Bismuth subsalicylate
- Generic Name
- Bismuth subsalicylate
- Brand Names
- Diphen, Kaopectate Reformulated Aug 2006, Kola-pectin, Pepto-bismol, Percy Medicine
- Drug Type
- Small Molecule
- Chemical Formula
- C7H5BiO4
- CAS Number
- 14882-18-9
- Unique Ingredient Identifier
- 62TEY51RR1
- Background
Bismuth subsalicylate is an antacid and anti-diarrheal agent. Exhibiting antibacterial and gastroprotective properties, bismuth subsalicylate is an insoluble salt of salicylic acid linked to trivalent bismuth cation. Each molecule of bismuth subsalicylate contains 58% bismuth and 42% salicylate by weight. Bismuth subsalicylate has been around for over 100 ye...
- Indication
Bismuth subsalicylate is indicated to temporarily relieve diarrhea, travelers' diarrhea, and upset stomach due to overindulgence in food and drink, including heartburn, indigestion, nausea, gas, belching, and fullness.
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- Associated Conditions
- Diarrhea, Dyspepsia, Flatulence, Heartburn, Helicobacter Pylori Infection, Nausea, Traveler's Diarrhea, Upset stomach, Belching, Gastrointestinal fullness
- Associated Therapies
- -
Effect of Bismuth Subsalicylate on the Gut Microbiome and Host Response in Healthy Adults
- First Posted Date
- 2023-07-05
- Last Posted Date
- 2024-10-03
- Target Recruit Count
- 40
- Registration Number
- NCT05930197
- Locations
- 🇺🇸
National Institutes of Health Clinical Center, Bethesda, Maryland, United States
THE EFFECT OF HELICOBACTER PYLORI ERADICATION THERAPY TO GASTRIC WALL THICKNESS BEFORE THE LAPAROSCOPIC SLEEVE GASTRECTOMY
- Conditions
- Interventions
- First Posted Date
- 2018-11-29
- Last Posted Date
- 2021-03-23
- Target Recruit Count
- 3
- Registration Number
- NCT03757650
- Locations
- 🇹🇷
Fatih Sultan Mehmet Research and Training Hospital, Istanbul, Turkey
Use of Bismuth Subsalicylate in Clostridium Difficile Colitis
- Conditions
- Interventions
- First Posted Date
- 2018-07-19
- Last Posted Date
- 2018-07-19
- Lead Sponsor
- Bassett Healthcare
- Registration Number
- NCT03592082
- Locations
- 🇺🇸
Bassett Healthcare Network, Cooperstown, New York, United States
Bismuth Subsalicylate's Role in the Prevention of Travelers' Diarrhea
- Conditions
- Interventions
- First Posted Date
- 2018-05-24
- Last Posted Date
- 2024-04-09
- Lead Sponsor
- Centers for Disease Control and Prevention
- Target Recruit Count
- 281
- Registration Number
- NCT03535272
- Locations
- 🇺🇸
Marina Rogova, New York, New York, United States
Impact of Bismuth Subsalicylate on Antimicrobial Use Among Adult Diarrhea Outpatients--Pakistan
- First Posted Date
- 2014-01-28
- Last Posted Date
- 2019-01-30
- Lead Sponsor
- Centers for Disease Control and Prevention
- Target Recruit Count
- 400
- Registration Number
- NCT02047162
- Locations
- 🇵🇰
HOPE, Karachi, Pakistan
Levofloxacin and Bismuth-containing Therapy Versus Quadruple Therapy as Second-line Treatment of Resistant Helicobacter Pylori Infection
- First Posted Date
- 2012-12-05
- Last Posted Date
- 2014-08-29
- Lead Sponsor
- Shanghai Jiao Tong University School of Medicine
- Target Recruit Count
- 200
- Registration Number
- NCT01742429
- Locations
- 🇨🇳
Renji Hospital, Shanghai Jiao-Tong University School of Medicine, Shanghai, Shanghai, China
Antibiotic Therapy and Antacids in Patients With Malt Lymphoma of the Stomach
- Conditions
- Interventions
- First Posted Date
- 2004-06-10
- Last Posted Date
- 2018-10-24
- Lead Sponsor
- M.D. Anderson Cancer Center
- Target Recruit Count
- 5
- Registration Number
- NCT00002682
- Locations
- 🇺🇸
University of Texas - MD Anderson Cancer Center, Houston, Texas, United States
🇺🇸MD Anderson Cancer Center Orlando, Orlando, Florida, United States
Drug Development Updates
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