Bisacodyl, a diphenylmethane derivative, is a commonly used over the counter stimulant laxative for occasional constipation. Both bisacodyl and picosulfate are metabolized to the same active metabolite bis-(p-hydroxyphenyl)-pyridyl-2-methane (BHPM).
Bisacodyl was patented on 25 September 1956 but has been used as a laxative since 1952.
Bisacodyl is indicated to relieve occasional constipation and irregularity.
Cooper University Hospital, Camden, New Jersey, United States
Department of Surgery, Triemli Hospital, Zurich, Switzerland, Zurich, Switzerland
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