Gabapentin

Generic Name
Gabapentin
Brand Names
Gralise, Neurontin
Drug Type
Small Molecule
Chemical Formula
C9H17NO2
CAS Number
60142-96-3
Unique Ingredient Identifier
6CW7F3G59X
Background

Gabapentin is a structural analogue of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) that was first approved for use in the United States in 1993. It was originally developed as a novel anti-epileptic for the treatment of certain types of seizures - today it is also widely used to treat neuropathic pain. Gabapentin has some stark advantages ...

Indication

In the United States, gabapentin is officially indicated for the treatment of postherpetic neuralgia in adults and for the adjunctive treatment of partial-onset seizures, with or without secondary generalization, in patients 3 years of age and older. In Europe, gabapentin is indicated for adjunctive therapy in the treatment of partial-onset seizures, with or...

Associated Conditions
Partial-Onset Seizures, Peripheral Neuropathic Pain, Postherpetic Neuralgia
Associated Therapies
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Prevention of Persistent Opioid Use in Mothers

First Posted Date
2018-03-21
Last Posted Date
2022-05-05
Lead Sponsor
Stanford University
Target Recruit Count
78
Registration Number
NCT03472521
Locations
🇺🇸

Lucille Packard Children's Hospital, Palo Alto, California, United States

PROGRESS Trial - Prophylactic Gabapentin for Relief of Symptoms and Improved Swallowing

First Posted Date
2018-02-06
Last Posted Date
2024-07-31
Lead Sponsor
University of Chicago
Registration Number
NCT03423264
Locations
🇺🇸

University of Chicago Medical Center, Chicago, Illinois, United States

Pain Control in Children and Adolescent After Thoracic Surgery: The Effect of Gabapentin

First Posted Date
2018-01-08
Last Posted Date
2021-09-08
Lead Sponsor
National Institute for Tuberculosis and Lung Diseases, Poland
Target Recruit Count
104
Registration Number
NCT03393702
Locations
🇵🇱

Institute for Tuberculosis and Lung Diseases, Pediatric Division, Rabka-Zdrój, Małopolska, Poland

Efficacy of Multimodal Analgesia Following Hip Arthroscopy

First Posted Date
2017-11-22
Last Posted Date
2021-10-15
Lead Sponsor
Western University, Canada
Target Recruit Count
100
Registration Number
NCT03351439
Locations
🇨🇦

Fowler Kennedy Sport Medicine Clinic, London, Ontario, Canada

Gabapentin Regimens and Their Effects on Opioid Consumption

First Posted Date
2017-11-07
Last Posted Date
2021-02-18
Lead Sponsor
Brigham and Women's Hospital
Target Recruit Count
77
Registration Number
NCT03334903
Locations
🇺🇸

Brigham and Women's Faulkner Hospital, Boston, Massachusetts, United States

Gabapentin in the Post-cesarean Pain Management of Buprenorphine Patient

First Posted Date
2017-11-07
Last Posted Date
2019-02-18
Lead Sponsor
Vanderbilt University Medical Center
Registration Number
NCT03335436

Gabapentin for Bipolar & Cannabis Use Disorders

First Posted Date
2017-11-07
Last Posted Date
2020-11-13
Lead Sponsor
Medical University of South Carolina
Target Recruit Count
23
Registration Number
NCT03334721
Locations
🇺🇸

Medical University of South Carolina, Charleston, South Carolina, United States

Gabapentin for the Reduction of Radiation Therapy Induced Pain During the Treatment of Oropharyngeal Cancer

First Posted Date
2017-08-31
Last Posted Date
2022-01-26
Lead Sponsor
Henry Ford Health System
Target Recruit Count
65
Registration Number
NCT03269344
Locations
🇺🇸

Henry Ford Hospital, Detroit, Michigan, United States

The Effect of Gabapentin Used as a Preemptive to the Emergence and Development Chronic Neuropathic Pain in Patients After Spinal Cord Trauma

First Posted Date
2017-08-21
Last Posted Date
2019-03-07
Lead Sponsor
Masaryk University
Registration Number
NCT03255330
Locations
🇨🇿

Fakultní nemocnice Brno, Brno, Czechia

Imaging GABAergic/Glutamatergic Drugs in Bipolar Alcoholics Alcoholics

First Posted Date
2017-07-18
Last Posted Date
2023-12-13
Lead Sponsor
Medical University of South Carolina
Target Recruit Count
54
Registration Number
NCT03220776
Locations
🇺🇸

Medical University of South Carolina, Charleston, South Carolina, United States

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