Cisplatin

Generic Name
Cisplatin
Brand Names
Platinol
Drug Type
Small Molecule
Chemical Formula
Cl2H6N2Pt
CAS Number
15663-27-1
Unique Ingredient Identifier
Q20Q21Q62J
Background

Cisplatin, cisplatinum or cis-diamminedichloroplatinum(II) (CDDP) is a platinum-based chemotherapy drug used to treat various types of cancers, including sarcomas, some carcinomas (e.g. small cell lung cancer, and ovarian cancer), lymphomas and germ cell tumors. It was the first member of its class, which now also includes carboplatin and oxaliplatin.

Indication

For the treatment of metastatic testicular tumors, metastatic ovarian tumors and advanced bladder cancer.

Associated Conditions
Advanced Ovarian Cancer, Ovarian Cancer Metastatic, Advanced Bladder cancer, Advanced Testicular cancer, Metastatic Testicular cancer
Associated Therapies
-

Radiation Therapy, Mitomycin, and Either Fluorouracil or Cisplatin in Treating Patients With Locally Advanced Anal Cancer

Phase 2
Terminated
Conditions
First Posted Date
2003-09-11
Last Posted Date
2012-09-24
Lead Sponsor
European Organisation for Research and Treatment of Cancer - EORTC
Target Recruit Count
88
Registration Number
NCT00068744
Locations
🇷🇸

Institute of Oncology and Radiology of Serbia, Belgrade, Serbia

🇧🇪

Ziekenhuis Netwerk Antwerpen Middelheim, Antwerpen, Belgium

🇧🇪

Cazk Groeninghe - Campus Maria's Voorzienigheid, Kortrijk, Belgium

and more 21 locations

Chemotherapy, Interferon Alfa, and Radiation Therapy in Treating Patients Who Have Undergone Surgery For Pancreatic Cancer

First Posted Date
2003-09-11
Last Posted Date
2012-02-15
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
29
Registration Number
NCT00068575
Locations
🇺🇸

M. D. Anderson Cancer Center at University of Texas, Houston, Texas, United States

Chemotherapy, Radiation Therapy, and Surgery in Treating Patients With Locally Advanced Cancer of the Vulva

First Posted Date
2003-09-11
Last Posted Date
2017-11-20
Lead Sponsor
Gynecologic Oncology Group
Target Recruit Count
61
Registration Number
NCT00068406
Locations
🇺🇸

Case Western Reserve University, Cleveland, Ohio, United States

🇺🇸

Cleveland Clinic Cancer Center/Fairview Hospital, Cleveland, Ohio, United States

🇺🇸

Gynecologic Oncology of Indiana, Indianapolis, Indiana, United States

and more 100 locations

Combination Chemotherapy Compared With Hormone Therapy in Treating Patients With Recurrent, Stage III, or Stage IV Endometrial Cancer

Phase 3
Terminated
Conditions
First Posted Date
2003-09-09
Last Posted Date
2013-04-11
Lead Sponsor
Gynecologic Oncology Group
Registration Number
NCT00016341
Locations
🇺🇸

Jonsson Comprehensive Cancer Center, UCLA, Los Angeles, California, United States

🇺🇸

Rush-Presbyterian-St. Luke's Medical Center, Chicago, Illinois, United States

🇺🇸

Arthur G. James Cancer Hospital - Ohio State University, Columbus, Ohio, United States

and more 47 locations

3-AP Plus Cisplatin and Paclitaxel in Treating Patients With Advanced or Metastatic Cancer

First Posted Date
2003-09-09
Last Posted Date
2013-07-18
Lead Sponsor
Vion Pharmaceuticals
Registration Number
NCT00016874
Locations
🇺🇸

Albert Einstein Comprehensive Cancer Center, Bronx, New York, United States

🇺🇸

New York Presbyterian Hospital - Cornell Campus, New York, New York, United States

Radiation Therapy With or Without Cisplatin in Treating Patients With Stage I, Stage II, or Stage III Cancer of the Vulva

Phase 3
Terminated
Conditions
First Posted Date
2003-09-03
Last Posted Date
2013-06-10
Lead Sponsor
Gynecologic Oncology Group
Registration Number
NCT00006096
Locations
🇺🇸

University of Mississippi Medical Center, Jackson, Mississippi, United States

🇺🇸

Cleveland Clinic Taussig Cancer Center, Cleveland, Ohio, United States

🇺🇸

Arthur G. James Cancer Hospital - Ohio State University, Columbus, Ohio, United States

and more 27 locations

Irinotecan and Cisplatin in Treating Patients With Locally Advanced or Metastatic Penile Cancer

Phase 2
Completed
Conditions
First Posted Date
2003-08-07
Last Posted Date
2012-09-24
Lead Sponsor
European Organisation for Research and Treatment of Cancer - EORTC
Registration Number
NCT00066391
Locations
🇬🇧

Bristol Haematology and Oncology Centre, Bristol, England, United Kingdom

🇧🇪

U.Z. Gasthuisberg, Leuven, Belgium

🇭🇺

National Institute of Oncology, Budapest, Hungary

and more 5 locations

Tirapazamine Combined With Chemo and RT in Limited-Stage Small Cell Lung Cancer

First Posted Date
2003-08-07
Last Posted Date
2014-05-15
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
72
Registration Number
NCT00066742
Locations
🇺🇸

Southwest Oncology Group (SWOG) Research Base, San Antonio, Texas, United States

Combination Chemotherapy in Treating Children With Newly Diagnosed Malignant Germ Cell Tumors

First Posted Date
2003-08-07
Last Posted Date
2013-10-17
Lead Sponsor
Children's Oncology Group
Target Recruit Count
19
Registration Number
NCT00066482
Locations
🇺🇸

Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States

🇺🇸

Medical City Dallas Hospital, Dallas, Texas, United States

🇺🇸

Children's Memorial Hospital - Chicago, Chicago, Illinois, United States

and more 95 locations

Cisplatin, Etoposide, and Radiation Therapy in Treating Patients With Limited-Stage Small Cell Lung Cancer

First Posted Date
2003-08-07
Last Posted Date
2017-12-22
Lead Sponsor
Radiation Therapy Oncology Group
Target Recruit Count
72
Registration Number
NCT00066222
Locations
🇺🇸

Howard Community Hospital at Howard Regional Health System, Kokomo, Indiana, United States

🇺🇸

Kewanee Hospital, Kewanee, Illinois, United States

🇺🇸

OSF St. Francis Medical Center, Peoria, Illinois, United States

and more 101 locations
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