Bisacodyl
- Generic Name
- Bisacodyl
- Brand Names
- Alophen Reformulated Jan 2008, Bi-peglyte, Bisac-evac, Carters Little Pills, Dulcolax, Fleet Mineral Oil, Gavilyte-H and Bisacodyl
- Drug Type
- Small Molecule
- Chemical Formula
- C22H19NO4
- CAS Number
- 603-50-9
- Unique Ingredient Identifier
- 10X0709Y6I
- Background
Bisacodyl, a diphenylmethane derivative, is a commonly used over the counter stimulant laxative for occasional constipation. Both bisacodyl and picosulfate are metabolized to the same active metabolite bis-(p-hydroxyphenyl)-pyridyl-2-methane (BHPM).
Bisacodyl was patented on 25 September 1956 but has been used as a laxative since 1952.
- Indication
Bisacodyl is indicated to relieve occasional constipation and irregularity.
- Associated Conditions
- Bowel movement irregularity, Constipation, Occasional Constipation
- Associated Therapies
- Bowel preparation therapy
Low-dose Laxative Improves Performance and Feasibility of Computed Tomography Colonography (CTC)
- Conditions
- Gastrointestinal Complication
- Interventions
- First Posted Date
- 2014-01-20
- Last Posted Date
- 2014-01-20
- Lead Sponsor
- Azienda Policlinico Umberto I
- Target Recruit Count
- 52
- Registration Number
- NCT02040285
- Locations
- 🇮🇹
Policlinico Umberto I, Roma, Italy
12-Week Study of Plecanatide for CIC (The CIC3 Study)
- Conditions
- Chronic Idiopathic Constipation
- Interventions
- First Posted Date
- 2013-11-13
- Last Posted Date
- 2019-12-26
- Lead Sponsor
- Bausch Health Americas, Inc.
- Target Recruit Count
- 1394
- Registration Number
- NCT01982240
- Locations
- 🇨🇦
Synergy Research Site, St-Romuald, Quebec, Canada
Effect of Octreotide on the Colonic Motility in Pediatric Patients
- Conditions
- Colonic Motility IndexConstipation
- Interventions
- First Posted Date
- 2013-08-07
- Last Posted Date
- 2015-12-21
- Lead Sponsor
- Indiana University
- Target Recruit Count
- 13
- Registration Number
- NCT01917773
- Locations
- 🇺🇸
Motility Laboratory, Division of Pediatric Gastroenterology, Hepatology and Nutrition at the James Whitcomb Riley Hospital for Children,, Indianapolis, Indiana, United States
Efficacy of 2-Liter Mixed Preparation With Bisacodyl Plus Polyethylene Glycol and 4-Liter Polyethylene Glycol for Colon Cleansing in Patients With Prior History of Colorectal Resection
- First Posted Date
- 2013-06-26
- Last Posted Date
- 2014-06-17
- Lead Sponsor
- Ospedale Santa Maria delle Croci
- Target Recruit Count
- 116
- Registration Number
- NCT01887158
- Locations
- 🇮🇹
Ospedale S.Maria delle Croci, Ravenna, RA, Italy
🇮🇹Alessandro Mussetto, Ravenna, RA, Italy
Safety and Tolerability of Oral Polyethylene Glycol (PEG 3350) Solution in Participants With Constipation (MK-8114-003)
- Conditions
- Constipation
- Interventions
- Drug: PlaceboDrug: Polyethylene Glycol (PEG 3350)
- First Posted Date
- 2013-06-24
- Last Posted Date
- 2015-03-11
- Lead Sponsor
- Bayer
- Target Recruit Count
- 65
- Registration Number
- NCT01885104
Study About Effect of Preoperative Bowel Preparation Versus no Bowel Preparation Before Spinal Surgery
- Conditions
- ConstipationIleusSurgery
- Interventions
- First Posted Date
- 2013-06-18
- Last Posted Date
- 2013-06-18
- Lead Sponsor
- Oslo University Hospital
- Target Recruit Count
- 45
- Registration Number
- NCT01879605
- Locations
- 🇳🇴
Oslo Universitetssykehus, Oslo, Norway
Multidisciplinary Approach Versus Conventional Approach in Colonic Preparation of Hospitalized Patients
- Conditions
- Bowel Preparation for Colonoscopy
- Interventions
- Behavioral: EducationOther: Fiber free dietDietary Supplement: AdjuvantsDrug: Polyethylene glycol (PEG)
- First Posted Date
- 2013-05-15
- Last Posted Date
- 2013-05-15
- Lead Sponsor
- Corporacion Parc Tauli
- Target Recruit Count
- 162
- Registration Number
- NCT01853709
- Locations
- 🇪🇸
Hospital de Sabadell, Sabadell, Barcelona, Spain
Bowel Cleansing for Colonoscopy: Comparison Between a Same Day Low-Volume Preparation and a Conventional 4L Split One
- Conditions
- Colonoscopy
- Interventions
- First Posted Date
- 2012-09-14
- Last Posted Date
- 2012-09-19
- Lead Sponsor
- European Institute of Oncology
- Target Recruit Count
- 164
- Registration Number
- NCT01685853
- Locations
- 🇮🇹
European Institute of Oncology, Milan, Italy
Improving Bowel Preparation for the Colon Capsule
- Conditions
- Quality of Bowel Preparation for the Colon CapsuleColon Capsule Completion RatesColon Capsule Polyp Detection
- Interventions
- Drug: PicosalaxProcedure: Colon capsuleProcedure: Colonoscopy
- First Posted Date
- 2012-08-01
- Last Posted Date
- 2015-12-03
- Lead Sponsor
- Queen's University
- Target Recruit Count
- 20
- Registration Number
- NCT01655095
- Locations
- 🇨🇦
Hotel Dieu Hospital, Kingston, Ontario, Canada
Colonoscopy Preparation Optimization for INpatients- COIN Study
- Conditions
- EndoscopyBowel Preparation Solutions
- Interventions
- First Posted Date
- 2012-06-25
- Last Posted Date
- 2013-01-30
- Lead Sponsor
- St. Joseph's Healthcare Hamilton
- Target Recruit Count
- 126
- Registration Number
- NCT01627171
- Locations
- 🇨🇦
St Joseph Hospital, Hamilton, Ontario, Canada
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.