Telmisartan

Generic Name
Telmisartan
Brand Names
Actelsar Hct, Micardis, Micardis-hct, Pritor, Twynsta, Tolura, Kinzalmono (previously Telmisartan Boehringer Ingelheim Pharma KG), Telmisartan Teva Pharma, Telmisartan Actavis
Drug Type
Small Molecule
Chemical Formula
C33H30N4O2
CAS Number
144701-48-4
Unique Ingredient Identifier
U5SYW473RQ
Background

Telmisartan is an angiotensin II receptor antagonist (ARB) used in the management of hypertension. Generally, angiotensin II receptor blockers (ARBs) such as telmisartan bind to the angiotensin II type 1 (AT1) receptors with high affinity, causing inhibition of the action of angiotensin II on vascular smooth muscle, ultimately leading to a reduction in arter...

Indication

Used alone or in combination with other classes of antihypertensives for the treatment of hypertension. Also used in the treatment of diabetic nephropathy in hypertensive patients with type 2 diabetes mellitus, as well as the treatment of congestive heart failure (only in patients who cannot tolerate ACE inhibitors).

Associated Conditions
Cardiovascular Events, Diabetic Nephropathy, Heart Failure, Hypertension
Associated Therapies
-

Comparison of Effects of Telmisartan and Valsartan on Neointima Volume in Diabetes

First Posted Date
2008-01-24
Last Posted Date
2015-09-03
Lead Sponsor
Korea University Anam Hospital
Target Recruit Count
72
Registration Number
NCT00599885
Locations
🇰🇷

Korea University Anam Hospital, Seoul, Korea, Republic of

Regulation of Inflammatory Parameters by Telmisartan in Hypertensive Patients

First Posted Date
2007-11-19
Last Posted Date
2010-07-15
Lead Sponsor
Ludwig-Maximilians - University of Munich
Target Recruit Count
56
Registration Number
NCT00560430
Locations
🇩🇪

Center for Cardiovascular Research, University Berlin, Berlin, Germany

🇩🇪

Med. Dept. 2, University Munich, Munich, Germany

Effect of the Known Antihypertensive Drug Telmisartan on Red Blood Cells and Circulation in the Smallest Blood Vessels

First Posted Date
2007-11-16
Last Posted Date
2009-01-29
Lead Sponsor
RWTH Aachen University
Target Recruit Count
40
Registration Number
NCT00559286
Locations
🇩🇪

University Hospital, Aachen, NRW, Germany

Filtered Trial for Telmisartan 40mg Non-responder

Phase 3
Completed
Conditions
First Posted Date
2007-10-30
Last Posted Date
2014-01-30
Lead Sponsor
Boehringer Ingelheim
Target Recruit Count
314
Registration Number
NCT00550953
Locations
🇯🇵

1235.14.003 Boehringer Ingelheim Investigational Site, Musashino, Tokyo, Japan

🇯🇵

1235.14.002 Boehringer Ingelheim Investigational Site, Chofu, Tokyo, Japan

🇯🇵

1235.14.004 Boehringer Ingelheim Investigational Site, Osaka, Osaka, Japan

and more 2 locations

A Randomized, Double-Blind, Active Control Trial Comparing Effects of Telmisartan, Candesartan and Amlodipine, Alone or Plus Metformin, on Non-Diabetic, Obese Hypertensive Patients

First Posted Date
2007-10-02
Last Posted Date
2013-05-14
Lead Sponsor
Third Military Medical University
Target Recruit Count
360
Registration Number
NCT00538486
Locations
🇨🇳

The third hospital affiliated to the Third Military Medical University, Chongqing, China

Telmisartan in Haemodialysis Patients With Chronic Heart Failure

Phase 4
Completed
Conditions
First Posted Date
2007-06-25
Last Posted Date
2008-10-17
Lead Sponsor
University of Campania "Luigi Vanvitelli"
Target Recruit Count
351
Registration Number
NCT00490958
Locations
🇮🇹

Chair of Cardiology Second University of Naples, Naples, Italy

Telmisartan and Renal Perfusion in Patients With Metabolic Syndrome

Phase 3
Completed
Conditions
First Posted Date
2007-03-27
Last Posted Date
2012-07-10
Lead Sponsor
University of Erlangen-Nürnberg Medical School
Target Recruit Count
30
Registration Number
NCT00452192
Locations
🇩🇪

Clinical Research Center, Department of Nephrology and Hypertension, University of Erlangen-Nürnberg, Erlangen, Germany

Combination of Telmisartan and Simvastatin in the Treatment of Hypertension and Hypercholesterolemia

Phase 3
Completed
Conditions
First Posted Date
2006-04-20
Last Posted Date
2013-11-01
Lead Sponsor
Boehringer Ingelheim
Target Recruit Count
1695
Registration Number
NCT00316095
Locations
🇫🇷

ALTI, Angers, France

🇰🇷

Hallym University Sacred Heart Hospital, Kyunggi-do, Korea, Republic of

🇳🇱

Andromed Eindhoven, Eindhoven, Netherlands

and more 20 locations

Effectiveness of Candesartan and Telmisartan on Morning Hypertension in Japanese Obese Patients

Not Applicable
Conditions
First Posted Date
2006-02-08
Last Posted Date
2007-01-11
Lead Sponsor
Saitama Medical University
Target Recruit Count
300
Registration Number
NCT00288717
Locations
🇯🇵

Saitama Medical School Department of Renal Medicine, Saitama City, Saitama, Japan

HALT Progression of Polycystic Kidney Disease Study A

First Posted Date
2006-01-30
Last Posted Date
2020-04-21
Lead Sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Target Recruit Count
558
Registration Number
NCT00283686
Locations
🇺🇸

University of Colorado Health Sciences Center, Aurora, Colorado, United States

🇺🇸

Tufts University-New England Medical Center, Boston, Massachusetts, United States

🇺🇸

Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States

and more 4 locations
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