Sugammadex

Generic Name
Sugammadex
Brand Names
Bridion, Sugammadex Adroiq, Sugammadex Amomed, Sugammadex Fresenius Kabi, Sugammadex Mylan, Sugammadex Piramal
Drug Type
Small Molecule
Chemical Formula
C72H112O48S8
CAS Number
343306-71-8
Unique Ingredient Identifier
361LPM2T56
Background

Sugammadex is a selective relaxant binding agent indicated for reversal of neuromuscular blockade induced by rocuronium bromide and vecuronium bromide during surgery. Rocuronium bromide and vecuronium bromide are neuromuscular blocking medications that cause temporary paralysis and are especially useful for general anesthesia, ventilation, or tracheal intuba...

Indication

Sugammadex is indicated for the reversal of neuromuscular blockade induced by rocuronium bromide or vecuronium bromide in adults and pediatric patients ≥2 years old who are undergoing surgery.

Associated Conditions
Neuromuscular blockade caused by vecuronium bromide
Associated Therapies
-

Sugammadex on Laparoscopic Bariatric Surgery

Not Applicable
Not yet recruiting
Conditions
Interventions
First Posted Date
2024-11-07
Last Posted Date
2024-11-07
Lead Sponsor
Shanxi Bethune Hospital
Target Recruit Count
60
Registration Number
NCT06678451

Placental Transfer of Sugammadex in the Human Placental Perfusion Model

Not Applicable
Not yet recruiting
Conditions
Interventions
First Posted Date
2024-10-09
Last Posted Date
2024-10-09
Lead Sponsor
Universitaire Ziekenhuizen KU Leuven
Target Recruit Count
16
Registration Number
NCT06634355
Locations
🇧🇪

UZ Leuven, Leuven, Vlaams-Brabant, Belgium

Sugammadex and Time to Extubation in Ophthalmic Surgery

First Posted Date
2024-10-08
Last Posted Date
2024-10-08
Lead Sponsor
China Medical University Hospital
Target Recruit Count
262
Registration Number
NCT06632067
Locations
🇨🇳

China Medical University Hospital, Taichung, Taiwan

Sugammadex Dose Finding Under Two Years Old

Phase 2
Not yet recruiting
Conditions
Interventions
First Posted Date
2024-08-28
Last Posted Date
2024-08-29
Lead Sponsor
Sang-Hwan Ji
Target Recruit Count
33
Registration Number
NCT06575036
Locations
🇰🇷

Seoul National University Hospital, Seoul, Korea, Republic of

Efficacy and Safety of Sugammadex in Thoracoscopy Thymectomy for Chinese Adults With Myasthenia Gravis

Not Applicable
Recruiting
Conditions
Interventions
First Posted Date
2024-05-31
Last Posted Date
2024-06-27
Lead Sponsor
Beijing Tongren Hospital
Target Recruit Count
64
Registration Number
NCT06436768
Locations
🇨🇳

Beijing tongren Hospital, Capital Medical University, Beijing, Beijing, China

🇨🇳

The First Affiliated Hospital with Nanjing Medical University, Nanjing, Jiangsu, China

Neostigmine/Glyco-pyrrolate 50 Mikrogram/kg or Sugammadex 2 mg/kg for Reversal of Neuromuscular Blockade in Elderly Patients

First Posted Date
2024-01-29
Last Posted Date
2024-01-29
Lead Sponsor
Matias Vested
Target Recruit Count
40
Registration Number
NCT06228092
Locations
🇩🇰

Department of anaesthesia, Centre of Head and Orthopedics, Rigshospitalet, Copenhagen, Denmark

🇩🇰

Bispebjerg Hospital, Copenhagen, Denmark

🇩🇰

Department of Pediatric and Obstetric Anaesthesia, Rigshospitalet, Copenhagen, Denmark

Muscle Relaxation for Pediatric Adenotonsillectomy

First Posted Date
2024-01-26
Last Posted Date
2024-12-04
Lead Sponsor
University of Texas Southwestern Medical Center
Target Recruit Count
172
Registration Number
NCT06225466
Locations
🇺🇸

Children's Health Dallas, Dallas, Texas, United States

Effects of Sugammadex and Conventional Reversal on Lung Function in Laparoscopic Abdominal Surgery

First Posted Date
2024-01-18
Last Posted Date
2024-01-18
Lead Sponsor
Rhendra Hardy Mohamad Zaini
Target Recruit Count
80
Registration Number
NCT06210165
Locations
🇲🇾

University of Science Malaysia Hospital, Kubang Kerian, Kelantan, Malaysia

Neostigmine Versus Sugammadex on Renal Functions

Phase 4
Active, not recruiting
Conditions
Interventions
First Posted Date
2023-10-13
Last Posted Date
2023-10-13
Lead Sponsor
Menoufia University
Target Recruit Count
64
Registration Number
NCT06081738
Locations
🇪🇬

Menoufia University Hospitals, Shibīn Al Kawm, Menoufia, Egypt

Pharmacological Reversal of Neuromuscular Blockade in Critically Ill Patients

First Posted Date
2023-08-15
Last Posted Date
2024-06-24
Lead Sponsor
Seoul National University Hospital
Target Recruit Count
30
Registration Number
NCT05993390
Locations
🇰🇷

Seoul National University Hospital, Seoul, Jongno-gu, Korea, Republic of

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