Gabapentin

Generic Name
Gabapentin
Brand Names
Gralise, Neurontin
Drug Type
Small Molecule
Chemical Formula
C9H17NO2
CAS Number
60142-96-3
Unique Ingredient Identifier
6CW7F3G59X
Background

Gabapentin is a structural analogue of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) that was first approved for use in the United States in 1993. It was originally developed as a novel anti-epileptic for the treatment of certain types of seizures - today it is also widely used to treat neuropathic pain. Gabapentin has some stark advantages ...

Indication

In the United States, gabapentin is officially indicated for the treatment of postherpetic neuralgia in adults and for the adjunctive treatment of partial-onset seizures, with or without secondary generalization, in patients 3 years of age and older. In Europe, gabapentin is indicated for adjunctive therapy in the treatment of partial-onset seizures, with or...

Associated Conditions
Partial-Onset Seizures, Peripheral Neuropathic Pain, Postherpetic Neuralgia
Associated Therapies
-

Nonopioid Analgesia After Anterior Cruciate Ligament Reconstruction

First Posted Date
2019-01-28
Last Posted Date
2021-02-11
Lead Sponsor
Henry Ford Health System
Target Recruit Count
62
Registration Number
NCT03818932
Locations
🇺🇸

Henry Ford Health System, Detroit, Michigan, United States

Nonopioid Analgesia After Rotator Cuff Repair

First Posted Date
2019-01-28
Last Posted Date
2024-04-02
Lead Sponsor
Henry Ford Health System
Target Recruit Count
70
Registration Number
NCT03818919
Locations
🇺🇸

Health Ford Health System, Detroit, Michigan, United States

DIalysis Symptom COntrol-Restless Legs Syndrome Trial

First Posted Date
2019-01-16
Last Posted Date
2022-09-21
Lead Sponsor
Population Health Research Institute
Target Recruit Count
52
Registration Number
NCT03806530
Locations
🇨🇦

The Ottawa Hospital, Ottawa, Ontario, Canada

🇨🇦

St. Joseph's Hamilton Healthcare, Hamilton, Ontario, Canada

🇨🇦

Nova Scotia Health Authority, Halifax, Nova Scotia, Canada

Comparison of Gabapentin With Doxepin in the Management of Uremic Pruritus

Phase 4
Completed
Conditions
Interventions
First Posted Date
2018-11-29
Last Posted Date
2018-11-29
Lead Sponsor
University of Balamand
Target Recruit Count
14
Registration Number
NCT03758079
Locations
🇱🇧

Saint George Hospital University Medical Center, Beirut, Lebanon

Trazodone/Gabapentin Fixed Dose Combination Products in Painful Diabetic Neuropathy

First Posted Date
2018-11-21
Last Posted Date
2021-05-27
Lead Sponsor
Aziende Chimiche Riunite Angelini Francesco S.p.A
Target Recruit Count
240
Registration Number
NCT03749642
Locations
🇨🇿

Neurosanatio s.r.o., Litomyšl, 570 01, Czechia

🇨🇿

Cerebrovaskulární poradna, s.r.o., Ostrava - Poruba, 70800, Czechia

🇨🇿

Nemocnice Pardubického kraje a.s. Pardubická nemocnice Neurologická klinika, Pardubice, 532 03, Czechia

and more 27 locations

Study of Efficacy and Safety of Gabapentin to Reduce the Need for Strong Opioid Use in Head and Neck Cancer Patients.

First Posted Date
2018-11-20
Last Posted Date
2022-12-21
Lead Sponsor
University Hospital, Ghent
Registration Number
NCT03747562
Locations
🇧🇪

AZ Groeninge, Kortrijk, West-Vlaanderen, Belgium

🇧🇪

UZ Ghent, Gent, Oost-Vlaanderen, Belgium

Effectiveness of Ropinirole and Gabapentin for the Treatment of RLS in Patients on Maintenance HD

First Posted Date
2018-10-17
Last Posted Date
2022-07-12
Lead Sponsor
University of Alberta
Target Recruit Count
3
Registration Number
NCT03708237
Locations
🇨🇦

Edmonton General Continuing Care Centre, Edmonton, Canada

🇨🇦

Royal Alexandra Hospital, Edmonton, Canada

🇨🇦

Grey Nuns Community Hospital, Edmonton, Canada

and more 1 locations

Perioperative Analgesia Using Gabapentin in Head and Neck Cancer Surgery

First Posted Date
2018-09-24
Last Posted Date
2021-07-09
Lead Sponsor
University of California, Davis
Target Recruit Count
8
Registration Number
NCT03682367
Locations
🇺🇸

UC Davis Medical Center, Sacramento, California, United States

Gabapentin for Pain Management During Dilation and Evacuation

Phase 4
Completed
Conditions
Interventions
First Posted Date
2018-08-17
Last Posted Date
2020-06-18
Lead Sponsor
Medstar Health Research Institute
Target Recruit Count
130
Registration Number
NCT03635905
Locations
🇺🇸

Planned Parenthood, Washington, District of Columbia, United States

🇺🇸

MedStar Washington Hospital Center, Washington, District of Columbia, United States

Gabapentin Premedication to Reduce Postoperative Pain for Pediatric Tonsillectomy

Phase 4
Recruiting
Conditions
Interventions
First Posted Date
2018-08-10
Last Posted Date
2019-07-24
Lead Sponsor
Children's Healthcare of Atlanta
Target Recruit Count
50
Registration Number
NCT03625011
Locations
🇺🇸

Children's Healthcare of Atlanta, Atlanta, Georgia, United States

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