Cisplatin

Generic Name
Cisplatin
Brand Names
Platinol
Drug Type
Small Molecule
Chemical Formula
Cl2H6N2Pt
CAS Number
15663-27-1
Unique Ingredient Identifier
Q20Q21Q62J
Background

Cisplatin, cisplatinum or cis-diamminedichloroplatinum(II) (CDDP) is a platinum-based chemotherapy drug used to treat various types of cancers, including sarcomas, some carcinomas (e.g. small cell lung cancer, and ovarian cancer), lymphomas and germ cell tumors. It was the first member of its class, which now also includes carboplatin and oxaliplatin.

Indication

For the treatment of metastatic testicular tumors, metastatic ovarian tumors and advanced bladder cancer.

Associated Conditions
Advanced Ovarian Cancer, Ovarian Cancer Metastatic, Advanced Bladder cancer, Advanced Testicular cancer, Metastatic Testicular cancer
Associated Therapies
-

Chemoembolization in Treating Patients With Primary Liver Cancer or Metastases to the Liver

First Posted Date
2003-10-09
Last Posted Date
2023-07-05
Lead Sponsor
Eastern Cooperative Oncology Group
Target Recruit Count
50
Registration Number
NCT00003907
Locations
🇺🇸

Rush-Copley Cancer Care Center, Aurora, Illinois, United States

🇺🇸

Veterans Affairs Medical Center - Atlanta (Decatur), Decatur, Georgia, United States

🇺🇸

Borgess Medical Center, Kalamazoo, Michigan, United States

and more 34 locations

Gemcitabine and Cisplatin in Treating Patients With Refractory or Recurrent Cancer of the Cervix

Phase 2
Terminated
Conditions
First Posted Date
2003-10-08
Last Posted Date
2013-04-11
Lead Sponsor
Gynecologic Oncology Group
Registration Number
NCT00006482
Locations
🇺🇸

Rush-Presbyterian-St. Luke's Medical Center, Chicago, Illinois, United States

🇺🇸

Tufts University School of Medicine, Boston, Massachusetts, United States

🇺🇸

Ireland Cancer Center, Cleveland, Ohio, United States

and more 31 locations

Combination Chemotherapy and Radiation Therapy in Treating Patients With Limited-Stage Small Cell Lung Cancer

First Posted Date
2003-10-08
Last Posted Date
2016-07-06
Lead Sponsor
Alliance for Clinical Trials in Oncology
Target Recruit Count
73
Registration Number
NCT00006012
Locations
🇺🇸

Galesburg Cottage Hospital, Galesburg, Illinois, United States

🇺🇸

Siouxland Regional Cancer Center, Sioux City, Iowa, United States

🇺🇸

St. Elizabeth Regional Medical Center, Lincoln, Nebraska, United States

and more 81 locations

Pixantrone, Cytarabine, Methylprednisolone, and Cisplatin in Treating Patients With Aggressive Non-Hodgkin's Lymphoma in First Relapse

Phase 2
Conditions
First Posted Date
2003-10-07
Last Posted Date
2009-07-07
Lead Sponsor
Theradex
Registration Number
NCT00069966
Locations
🇺🇸

Massachusetts General Hospital Cancer Center, Boston, Massachusetts, United States

🇺🇸

Baylor University Medical Center, Dallas, Texas, United States

🇺🇸

Ireland Cancer Center at University Hospitals of Cleveland and Case Western Reserve University, Cleveland, Ohio, United States

and more 26 locations

Induction Chemotherapy Using Cyclophosphamide and Topotecan in Treating Patients Who Are Undergoing Autologous Peripheral Stem Cell Transplantation for Newly Diagnosed or Progressive Neuroblastoma

First Posted Date
2003-10-07
Last Posted Date
2014-02-13
Lead Sponsor
Children's Oncology Group
Target Recruit Count
31
Registration Number
NCT00070200
Locations
🇺🇸

Children's Hospital and Regional Medical Center - Seattle, Seattle, Washington, United States

🇺🇸

Children's Memorial Hospital - Chicago, Chicago, Illinois, United States

🇦🇺

Westmead Hospital, Westmead, New South Wales, Australia

and more 3 locations

Combination Chemotherapy Followed By Chemoradiotherapy, With or Without Surgery, in Treating Patients With Resectable Locally Advanced Cancer of the Esophagus or Gastroesophageal Junction

First Posted Date
2003-10-07
Last Posted Date
2017-02-17
Lead Sponsor
Radiation Therapy Oncology Group
Target Recruit Count
43
Registration Number
NCT00069953
Locations
🇺🇸

Providence Saint Joseph Medical Center - Burbank, Burbank, California, United States

🇺🇸

Hubert H. Humphrey Cancer Center at North Memorial Medical Center, Robbinsdale, Minnesota, United States

🇺🇸

Fox Chase Cancer Center, Philadelphia, Pennsylvania, United States

and more 94 locations

A Study With Gemcitabine, Cisplatin, and LY293111 in Non-Small Cell Lung Cancer

Phase 2
Completed
Conditions
First Posted Date
2003-10-06
Last Posted Date
2007-12-21
Lead Sponsor
Eli Lilly and Company
Target Recruit Count
195
Registration Number
NCT00069875
Locations
🇨🇦

For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon-Fri from 9AM to 5PM Eastern time (UTC/GMT - 5 hours, EST) or speak with your personal physician, Montreal, Quebec, Canada

🇪🇸

For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Monday-Friday from 9:00 AM to 5:00 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician, Madrid, Spain

Radiation Therapy and Combination Chemotherapy in Treating Patients With Stage II or Stage III Bladder Cancer

First Posted Date
2003-09-30
Last Posted Date
2020-10-20
Lead Sponsor
Radiation Therapy Oncology Group
Target Recruit Count
84
Registration Number
NCT00003930
Locations
🇺🇸

Sinai Hospital of Baltimore, Baltimore, Maryland, United States

🇺🇸

Ireland Cancer Center, Cleveland, Ohio, United States

🇺🇸

Huntsville Hospital System, Huntsville, Alabama, United States

and more 226 locations

Combination Chemotherapy in Treating Patients With Germ Cell Tumors That Have Not Responded to Previous Cisplatin

First Posted Date
2003-09-18
Last Posted Date
2013-07-02
Lead Sponsor
Memorial Sloan Kettering Cancer Center
Target Recruit Count
43
Registration Number
NCT00002559
Locations
🇺🇸

Memorial Sloan-Kettering Cancer Center, New York, New York, United States

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