Cisplatin

Generic Name
Cisplatin
Brand Names
Platinol
Drug Type
Small Molecule
Chemical Formula
Cl2H6N2Pt
CAS Number
15663-27-1
Unique Ingredient Identifier
Q20Q21Q62J
Background

Cisplatin, cisplatinum or cis-diamminedichloroplatinum(II) (CDDP) is a platinum-based chemotherapy drug used to treat various types of cancers, including sarcomas, some carcinomas (e.g. small cell lung cancer, and ovarian cancer), lymphomas and germ cell tumors. It was the first member of its class, which now also includes carboplatin and oxaliplatin.

Indication

For the treatment of metastatic testicular tumors, metastatic ovarian tumors and advanced bladder cancer.

Associated Conditions
Advanced Ovarian Cancer, Ovarian Cancer Metastatic, Advanced Bladder cancer, Advanced Testicular cancer, Metastatic Testicular cancer
Associated Therapies
-

Cisplatin Plus Etoposide With or Without Paclitaxel in Treating Patients With Extensive-Stage Small Cell Lung Cancer

Phase 3
Completed
Conditions
Interventions
First Posted Date
2004-02-20
Last Posted Date
2016-07-20
Lead Sponsor
Alliance for Clinical Trials in Oncology
Target Recruit Count
587
Registration Number
NCT00003299
Locations
🇺🇸

CCOP - Illinois Oncology Research Association, Peoria, Illinois, United States

🇺🇸

CCOP - Carle Cancer Center, Urbana, Illinois, United States

🇺🇸

CCOP - Iowa Oncology Research Association, Des Moines, Iowa, United States

and more 17 locations

Etoposide Plus Radiation Therapy Followed by Combination Chemotherapy in Treating Children With Newly Diagnosed Advanced Medulloblastoma

First Posted Date
2004-02-20
Last Posted Date
2014-07-25
Lead Sponsor
Children's Oncology Group
Target Recruit Count
53
Registration Number
NCT00003573
Locations
🇺🇸

Hope Children's Hospital, Oak Lawn, Illinois, United States

🇺🇸

Arizona Cancer Center, Tucson, Arizona, United States

🇺🇸

Saint Jude Midwest Affiliate, Peoria, Illinois, United States

and more 103 locations

Combination Chemotherapy in Treating Patients With Locally Advanced or Metastatic Solid Tumors

First Posted Date
2004-02-16
Last Posted Date
2013-12-19
Lead Sponsor
Memorial Sloan Kettering Cancer Center
Registration Number
NCT00005791
Locations
🇺🇸

Memorial Sloan-Kettering Cancer Center, New York, New York, United States

Cisplatin Plus Vinorelbine With or Without Tirapazamine in Treating Patients With Stage IIIB or Stage IV Non-Small Cell Lung Cancer

Phase 3
Completed
Conditions
First Posted Date
2004-02-16
Last Posted Date
2013-08-02
Lead Sponsor
Sanofi
Registration Number
NCT00017459
Locations
🇺🇸

University of Florida Health Science Center - Jacksonville, Jacksonville, Florida, United States

🇺🇸

Los Angeles County Harbor-UCLA Medical Center, Torrance, California, United States

🇺🇸

John Wayne Cancer Institute, Santa Monica, California, United States

and more 39 locations

Radiation Therapy, Combination Chemotherapy, and Amifostine in Treating Patients With Head and Neck Cancer

First Posted Date
2004-02-16
Last Posted Date
2016-12-15
Lead Sponsor
University of Miami
Target Recruit Count
36
Registration Number
NCT00003582
Locations
🇺🇸

Sylvester Cancer Center, University of Miami, Miami, Florida, United States

3-AP Plus Cisplatin in Treating Patients With Recurrent or Metastatic Adenocarcinoma of the Esophagus or Gastroesophageal Junction

First Posted Date
2004-02-12
Last Posted Date
2013-10-08
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
39
Registration Number
NCT00077545
Locations
🇺🇸

University of Chicago Comprehensive Cancer Center, Chicago, Illinois, United States

Combination Chemotherapy in Treating Patients With Stage III or Stage IV Pancreatic Cancer That Cannot Be Removed by Surgery

Phase 2
Completed
Conditions
First Posted Date
2004-02-12
Last Posted Date
2013-04-05
Lead Sponsor
Barbara Ann Karmanos Cancer Institute
Target Recruit Count
30
Registration Number
NCT00004003
Locations
🇺🇸

Barbara Ann Karmanos Cancer Institute, Detroit, Michigan, United States

Irinotecan and Cisplatin With or Without Amifostine in Treating Children With Solid Tumors That Have Not Responded to Previous Therapy

First Posted Date
2004-02-12
Last Posted Date
2013-07-02
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
30
Registration Number
NCT00004919
Locations
🇺🇸

COG Phase I Consortium, Arcadia, California, United States

Combination Chemotherapy Followed by Surgery and Intraperitoneal Chemotherapy in Treating Patients With Locally Advanced Stomach Cancer

Phase 2
Completed
Conditions
First Posted Date
2004-02-12
Last Posted Date
2013-06-19
Lead Sponsor
Memorial Sloan Kettering Cancer Center
Registration Number
NCT00006038
Locations
🇺🇸

Memorial Sloan-Kettering Cancer Center, New York, New York, United States

Intensive Neoadjuvant Chemotherapy in Treating Young Patients Undergoing Surgical Resection for High-Risk Hepatoblastoma

Phase 2
Conditions
First Posted Date
2004-02-12
Last Posted Date
2014-06-24
Lead Sponsor
University of Leicester
Target Recruit Count
57
Registration Number
NCT00077389
Locations
🇬🇧

Addenbrooke's Hospital, Cambridge, England, United Kingdom

🇬🇧

Middlesex Hospital, London, England, United Kingdom

🇬🇧

Children's Cancer and Leukaemia Group, Leicester, England, United Kingdom

and more 20 locations
© Copyright 2024. All Rights Reserved by MedPath