Minocycline
- Generic Name
- Minocycline
- Brand Names
- Amzeeq, Arestin, Dynacin, Minocin, Minolira, Solodyn, Ximino, Zilxi
- Drug Type
- Small Molecule
- Chemical Formula
- C23H27N3O7
- CAS Number
- 10118-90-8
- Unique Ingredient Identifier
- FYY3R43WGO
- Background
Minocycline was first described in the literacture in 1966. It is a second generation tetracycline antibiotic that is active against gram-negative and gram-positive bacteria. Like other semisynthetic tetracyclines, minocycline has modifications to carbons 7-9 on the D ring to generate higher efficacy than previous tetracyclines.
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- Indication
Oral and topical minocycline are indicated to treat inflammatory lesions of acne vulgaris. Subgingival microspheres are indicated as an adjunct treatment in the reduction of pocket depth in adults with periodontitis. Oral and intravenous formulations are indicated to treat infections of susceptible microorganisms. These include rickettsiae, Mycoplasma pneumo...
- Associated Conditions
- Bartonellosis, Brucellosis, Campylobacter fetus, Chancroid, Cholera (Disorder), Conjunctivitis, Inclusion, Granuloma Inguinale, Lymphogranuloma Venereum, Nongonococcal urethritis, Periodontitis, Plague, Psittacosis, Q Fever, Relapsing Fever, Respiratory Tract Infections (RTI), Rickettsia Infections, Rickettsialpox, Rocky Mountain Spotted Fever, Trachoma, Tularemia, Typhus infections, Inflammatory lesions
- Associated Therapies
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Stony Brook Medicine Anti-Inflammatory Trial
- Conditions
- Interventions
- First Posted Date
- 2024-11-21
- Last Posted Date
- 2024-11-21
- Lead Sponsor
- Stony Brook University
- Target Recruit Count
- 42
- Registration Number
- NCT06699966
Study on the Efficacy and Safety of Berberine, Minocycline, Esomeprazole, and Colloidal Bismuth Quadruple Therapy in the Initial Treatment of Helicobacter Pylori.
- Conditions
- Interventions
- First Posted Date
- 2024-09-19
- Last Posted Date
- 2024-09-19
- Lead Sponsor
- Xijing Hospital of Digestive Diseases
- Target Recruit Count
- 548
- Registration Number
- NCT06603688
- Locations
- 🇨🇳
Xijing Hosipital of Digestive Disease, Xian, Shaanxi, China
Efficacy and Safety of Tegoprazan and Minocycline Dual Therapy for Helicobacter Pylori Initial Treatment
- Conditions
- Interventions
- First Posted Date
- 2024-07-26
- Last Posted Date
- 2024-07-30
- Lead Sponsor
- Xijing Hospital of Digestive Diseases
- Target Recruit Count
- 208
- Registration Number
- NCT06523764
Efficacy and Safety of Tranilast Combined With Minocycline in the Treatment of Rosacea
- First Posted Date
- 2024-03-12
- Last Posted Date
- 2024-03-12
- Target Recruit Count
- 45
- Registration Number
- NCT06307288
- Locations
- 🇨🇳
The Second Affiliated Hospital of Xi'an Jiaotong Universi, Xi'an, Shaanxi, China
Effect of Minocycline on Inflammation in Depressed Patients
- First Posted Date
- 2024-01-17
- Last Posted Date
- 2024-01-17
- Target Recruit Count
- 60
- Registration Number
- NCT06207760
- Locations
- 🇮🇹
IRCCS Centro San Giovanni di Dio Fatebenefratelli, Brescia, Italy
Minocyclin in Ulcerative Colitis as Added on Therapy
- Conditions
- Interventions
- First Posted Date
- 2024-01-11
- Last Posted Date
- 2024-01-30
- Lead Sponsor
- Mostafa Bahaa
- Target Recruit Count
- 46
- Registration Number
- NCT06201793
- Locations
- 🇪🇬
Faculty of Medicine, Mansoura University, Mansoura, Egypt
Enhanced Dermatological Care to Reduce Rash and Paronychia in Epidermal Growth Factor Receptor (EGRF)-Mutated Non-Small Cell Lung Cancer (NSCLC) Treated First-line With Amivantamab Plus Lazertinib
- First Posted Date
- 2023-11-07
- Last Posted Date
- 2024-12-05
- Lead Sponsor
- Janssen Research & Development, LLC
- Target Recruit Count
- 200
- Registration Number
- NCT06120140
- Locations
- 🇺🇸
USC Norris Oncology Hematology Newport Beach, Newport Beach, California, United States
🇺🇸Kaiser Permanente Oakland Medical Center, Oakland, California, United States
🇺🇸Kaiser Permanente Roseville Medical Center, Roseville, California, United States
Maimonides Minocycline in Stroke Study
- Conditions
- Interventions
- First Posted Date
- 2023-10-30
- Last Posted Date
- 2023-11-18
- Lead Sponsor
- Maimonides Medical Center
- Target Recruit Count
- 1120
- Registration Number
- NCT06107725
- Locations
- 🇺🇸
Maimonides Medical Center, Brooklyn, New York, United States
Brain and Stress Study
- Conditions
- Interventions
- First Posted Date
- 2023-09-21
- Last Posted Date
- 2024-12-18
- Lead Sponsor
- University of North Carolina, Chapel Hill
- Target Recruit Count
- 10
- Registration Number
- NCT06044090
- Locations
- 🇺🇸
Howell Hall, Chapel Hill, North Carolina, United States
Efficacy and Safety of Adjunctive Minocycline in the Treatment of Autoimmune Encephalitis
- First Posted Date
- 2023-09-13
- Last Posted Date
- 2023-09-13
- Lead Sponsor
- Xijing Hospital
- Target Recruit Count
- 40
- Registration Number
- NCT06033846
- Locations
- 🇨🇳
Xijing Hospital, Xi'an, China
Drug Development Updates
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