Clindamycin
- Generic Name
- Clindamycin
- Brand Names
- Acanya, Benzaclin, Biacna, Cabtreo, Cleocin, Cleocin-T, Clindacin, Clindagel, Clindesse, Clindoxyl, Dalacin, Dalacin C, Duac, Evoclin, Neuac, Onexton, Veltin, Xaciato, Ziana
- Drug Type
- Small Molecule
- Chemical Formula
- C18H33ClN2O5S
- CAS Number
- 18323-44-9
- Unique Ingredient Identifier
- 3U02EL437C
- Background
Clindamycin is a semi-synthetic lincosamide antibiotic used in the treatment of a variety of serious infections due to susceptible microorganisms as well as topically for acne vulgaris. It has a relatively narrow spectrum of activity that includes anaerobic bacteria as well as gram-positive cocci and bacilli and gram-negative bacilli. Interestingly, clindamy...
- Indication
In oral and parenteral formulations, clindamycin is indicated for the treatment of serious infections caused by susceptible anaerobic bacteria, as well as susceptible staphylococci, streptococci, and pneumococci. Used topically, it is indicated for the treatment of acne vulgaris and is available in combination with benzoyl peroxide or tretinoin for this purp...
- Associated Conditions
- Abscess, Intra-Abdominal caused by Anaerobic Bacterial Infection, Acne Vulgaris, Babesiosis, Bacterial Endocarditis, Bacterial Vaginosis (BV), Bloodstream Infections caused by Anaerobic Bacterial Infection, Bone and Joint Infections caused by susceptible Staphylococcus, Empyema caused by Anaerobic Bacterial Infection, Endometritis caused by Anaerobic Bacterial Infection, Lung Abscess caused by Anaerobic Bacterial Infection, Malaria caused by Plasmodium falciparum, Mixed Vaginal Infections, Pelvic cellulitis caused by Anaerobic Bacterial Infection, Peritonitis caused by Anaerobic Bacterial Infection, Pneumocystis Jirovecii Pneumonia, Pneumonitis caused by Anaerobic Bacterial Infection, Respiratory Tract Infections (RTI) caused by susceptible Staphylococcus, Respiratory Tract Infections (RTI) caused by susceptible pneumococci, Respiratory Tract Infections (RTI) caused by susceptible streptococci, Septicemia caused by susceptible Staphylococcus, Septicemia caused by susceptible streptococci, Skin Structures and Soft Tissue Infections caused by Anaerobic Bacterial Infection, Skin Structures and Soft Tissue Infections caused by susceptible Staphylococcus, Skin Structures and Soft Tissue Infections caused by susceptible streptococci, Toxoplasmosis, Tubo-ovarian abscess caused by Anaerobic Bacterial Infection, Vaginal Candidiasis, Vaginal Mycosis, Chronic Bone and Joint Infections caused by Susceptible infections, Moderate Acne vulgaris, Post-surgical vaginal cuff infection caused by Anaerobic Bacterial Infection, Viridans group streptococci
- Associated Therapies
- -
Clostridioides Difficile Controlled Human Infection Model
- Conditions
- Interventions
- First Posted Date
- 2024-11-22
- Last Posted Date
- 2024-11-22
- Lead Sponsor
- Leiden University Medical Center
- Target Recruit Count
- 60
- Registration Number
- NCT06702345
- Locations
- 🇳🇱
Leiden University Medical Center, Leiden, Zuid Holland, Netherlands
Short Versus Standard of Care Antibiotic Duration for Children Hospitalized for CAP
- First Posted Date
- 2024-07-10
- Last Posted Date
- 2024-11-20
- Lead Sponsor
- Medical College of Wisconsin
- Target Recruit Count
- 236
- Registration Number
- NCT06494072
- Locations
- 🇺🇸
Childrens Wisconsin, Milwaukee, Wisconsin, United States
An Oral Doxycycline Regimen to Prevent Bacteremia Following Dental Procedures
- Conditions
- Interventions
- First Posted Date
- 2024-05-20
- Last Posted Date
- 2024-06-17
- Lead Sponsor
- University of Santiago de Compostela
- Target Recruit Count
- 150
- Registration Number
- NCT06422221
- Locations
- 🇪🇸
Santiago de Compostela University Hospital, Santiago De Compostela, A Coruña, Spain
Rifampicin Combination Therapy Versus Monotherapy for Staphylococcal Prosthetic Joint Infection
- Conditions
- Interventions
- First Posted Date
- 2023-12-15
- Last Posted Date
- 2023-12-15
- Lead Sponsor
- Leiden University Medical Center
- Target Recruit Count
- 316
- Registration Number
- NCT06172010
- Locations
- 🇳🇱
Alrijne Ziekenhuis, Leiderdorp, Netherlands
🇳🇱Amsterdam UMC, Amsterdam, Netherlands
🇳🇱Martini ziekenhuis, Groningen, Netherlands
Adjunctive Clindamycin Versus Linezolid for β-lactam Treated Patients With Invasive Group A Streptococcal Infections
- First Posted Date
- 2023-11-13
- Last Posted Date
- 2023-11-13
- Target Recruit Count
- 1000
- Registration Number
- NCT06126263
- Locations
- 🇺🇸
National Institutes of Health Clinical Center (primary center conducting large database study), Bethesda, Maryland, United States
Enhanced Dermatological Care to Reduce Rash and Paronychia in Epidermal Growth Factor Receptor (EGRF)-Mutated Non-Small Cell Lung Cancer (NSCLC) Treated First-line With Amivantamab Plus Lazertinib
- First Posted Date
- 2023-11-07
- Last Posted Date
- 2024-12-05
- Lead Sponsor
- Janssen Research & Development, LLC
- Target Recruit Count
- 200
- Registration Number
- NCT06120140
- Locations
- 🇺🇸
USC Norris Oncology Hematology Newport Beach, Newport Beach, California, United States
🇺🇸Kaiser Permanente Oakland Medical Center, Oakland, California, United States
🇺🇸Kaiser Permanente Roseville Medical Center, Roseville, California, United States
Adjunctive Clindamycin for the Treatment of Skin and Soft Tissue Infections, a Randomized Controlled Trial
- Conditions
- Interventions
- First Posted Date
- 2023-06-12
- Last Posted Date
- 2024-12-09
- Lead Sponsor
- Frieder Schaumburg
- Target Recruit Count
- 100
- Registration Number
- NCT05899140
- Locations
- 🇸🇱
Masanga Hospital, Masanga, Sierra Leone
CAT BITE Antibiotic Prophylaxis for the Hand/Forearm (CATBITE)
- First Posted Date
- 2023-05-06
- Last Posted Date
- 2024-10-01
- Lead Sponsor
- University of Missouri-Columbia
- Target Recruit Count
- 72
- Registration Number
- NCT05846399
- Locations
- 🇺🇸
University of Missouri, Columbia, Missouri, United States
Different Oral Doses of Clindamycin in Preventing Post-operative Sequelae of Lower Third Molar Surgery
- First Posted Date
- 2022-03-07
- Last Posted Date
- 2022-03-07
- Lead Sponsor
- Oral and Maxillofacial Surgery Clinic, Poland
- Target Recruit Count
- 300
- Registration Number
- NCT05268835
- Locations
- 🇵🇱
OMFS Clinic, Zgierz, Poland
The Effect of Clindamycin and a Live Biotherapeutic on the Reproductive Outcomes of IVF Patients With Abnormal Vaginal Microbiota
- Conditions
- Interventions
- First Posted Date
- 2021-12-22
- Last Posted Date
- 2023-07-06
- Lead Sponsor
- Peter Humaidan
- Target Recruit Count
- 333
- Registration Number
- NCT05166746
- Locations
- 🇩🇰
Stork Fertility Clinic VivaNeo, Copenhagen, Denmark
🇩🇰Hvidovre Hospital, The Fertility Clinic, Hvidovre, Denmark
🇩🇰Fertility Clinic Skive, Skive Regional Hospital, Skive, Denmark
Drug Development Updates
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