Cisplatin

Generic Name
Cisplatin
Brand Names
Platinol
Drug Type
Small Molecule
Chemical Formula
Cl2H6N2Pt
CAS Number
15663-27-1
Unique Ingredient Identifier
Q20Q21Q62J
Background

Cisplatin, cisplatinum or cis-diamminedichloroplatinum(II) (CDDP) is a platinum-based chemotherapy drug used to treat various types of cancers, including sarcomas, some carcinomas (e.g. small cell lung cancer, and ovarian cancer), lymphomas and germ cell tumors. It was the first member of its class, which now also includes carboplatin and oxaliplatin.

Indication

For the treatment of metastatic testicular tumors, metastatic ovarian tumors and advanced bladder cancer.

Associated Conditions
Advanced Ovarian Cancer, Ovarian Cancer Metastatic, Advanced Bladder cancer, Advanced Testicular cancer, Metastatic Testicular cancer
Associated Therapies
-

Docetaxel and Cisplatin With or Without Dimesna in Treating Patients With Stage IIIB or Stage IV Non-Small Cell Lung Cancer

First Posted Date
2004-02-12
Last Posted Date
2016-06-30
Lead Sponsor
Alliance for Clinical Trials in Oncology
Target Recruit Count
160
Registration Number
NCT00077311
Locations
🇺🇸

Graham Hospital, Canton, Illinois, United States

🇺🇸

Greenebaum Cancer Center at University of Maryland Medical Center, Baltimore, Maryland, United States

🇺🇸

Veterans Affairs Medical Center - Baltimore, Baltimore, Maryland, United States

and more 61 locations

Induction Chemotherapy Using Doxorubicin and Cisplatin Followed by Combretastatin A4 Phosphate and Radiation Therapy in Treating Patients With Newly Diagnosed Regionally Advanced Anaplastic Thyroid Cancer

Phase 1
Terminated
Conditions
First Posted Date
2004-02-11
Last Posted Date
2010-06-11
Lead Sponsor
Case Comprehensive Cancer Center
Target Recruit Count
4
Registration Number
NCT00077103
Locations
🇺🇸

Josephine Ford Cancer Center at Henry Ford Hospital, Detroit, Michigan, United States

🇺🇸

Ireland Cancer Center at University Hosptials Case Medical Center, Case Comprehensive Cancer Center, Cleveland, Ohio, United States

🇺🇸

Hillman Cancer Center at University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania, United States

Cytochlor and Tetrahydrouridine as Radiosensitizers and Cisplatin Combined With Radiation Therapy in Treating Patients With Advanced Squamous Cell Carcinoma of the Oral Cavity (Mouth) or Oropharynx (Throat)

First Posted Date
2004-02-11
Last Posted Date
2016-12-15
Lead Sponsor
University of Miami
Target Recruit Count
1
Registration Number
NCT00077051
Locations
🇺🇸

University of Miami Sylvester Comprehensive Cancer Center, Miami, Florida, United States

Cisplatin Plus Bryostatin 1 in Treating Patients With Advanced Cancer

First Posted Date
2004-02-09
Last Posted Date
2013-07-18
Lead Sponsor
Lombardi Comprehensive Cancer Center
Registration Number
NCT00003108
Locations
🇺🇸

Lombardi Cancer Center, Washington, District of Columbia, United States

Repeated Bone Marrow Transplantation in Treating Women With Advanced Breast Cancer

Phase 1
Terminated
Conditions
First Posted Date
2004-02-09
Last Posted Date
2020-07-14
Lead Sponsor
Louisiana State University Health Sciences Center Shreveport
Target Recruit Count
12
Registration Number
NCT00003086
Locations
🇺🇸

Louisiana State University School of Medicine, Shreveport, Louisiana, United States

Combination Chemotherapy Plus Dexrazoxane in Treating Patients With Newly Diagnosed Nonmetastatic Osteosarcoma

First Posted Date
2004-02-09
Last Posted Date
2014-08-05
Lead Sponsor
Children's Oncology Group
Target Recruit Count
253
Registration Number
NCT00003937
Locations
🇺🇸

St. Christopher's Hospital for Children, Philadelphia, Pennsylvania, United States

🇺🇸

Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States

🇺🇸

Massachusetts General Hospital Cancer Center, Boston, Massachusetts, United States

and more 145 locations

Tirapazamine Plus Cisplatin in Treating Patients With Persistent or Recurrent Ovarian Epithelial or Primary Peritoneal Cancer

First Posted Date
2004-02-04
Last Posted Date
2012-01-10
Lead Sponsor
Gynecologic Oncology Group
Registration Number
NCT00020696
Locations
🇺🇸

Cleveland Clinic Taussig Cancer Center, Cleveland, Ohio, United States

🇺🇸

Arthur G. James Cancer Hospital - Ohio State University, Columbus, Ohio, United States

🇺🇸

University of Pennsylvania Cancer Center, Philadelphia, Pennsylvania, United States

and more 51 locations

Surgery Plus Combination Chemotherapy and Radiation Therapy in Treating Patients With Cancer of the Urinary Tract

First Posted Date
2004-02-03
Last Posted Date
2021-02-21
Lead Sponsor
UNICANCER
Target Recruit Count
53
Registration Number
NCT00006111
Locations
🇫🇷

Centre Oscar Lambret, Lille, France

🇫🇷

Centre Leon Berard, Lyon, France

🇫🇷

Institut Sainte Catherine, Avignon, France

and more 8 locations

Radiation Therapy Plus Combination Chemotherapy in Treating Patients With Small Cell Lung Cancer

First Posted Date
2004-01-29
Last Posted Date
2013-11-03
Lead Sponsor
Radiation Therapy Oncology Group
Target Recruit Count
64
Registration Number
NCT00005022
Locations
🇺🇸

Northwest Community Hospital, Arlington Heights, Illinois, United States

🇺🇸

Northwestern Memorial Hospital, Chicago, Illinois, United States

🇺🇸

University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania, United States

and more 259 locations

Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Advanced Head and Neck Cancer

Phase 3
Completed
Conditions
First Posted Date
2004-01-29
Last Posted Date
2018-07-09
Lead Sponsor
European Organisation for Research and Treatment of Cancer - EORTC
Target Recruit Count
359
Registration Number
NCT00003888
Locations

Institute of Oncology and Radiology of Serbia, Belgrade, Former Yugoslavia

🇫🇷

CHR de Besancon - Hopital Jean Minjoz, Besancon, France

🇫🇷

Centre Hospital Regional Universitaire de Limoges, Limoges, France

and more 41 locations
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