Sertraline

Generic Name
Sertraline
Brand Names
Zoloft
Drug Type
Small Molecule
Chemical Formula
C17H17Cl2N
CAS Number
79617-96-2
Unique Ingredient Identifier
QUC7NX6WMB
Background

Sertraline is a popular antidepressant medication commonly known as a selective serotonin reuptake inhibitor (SSRI), and is similar to drugs such as Citalopram and Fluoxetine. Despite marked structural differences between compounds in this drug class, SSRIs exert similar pharmacological effects.
...

Indication

Sertraline is indicated for the management of major depressive disorder (MDD), post-traumatic stress disorder (PTSD), obsessive-compulsive disorder (OCD), panic disorder (PD), premenstrual dysphoric disorder (PMDD), and social anxiety disorder (SAD). Common off-label uses for sertraline include the prevention of post stroke depression, generalized anxiety di...

Associated Conditions
Binge Eating Disorder (BED), Bulimia Nervosa, Generalized Anxiety Disorder, Major Depressive Disorder (MDD), Obsessive Compulsive Disorder (OCD), Panic Disorder, Post Traumatic Stress Disorder (PTSD), Premenstrual Dysphoric Disorder (PMDD), Social Anxiety Disorder (SAD)
Associated Therapies
-

Treatments for Depression: Drug Versus Psychotherapy

First Posted Date
2002-08-12
Last Posted Date
2017-06-02
Lead Sponsor
University of Pennsylvania
Target Recruit Count
156
Registration Number
NCT00043550
Locations
🇺🇸

University of Pennsylvania, Philadelphia, Pennsylvania, United States

Depression and Health Outcomes in Refractory Epilepsy

First Posted Date
2001-11-15
Last Posted Date
2017-11-06
Lead Sponsor
Columbia University
Target Recruit Count
140
Registration Number
NCT00026637
Locations
🇺🇸

Washington University School of Medicine, Saint Louis, Missouri, United States

🇺🇸

Columbia University Medical Center, New York, New York, United States

Sequenced Treatment Alternatives to Relieve Depression (STAR*D)

Phase 4
Completed
Conditions
First Posted Date
2001-07-23
Last Posted Date
2009-09-25
Lead Sponsor
National Institute of Mental Health (NIMH)
Target Recruit Count
4000
Registration Number
NCT00021528
Locations
🇺🇸

Harbor UCLA Family Health Care Center, Harbor City, California, United States

🇺🇸

UCLA General Outpatient Psychiatry Clinic, Los Angeles, California, United States

🇺🇸

UCLA Internal Medicine Clinic, Los Angeles, California, United States

and more 38 locations

Tiagabine, Sertraline, or Donepezil for the Treatment of Cocaine Dependence - 9

Phase 2
Completed
Conditions
First Posted Date
2001-04-18
Last Posted Date
2017-01-12
Lead Sponsor
National Institute on Drug Abuse (NIDA)
Registration Number
NCT00015132
Locations
🇺🇸

Cincinnati MDRU, Cincinnati, Ohio, United States

Treatment of Major Depression With St. John's Wort (Hypericum)

Not Applicable
Completed
Conditions
First Posted Date
2000-04-03
Last Posted Date
2014-04-08
Lead Sponsor
National Institute of Mental Health (NIMH)
Registration Number
NCT00005013
Locations
🇺🇸

Univ of Cincinnati Medical Ctr, Cincinnati, Ohio, United States

🇺🇸

Univ of Texas Southwestern Med Ctr, Dallas, Texas, United States

🇺🇸

Seattle Clinical Research Center, Seattle, Washington, United States

and more 9 locations

Treatment of Obsessive-Compulsive Disorder (OCD) in Children

Phase 3
Completed
Conditions
First Posted Date
1999-11-03
Last Posted Date
2016-08-22
Lead Sponsor
University of Pennsylvania
Registration Number
NCT00000384
Locations
🇺🇸

Duke Univ. Med. Ctr., Durham, North Carolina, United States

🇺🇸

Univ of Pennsylvania, Philadelphia, Pennsylvania, United States

Drug Therapy for Alcohol Dependence in Alaska Natives (Naltrexone/Sertraline)

First Posted Date
1999-11-03
Last Posted Date
2013-01-29
Lead Sponsor
Yale University
Target Recruit Count
198
Registration Number
NCT00000451

Antidepressant Treatment of Melancholia in Late Life

Phase 4
Completed
Conditions
Interventions
First Posted Date
1999-11-03
Last Posted Date
2015-10-07
Lead Sponsor
New York State Psychiatric Institute
Target Recruit Count
110
Registration Number
NCT00000378
Locations
🇺🇸

1051 Riverside Drive, New York, New York, United States

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