Pamidronic acid
- Generic Name
- Pamidronic acid
- Brand Names
- Pamisol
- Drug Type
- Small Molecule
- Chemical Formula
- C3H11NO7P2
- CAS Number
- 40391-99-9
- Unique Ingredient Identifier
- OYY3447OMC
Overview
Pamidronic acid is a second generation, nitrogen containing bisphosphonate similar to neridronic acid and alendronic acid. Pamidronic acid was first described in the literature in 1977. The second generation bisphosphonates are less common as third generation bisphosphonates, such as ibandronic acid, zoledronic acid, minodronic acid, and risedronic acid are becoming more popular. Pamidronic acid was granted FDA approval on 31 October 1991.
Background
Pamidronic acid is a second generation, nitrogen containing bisphosphonate similar to neridronic acid and alendronic acid. Pamidronic acid was first described in the literature in 1977. The second generation bisphosphonates are less common as third generation bisphosphonates, such as ibandronic acid, zoledronic acid, minodronic acid, and risedronic acid are becoming more popular. Pamidronic acid was granted FDA approval on 31 October 1991.
Indication
Pamidronate is indicated to treat moderate to severe hypercalcemia of malignancy, moderate to severe Paget's disease of bone, osteolytic bone metastases of breast cancer, and osteolytic lesions of multiple myeloma.
Associated Conditions
- Hypercalcemia of Malignancy
- Osteolytic lesion
- Paget’s Disease
- Osteolytic Bone metastases
Clinical Trials
FDA Approved Products
Singapore Approved Products
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