Cisplatin

Generic Name
Cisplatin
Brand Names
Platinol
Drug Type
Small Molecule
Chemical Formula
Cl2H6N2Pt
CAS Number
15663-27-1
Unique Ingredient Identifier
Q20Q21Q62J
Background

Cisplatin, cisplatinum or cis-diamminedichloroplatinum(II) (CDDP) is a platinum-based chemotherapy drug used to treat various types of cancers, including sarcomas, some carcinomas (e.g. small cell lung cancer, and ovarian cancer), lymphomas and germ cell tumors. It was the first member of its class, which now also includes carboplatin and oxaliplatin.

Indication

For the treatment of metastatic testicular tumors, metastatic ovarian tumors and advanced bladder cancer.

Associated Conditions
Advanced Ovarian Cancer, Ovarian Cancer Metastatic, Advanced Bladder cancer, Advanced Testicular cancer, Metastatic Testicular cancer
Associated Therapies
-

Gemcitabine Plus Radiation Therapy or Combination Chemotherapy in Treating Patients With Non-small Cell Lung Cancer

Phase 1
Completed
Conditions
First Posted Date
2003-11-26
Last Posted Date
2018-08-10
Lead Sponsor
Wake Forest University Health Sciences
Target Recruit Count
40
Registration Number
NCT00003202
Locations
🇺🇸

Comprehensive Cancer Center at Wake Forest University, Winston-Salem, North Carolina, United States

Combination Chemotherapy as Induction Therapy in Treating Patients With Stage III Non-small Cell Lung Cancer

Phase 1
Completed
Conditions
First Posted Date
2003-11-25
Last Posted Date
2013-06-27
Lead Sponsor
Memorial Sloan Kettering Cancer Center
Registration Number
NCT00003037
Locations
🇺🇸

Memorial Sloan-Kettering Cancer Center, New York, New York, United States

Filgrastim Plus Chemotherapy Compared With Filgrastim Alone In Treating Women Undergoing Peripheral Stem Cell Transplantation For Breast Cancer

First Posted Date
2003-11-24
Last Posted Date
2018-11-06
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
184
Registration Number
NCT00002836
Locations
🇺🇸

University of Texas - MD Anderson Cancer Center, Houston, Texas, United States

Phase 1/2 Study of S-1 and Cisplatin in Advanced Gastric Cancer

Phase 1
Completed
Conditions
First Posted Date
2003-11-13
Last Posted Date
2024-06-26
Lead Sponsor
Taiho Oncology, Inc.
Target Recruit Count
41
Registration Number
NCT00072787
Locations
🇺🇸

Lovelace Sandia Health System, Albuquerque, New Mexico, United States

🇺🇸

University of New Mexico - Albuquerque, Albuquerque, New Mexico, United States

🇺🇸

New Mexico VA Health Care System, Albuquerque, New Mexico, United States

and more 8 locations

Edotecarin and Cisplatin in Treating Patients With Advanced or Metastatic Solid Tumors

First Posted Date
2003-11-06
Last Posted Date
2013-12-19
Lead Sponsor
Memorial Sloan Kettering Cancer Center
Registration Number
NCT00072332
Locations
🇺🇸

Memorial Sloan-Kettering Cancer Center, New York, New York, United States

Dacarbazine and/or Cisplatin Compared With Complete Metastasectomy in Treating Patients With Stage IV Melanoma

Phase 3
Completed
Conditions
First Posted Date
2003-11-06
Last Posted Date
2013-06-19
Lead Sponsor
National Cancer Institute (NCI)
Registration Number
NCT00072124
Locations
🇺🇸

Warren Grant Magnuson Clinical Center - NCI Clinical Studies Support, Bethesda, Maryland, United States

Cisplatin and Ifosfamide Combined With Either Paclitaxel or Vinblastine in Treating Men With Progressive or Recurrent Metastatic Germ Cell Tumors

First Posted Date
2003-11-06
Last Posted Date
2016-07-04
Lead Sponsor
Alliance for Clinical Trials in Oncology
Target Recruit Count
1
Registration Number
NCT00072215
Locations
🇺🇸

Broward General Medical Center, Fort Lauderdale, Florida, United States

🇺🇸

Memorial Cancer Institute at Memorial Regional Hospital, Hollywood, Florida, United States

🇺🇸

Palm Beach Cancer Institute - West Palm Beach, West Palm Beach, Florida, United States

and more 76 locations

Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Infants With Malignant Brain or Spinal Cord Tumors

First Posted Date
2003-11-06
Last Posted Date
2014-03-28
Lead Sponsor
Children's Oncology Group
Target Recruit Count
94
Registration Number
NCT00003141
Locations
🇺🇸

Childrens Hospital Los Angeles, Los Angeles, California, United States

🇺🇸

Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States

🇺🇸

Children's Hospital of Pittsburgh of UPMC, Pittsburgh, Pennsylvania, United States

and more 68 locations

Cisplatin and Irinotecan Followed by Carboplatin, Etoposide, and Radiation Therapy in Treating Patients With Limited-Stage Small Cell Lung Cancer

First Posted Date
2003-11-05
Last Posted Date
2016-07-06
Lead Sponsor
Alliance for Clinical Trials in Oncology
Target Recruit Count
78
Registration Number
NCT00072527
Locations
🇺🇸

McDonough District Hospital, Macomb, Illinois, United States

🇺🇸

Hudner Oncology Center at Saint Anne's Hospital, Fall River, Massachusetts, United States

🇺🇸

Saint Luke's Hospital, Chesterfield, Missouri, United States

and more 73 locations

Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Children With Newly Diagnosed Neuroblastoma

First Posted Date
2003-10-09
Last Posted Date
2014-02-13
Lead Sponsor
Children's Oncology Group
Target Recruit Count
42
Registration Number
NCT00017368
Locations
🇺🇸

CCOP - Columbia River Oncology Program, Portland, Oregon, United States

🇺🇸

Floating Hospital for Children, Boston, Massachusetts, United States

🇺🇸

CCOP - Marshfield Clinic Research Foundation, Marshfield, Wisconsin, United States

and more 6 locations
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