CAS Number
- 657-24-9
- Unique Ingredient Identifier
- 9100L32L2N
- Background
Metformin is a biguanide antihyperglycemic agent and first-line pharmacotherapy used in the management of type II diabetes.
...
- Indication
Metformin immediate-release formulations
Metformin is indicated as an adjunct to diet and exercise to improve glycemic control in adults and pediatric patients ≥10 years old with type 2 diabetes mellitus.
Metformin extended-release tablet (XR)
...
- Associated Conditions
- Cardiovascular Mortality, End Stage Renal Disease (ESRD), Hospitalizations, Polycystic Ovarian Syndrome (PCOS), Type 2 Diabetes Mellitus, Decreased estimated glomerular filtration rate
- Associated Therapies
- -
Metformin Treatment in Adolescent Patients With PCOS: A Long-term, Winning Metabolic Choice.
- First Posted Date
- 2023-08-29
- Last Posted Date
- 2023-08-29
- Lead Sponsor
- University of Cagliari
- Target Recruit Count
- 168
- Registration Number
- NCT06015594
Clinical Trials Evaluating the Effect of Metformin Treatment on Function Endometrium in Women Diagnosed With Idiopathic Infertility
- Conditions
- Interventions
- First Posted Date
- 2023-08-25
- Last Posted Date
- 2023-08-25
- Lead Sponsor
- Medical University of Bialystok
- Target Recruit Count
- 200
- Registration Number
- NCT06012682
Effect of Metformin on Carotid Atherosclerosis for Non-diabetic Patients With PsA (CAMPA Study)
- First Posted Date
- 2023-08-14
- Last Posted Date
- 2024-02-07
- Lead Sponsor
- Chinese University of Hong Kong
- Target Recruit Count
- 24
- Registration Number
- NCT05988684
- Locations
- 🇭🇰
The Chinese University of Hong Kong, Hong Kong, Hong Kong
Effect of Laser Puncture Versus Ultraviolet Radiation on Women With Polycystic Ovarian Syndrome
- Conditions
- Interventions
- First Posted Date
- 2023-08-14
- Last Posted Date
- 2024-02-09
- Lead Sponsor
- Cairo University
- Target Recruit Count
- 100
- Registration Number
- NCT05986838
- Locations
- 🇪🇬
Kasr Alainy medical school, Cairo, Egypt
Voxelotor CYP and Transporter Cocktail Interaction Study
- First Posted Date
- 2023-08-08
- Last Posted Date
- 2024-11-22
- Lead Sponsor
- Pfizer
- Target Recruit Count
- 44
- Registration Number
- NCT05981365
- Locations
- 🇺🇸
ICON Early Phase Services, LLC, San Antonio, Texas, United States
Clinical Evaluation of the Effect of Metformin in Sepsis
- First Posted Date
- 2023-08-07
- Last Posted Date
- 2023-09-13
- Lead Sponsor
- German University in Cairo
- Target Recruit Count
- 110
- Registration Number
- NCT05979038
- Locations
- 🇪🇬
Al Demerdash University Hospital, Cairo, Egypt
SGLT2 Inhibitors in Treating Patients with PCOS
- First Posted Date
- 2023-08-01
- Last Posted Date
- 2024-11-07
- Lead Sponsor
- Shanghai 10th People's Hospital
- Target Recruit Count
- 80
- Registration Number
- NCT05966792
- Locations
- 🇨🇳
Shanghai Tenth People'S Hospital, Shanghai, Shanghai, China
Effect of Liraglutide in Obese Women With Polycystic Ovary Syndrome
- First Posted Date
- 2023-07-28
- Last Posted Date
- 2023-08-01
- Lead Sponsor
- Beni-Suef University
- Target Recruit Count
- 120
- Registration Number
- NCT05965908
- Locations
- 🇪🇬
Beni-suef university Hospital, Banī Suwayf, Beni Suef, Egypt
A Trial to Evaluate the Effects of Itraconazole and Carbamazepine on the Pharmacokinetics of Emraclidine and of Emraclidine on the Pharmacokinetics of Metformin in Healthy Adult Participants
- Conditions
- Interventions
- First Posted Date
- 2023-07-28
- Last Posted Date
- 2024-04-02
- Lead Sponsor
- Cerevel Therapeutics, LLC
- Target Recruit Count
- 60
- Registration Number
- NCT05965219
- Locations
- 🇺🇸
Overland Park, Kansas, Overland Park, Kansas, United States
Liraglutide and Metformin Combination on Weight Loss, Metabolic - Endocrine Parameters and Pregnancy Rate in Women With PCOS, Obesity and Infertility
- Conditions
- Interventions
- First Posted Date
- 2023-07-19
- Last Posted Date
- 2023-10-23
- Lead Sponsor
- Mỹ Đức Hospital
- Target Recruit Count
- 188
- Registration Number
- NCT05952882
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.