Vortioxetine
- Generic Name
- Vortioxetine
- Brand Names
- Brintellix, Trintellix
- Drug Type
- Small Molecule
- Chemical Formula
- C18H22N2S
- CAS Number
- 508233-74-7
- Unique Ingredient Identifier
- 3O2K1S3WQV
- Background
Vortioxetine is an antidepressant medication indicated for the treatment of major depressive disorder (MDD). It is classified as a serotonin modulator and stimulator (SMS) as it has a multimodal mechanism of action towards the serotonin neurotransmitter system whereby it simultaneously modulates one or more serotonin receptors and inhibits the reuptake of se...
- Indication
用于治疗重度抑郁症成人患者。
- Associated Conditions
- Major Depressive Disorder (MDD)
- Associated Therapies
- -
Vortioxetine for the Treatment of Mood and Cognitive Symptoms in Frontotemporal Dementia
- First Posted Date
- 2024-09-19
- Last Posted Date
- 2024-11-08
- Lead Sponsor
- Johns Hopkins University
- Target Recruit Count
- 50
- Registration Number
- NCT06604520
- Locations
- 🇺🇸
The Johns Hopkins Hospital, Baltimore, Maryland, United States
Using 18F-FPEB PET to Identify mGLUR5 Availability in Affective Disorders
- Conditions
- Interventions
- First Posted Date
- 2023-05-03
- Last Posted Date
- 2023-08-14
- Lead Sponsor
- Central South University
- Target Recruit Count
- 59
- Registration Number
- NCT05840861
- Locations
- 🇨🇳
Mental Health Institute & Faculty of Psychiatry of The Second Xiangya Hospital, Central South University, Changsha, Hunan, China
Sequenced Treatment Alternatives to Relieve Adolescent Depression (STAR-AD)
- Conditions
- Interventions
- First Posted Date
- 2023-04-18
- Last Posted Date
- 2023-08-14
- Target Recruit Count
- 520
- Registration Number
- NCT05814640
- Locations
- 🇨🇳
The First Affiliated Hospital of Chongqing Medical University, Chongqing, Province, China
Vortioxetine Adjunctive Treatment in Bipolar Depression
- First Posted Date
- 2022-08-01
- Last Posted Date
- 2023-09-14
- Lead Sponsor
- First Affiliated Hospital of Zhejiang University
- Target Recruit Count
- 131
- Registration Number
- NCT05481957
- Locations
- 🇨🇳
Department of Psychiatry, First Affiliated Hospital of Zhejiang University, Hangzhou, Zhejiang, China
Vortioxetine as a Novel Anti-depressant With Improvement in Cognitive Abilities
- First Posted Date
- 2021-11-03
- Last Posted Date
- 2021-11-18
- Lead Sponsor
- Scotmann Pharmaceuticals
- Target Recruit Count
- 500
- Registration Number
- NCT05104918
Vortioxetine for Post-COVID-19 Condition
- Conditions
- Interventions
- First Posted Date
- 2021-09-17
- Last Posted Date
- 2023-05-11
- Lead Sponsor
- Brain and Cognition Discovery Foundation
- Target Recruit Count
- 200
- Registration Number
- NCT05047952
- Locations
- 🇨🇦
Brain and Cognition Discovery Foundation (BCDF), Toronto, Ontario, Canada
Vortioxetine to Prevent Return of Symptoms in Children With Depression
- First Posted Date
- 2021-08-20
- Last Posted Date
- 2023-01-05
- Lead Sponsor
- H. Lundbeck A/S
- Target Recruit Count
- 35
- Registration Number
- NCT05014919
- Locations
- 🇱🇻
Linda Keruze's Psychiatric Center, LLC, Liepaja, Latvia
🇺🇸AIM Trials, LLC, Plano, Texas, United States
🇷🇺Medicorehabilitation Research Center Phoenix, Rostov-On-Don, Rostov State, Russian Federation
Cognitive Effects of Adjuvant Vortioxetine in Early Schizophrenia
- Conditions
- Interventions
- First Posted Date
- 2021-05-20
- Last Posted Date
- 2024-02-26
- Target Recruit Count
- 37
- Registration Number
- NCT04895488
- Locations
- 🇪🇸
Hospital Universitario Virgen del Rocío, Sevilla, Spain
Vortioxetine for Treatment of Depressive Mood and Alcohol Use
- Conditions
- Interventions
- First Posted Date
- 2020-08-05
- Last Posted Date
- 2020-08-05
- Lead Sponsor
- Hanyang University Seoul Hospital
- Target Recruit Count
- 128
- Registration Number
- NCT04498897
- Locations
- 🇰🇷
Hanyang USH, Seoul, Korea, Republic of
Effect of Vortioxetine on Cognitive Symptoms in Patients With Schizophrenia
- First Posted Date
- 2020-07-02
- Last Posted Date
- 2020-07-02
- Lead Sponsor
- Alen Greš
- Target Recruit Count
- 120
- Registration Number
- NCT04456777
- Locations
- 🇭🇷
University Hospital Centre Zagreb, Zagreb, Croatia
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.