Cisplatin

Generic Name
Cisplatin
Brand Names
Platinol
Drug Type
Small Molecule
Chemical Formula
Cl2H6N2Pt
CAS Number
15663-27-1
Unique Ingredient Identifier
Q20Q21Q62J
Background

Cisplatin, cisplatinum or cis-diamminedichloroplatinum(II) (CDDP) is a platinum-based chemotherapy drug used to treat various types of cancers, including sarcomas, some carcinomas (e.g. small cell lung cancer, and ovarian cancer), lymphomas and germ cell tumors. It was the first member of its class, which now also includes carboplatin and oxaliplatin.

Indication

For the treatment of metastatic testicular tumors, metastatic ovarian tumors and advanced bladder cancer.

Associated Conditions
Advanced Ovarian Cancer, Ovarian Cancer Metastatic, Advanced Bladder cancer, Advanced Testicular cancer, Metastatic Testicular cancer
Associated Therapies
-

Chemotherapy Before Autologous Stem Cell Transplantation +/- Rituximab in Relapsed or Refractory Aggressive Non-Hodgkin's Lymphoma

First Posted Date
2004-03-09
Last Posted Date
2023-08-23
Lead Sponsor
NCIC Clinical Trials Group
Target Recruit Count
849
Registration Number
NCT00078949
Locations
🇨🇦

Allan Blair Cancer Centre, Regina, Saskatchewan, Canada

🇺🇸

Indiana University Medical Center, Indianapolis, Indiana, United States

🇺🇸

University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania, United States

and more 24 locations

Cisplatin or Carboplatin Combined With Gemcitabine in Locally Advanced, Recurrent, or Metastatic Malignant Salivary Gland Tumor

Phase 2
Completed
Conditions
First Posted Date
2004-03-09
Last Posted Date
2023-08-04
Lead Sponsor
NCIC Clinical Trials Group
Target Recruit Count
34
Registration Number
NCT00079079
Locations
🇨🇦

Princess Margaret Hospital, Toronto, Ontario, Canada

🇨🇦

CancerCare Manitoba, Winnipeg, Manitoba, Canada

🇨🇦

London Regional Cancer Program at London Health Sciences Centre, London, Ontario, Canada

and more 1 locations

Cisplatin, Etoposide, and Bevacizumab in Treating Patients With Previously Untreated Extensive Stage Small Cell Lung Cancer

First Posted Date
2004-03-09
Last Posted Date
2014-05-14
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
65
Registration Number
NCT00079040
Locations
🇺🇸

Eastern Cooperative Oncology Group, Boston, Massachusetts, United States

Bryostatin-1 Plus Cisplatin in Treating Patients With Recurrent or Advanced Cancer of the Cervix

Phase 2
Completed
Conditions
First Posted Date
2004-03-05
Last Posted Date
2013-07-10
Lead Sponsor
Icahn School of Medicine at Mount Sinai
Registration Number
NCT00005965
Locations
🇺🇸

Saint Vincent Catholic Medical Center of New York, New York, New York, United States

🇺🇸

NYU School of Medicine's Kaplan Comprehensive Cancer Center, New York, New York, United States

🇺🇸

New York Presbyterian Hospital - Cornell Campus, New York, New York, United States

and more 3 locations

SU5416, Irinotecan, and Cisplatin in Treating Patients With Advanced Solid Tumors

First Posted Date
2004-03-05
Last Posted Date
2013-01-31
Lead Sponsor
Ohio State University Comprehensive Cancer Center
Registration Number
NCT00006000
Locations
🇺🇸

Arthur G. James Cancer Hospital - Ohio State University, Columbus, Ohio, United States

Cisplatin Plus Gemcitabine in Treating Patients With Advanced Squamous Cell Head and Neck Cancer

Phase 2
Completed
Conditions
First Posted Date
2004-03-01
Last Posted Date
2013-04-17
Lead Sponsor
Fox Chase Cancer Center
Target Recruit Count
22
Registration Number
NCT00003264
Locations
🇺🇸

Delaware County Memorial Hospital, Drexel Hill, Pennsylvania, United States

🇺🇸

Reading Hospital and Medical Center, Reading, Pennsylvania, United States

🇺🇸

St. Francis Medical Center, Trenton, New Jersey, United States

and more 9 locations

Cisplatin and Gemcitabine Plus Trastuzumab in Treating Patients With Stage IIIB or Stage IV Non-Small Cell Lung Cancer

First Posted Date
2004-02-27
Last Posted Date
2018-10-26
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
22
Registration Number
NCT00016367
Locations
🇺🇸

University of Texas - MD Anderson Cancer Center, Houston, Texas, United States

Chemotherapy and Radiation Therapy in Treating Patients With Non-Small Cell Lung Cancer

Phase 1
Completed
Conditions
First Posted Date
2004-02-27
Last Posted Date
2013-09-02
Lead Sponsor
Fox Chase Cancer Center
Registration Number
NCT00022308
Locations
🇺🇸

Riverview Medical Center - Booker Cancer Center, Red Bank, New Jersey, United States

🇺🇸

Delaware County Memorial Hospital, Drexel Hill, Pennsylvania, United States

🇺🇸

Fox Chase Cancer Center, Philadelphia, Pennsylvania, United States

and more 5 locations

Combination Chemotherapy in Treating Patients With Metastatic Cancer of an Unknown Site of Origin

First Posted Date
2004-02-27
Last Posted Date
2013-09-20
Lead Sponsor
The Christie NHS Foundation Trust
Registration Number
NCT00022178
Locations
🇬🇧

Christie Hospital N.H.S. Trust, Manchester, England, United Kingdom

Standard Therapy Given With or Without Combination Chemotherapy in Treating Patients With Non-small Cell Lung Cancer

Phase 3
Conditions
First Posted Date
2004-02-20
Last Posted Date
2013-12-18
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
1800
Registration Number
NCT00003240
Locations
🇬🇧

Middlesex Hospital- Meyerstein Institute, London, England, United Kingdom

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