Sertraline
- Generic Name
- Sertraline
- Brand Names
- Zoloft
- Drug Type
- Small Molecule
- Chemical Formula
- C17H17Cl2N
- CAS Number
- 79617-96-2
- Unique Ingredient Identifier
- QUC7NX6WMB
- Background
Sertraline is a popular antidepressant medication commonly known as a selective serotonin reuptake inhibitor (SSRI), and is similar to drugs such as Citalopram and Fluoxetine. Despite marked structural differences between compounds in this drug class, SSRIs exert similar pharmacological effects.
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- Indication
Sertraline is indicated for the management of major depressive disorder (MDD), post-traumatic stress disorder (PTSD), obsessive-compulsive disorder (OCD), panic disorder (PD), premenstrual dysphoric disorder (PMDD), and social anxiety disorder (SAD). Common off-label uses for sertraline include the prevention of post stroke depression, generalized anxiety di...
- Associated Conditions
- Binge Eating Disorder (BED), Bulimia Nervosa, Generalized Anxiety Disorder, Major Depressive Disorder (MDD), Obsessive Compulsive Disorder (OCD), Panic Disorder, Post Traumatic Stress Disorder (PTSD), Premenstrual Dysphoric Disorder (PMDD), Social Anxiety Disorder (SAD)
- Associated Therapies
- -
Sertraline in Generalized Social Phobia With Co-Occurring Anxiety and Mood Disorders
- Conditions
- Interventions
- First Posted Date
- 2005-09-16
- Last Posted Date
- 2018-03-22
- Lead Sponsor
- Hamilton Health Sciences Corporation
- Target Recruit Count
- 170
- Registration Number
- NCT00182533
- Locations
- 🇨🇦
MacAnxiety Research Centre, Hamilton, Ontario, Canada
A Study of Sertraline to Prevent PTSD
- Conditions
- Interventions
- First Posted Date
- 2005-09-16
- Last Posted Date
- 2014-08-05
- Lead Sponsor
- Massachusetts General Hospital
- Target Recruit Count
- 26
- Registration Number
- NCT00182078
- Locations
- 🇺🇸
Massachusetts General Hospital, Boston, Massachusetts, United States
Sertraline for Preventing Post-stroke Depression and Improving Rehabilitation Outcomes
- Conditions
- Interventions
- First Posted Date
- 2005-09-15
- Last Posted Date
- 2014-06-27
- Lead Sponsor
- University of Pittsburgh
- Target Recruit Count
- 154
- Registration Number
- NCT00177424
- Locations
- 🇺🇸
University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, United States
Dynamic Measures of Neurochemistry in Mood Disorders
- Conditions
- First Posted Date
- 2005-09-15
- Last Posted Date
- 2017-04-11
- Lead Sponsor
- Vanderbilt University Medical Center
- Target Recruit Count
- 42
- Registration Number
- NCT00178828
- Locations
- 🇺🇸
Vanderbilt University Medical Center, Nashville, Tennessee, United States
Sertraline vs. Venlafaxine XR
- Conditions
- First Posted Date
- 2005-09-15
- Last Posted Date
- 2015-06-02
- Lead Sponsor
- Vanderbilt University
- Target Recruit Count
- 20
- Registration Number
- NCT00179283
- Locations
- 🇺🇸
Vanderbilt University Medical Center, Nashville, Tennessee, United States
Triiodothyronine (T3) Supplementation in the Treatment of Bipolar and Unipolar Depression.
- Conditions
- First Posted Date
- 2005-09-12
- Last Posted Date
- 2007-01-04
- Lead Sponsor
- Hadassah Medical Organization
- Target Recruit Count
- 220
- Registration Number
- NCT00158990
- Locations
- 🇺🇸
Global Medical Institutes, Princeton, New Jersey, United States
🇮🇱Hadassah Medical Organisation, Jerusalem, Israel
Treatments for Psychogenic Nonepileptic Seizures (NES)
- Conditions
- Interventions
- First Posted Date
- 2005-09-12
- Last Posted Date
- 2014-11-20
- Lead Sponsor
- Rhode Island Hospital
- Target Recruit Count
- 38
- Registration Number
- NCT00159965
- Locations
- 🇺🇸
Rhode Island Hospital, Providence, Rhode Island, United States
Multicentre Trial to Evaluate the Safety and Efficacy of CP-316,311 in Major Depressive Disorder
- Conditions
- First Posted Date
- 2005-09-02
- Last Posted Date
- 2008-03-24
- Lead Sponsor
- Pfizer
- Target Recruit Count
- 200
- Registration Number
- NCT00143091
- Locations
- 🇷🇺
Pfizer Investigational Site, St.-Petersburg, Russian Federation
Comparison of Two Treatments for Post-Traumatic Stress Disorder
- Conditions
- Interventions
- First Posted Date
- 2005-08-08
- Last Posted Date
- 2022-05-24
- Lead Sponsor
- Case Western Reserve University
- Target Recruit Count
- 200
- Registration Number
- NCT00127673
- Locations
- 🇺🇸
Department of Psychology, University of Washington, Seattle, Washington, United States
Therapies for Treatment-Resistant Panic Disorder Symptoms
- Conditions
- Interventions
- First Posted Date
- 2005-07-11
- Last Posted Date
- 2014-06-11
- Lead Sponsor
- Massachusetts General Hospital
- Target Recruit Count
- 46
- Registration Number
- NCT00118417
- Locations
- 🇺🇸
Massachusetts General Hospital, Boston, Massachusetts, United States
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.