Antithymocyte immunoglobulin (rabbit)

Generic Name
Antithymocyte immunoglobulin (rabbit)
Brand Names
-
Drug Type
Biotech
Chemical Formula
-
CAS Number
308067-60-9
Unique Ingredient Identifier
D7RD81HE4W
Background

Rabbit anti-thymocyte globulin. Thymoglobulin is a polyclonal antibody that suppresses certain types of immune cells responsible for acute organ rejection in transplant patients. Thymoglobulin is a mixture of antibodies intended to bind to various cell surface antigens. The most common mode of action of Thymoglobulin is via selective depletion of T-cells.

Indication

For prevention of renal transplant rejection

Associated Conditions
Rejection Acute Renal
Associated Therapies
-

The Effect and Safety Profile of Thymoglobulin® in Primary Cardiac Transplant Recipients

First Posted Date
2017-09-26
Last Posted Date
2024-12-16
Lead Sponsor
Cedars-Sinai Medical Center
Target Recruit Count
60
Registration Number
NCT03292861
Locations
🇺🇸

Cedars-Sinai Medical Center, Los Angeles, California, United States

🇺🇸

Kaiser Permanente Los Angeles Medical Center, Los Angeles, California, United States

Autologous Stem Cell Transplant for Crohn's Disease

First Posted Date
2017-07-17
Last Posted Date
2024-09-30
Lead Sponsor
Aaron Etra
Target Recruit Count
50
Registration Number
NCT03219359
Locations
🇺🇸

Icahn School of Medicine at Mount Sinai, New York, New York, United States

A Optimal Anti-Thymoglobuline (ATG) Dose Decrease cGVHD But Not Increase Leukemia Relapse for Haplo-HSCT

First Posted Date
2017-06-19
Last Posted Date
2017-06-19
Lead Sponsor
Zhujiang Hospital
Target Recruit Count
192
Registration Number
NCT03190733

Haploidentical Hematopoietic Stem Cell Transplantation for Patients With Thalassemia Major

First Posted Date
2017-05-31
Last Posted Date
2017-05-31
Lead Sponsor
First Affiliated Hospital of Guangxi Medical University
Target Recruit Count
30
Registration Number
NCT03171831
Locations
🇨🇳

First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China

Kinetic Study of CD8+ CMV-specific Cellular Immunity in Renal Transplant Patients After Receiving Thymoglobulin

Completed
Conditions
Interventions
First Posted Date
2017-05-10
Last Posted Date
2021-07-20
Lead Sponsor
Maimónides Biomedical Research Institute of Córdoba
Target Recruit Count
150
Registration Number
NCT03147183
Locations
🇪🇸

Hosìtal Universitario Reina Sofia, Córdoba, Spain

Study of HLA-Haploidentical Stem Cell Transplantation to Treat Clinically Aggressive Sickle Cell Disease

First Posted Date
2017-04-19
Last Posted Date
2024-11-12
Lead Sponsor
University of Illinois at Chicago
Target Recruit Count
50
Registration Number
NCT03121001
Locations
🇺🇸

University of Illinois at Chicago, Chicago, Illinois, United States

Efficacy and Safety of Rabbit Antithymocyte Globulin 3mg/kg in Kidney Transplant Patients Under Steroid-free and CNI Minimization Maintenance Immunosuppressive Regimen

Phase 4
Conditions
Interventions
First Posted Date
2017-03-23
Last Posted Date
2019-02-22
Lead Sponsor
Hospital Geral de Fortaleza
Target Recruit Count
200
Registration Number
NCT03088280
Locations
🇧🇷

Transplant ward of the Hospital do Fortaleza, Fortaleza, Ceará, Brazil

Basiliximab vs Low-dose Thymoglobulin Induction Therapy in Low Risk Kidney Transplant Patients

First Posted Date
2016-12-30
Last Posted Date
2019-11-15
Lead Sponsor
Coordinación de Investigación en Salud, Mexico
Target Recruit Count
100
Registration Number
NCT03006419
Locations
🇲🇽

Umae Hospital Especialidades 14 Adolfo Ruiz Cortines, Veracruz, Mexico

Abatacept for GVHD Prophylaxis After Hematopoietic Stem Cell Transplantation for Pediatric Sickle Cell Disease

First Posted Date
2016-08-16
Last Posted Date
2024-06-13
Lead Sponsor
Monica Bhatia
Target Recruit Count
24
Registration Number
NCT02867800
Locations
🇺🇸

North Carolina Cancer Hospital, Chapel Hill, North Carolina, United States

🇺🇸

Columbia University Irving Medical Center, New York, New York, United States

🇺🇸

Children's National Medical Center, Washington, District of Columbia, United States

and more 4 locations
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