Telmisartan

Generic Name: Telmisartan

Brand Names: Actelsar Hct, Micardis, Micardis-hct, Pritor, Twynsta, Tolura, Kinzalmono (previously Telmisartan Boehringer Ingelheim Pharma KG), Telmisartan Teva Pharma, Telmisartan Actavis

Drug Type: Small Molecule

Chemical Formula: C_₃₃H_₃₀N_₄O_₂

CAS Number: 144701-48-4

Unique Ingredient Identifier: U5SYW473RQ

Background: Telmisartan is an angiotensin II receptor antagonist (ARB) used in the management of hypertension. Generally, angiotensin II receptor blockers (ARBs) such as telmisartan bind to the angiotensin II type 1 (AT1) receptors with high affinity, causing inhibition of the action of angiotensin II on vascular smooth muscle, ultimately leading to a reduction in arter...

Indication: Used alone or in combination with other classes of antihypertensives for the treatment of hypertension. Also used in the treatment of diabetic nephropathy in hypertensive patients with type 2 diabetes mellitus, as well as the treatment of congestive heart failure (only in patients who cannot tolerate ACE inhibitors).

Associated Conditions: Cardiovascular Events, Diabetic Nephropathy, Heart Failure, Hypertension

Associated Therapies: -

Clinical Trials

Study of the Effectiveness of Telmisartan in Slowing the Progression of Abdominal Aortic Aneurysms

Phase 4

Completed

Conditions: Abdominal Aortic Aneurysm

Interventions: Drug: Placebo
Drug: Telmisartan

First Posted Date: 2012-09-11

Last Posted Date: 2020-05-26

Lead Sponsor: Palo Alto Veterans Institute for Research

Target Recruit Count: 22

Registration Number: NCT01683084

Locations: 🇺🇸
VA Palo Alto Health Care System, Palo Alto, California, United States

A Clinical Trial for People HIV+ Age > 50 at Risk for Heart Disease

Phase 2

Completed

Conditions: Endothelial Dysfunction

Interventions: Drug: Telmisartan

First Posted Date: 2012-04-17

Last Posted Date: 2014-12-08

Lead Sponsor: University of California, Los Angeles

Target Recruit Count: 17

Registration Number: NCT01578772

Locations: 🇺🇸
UCLA CARE Center, Los Angeles, California, United States

Nifedipine vs Telmisartan on Prevention of Atrial Fibrillation (AF) Recurrence in Hypertensive Patients With AF

Phase 4

Completed

Conditions: Atrial Fibrillation

Interventions: Drug: Telmisartan
Drug: Nifedipine,

First Posted Date: 2011-09-16

Last Posted Date: 2012-11-16

Lead Sponsor: The Second Affiliated Hospital of Chongqing Medical University

Target Recruit Count: 160

Registration Number: NCT01435161

Locations: 🇨🇳
2ndChongqingMU, Chongqing, Chongqing, China

Bioequivalence Study of Telmisartan Between Telmisartan 80 mg/Amlodipine 5 mg FDC Tablet and Telmisartan 80 mg Tab and Amlodipine 5 mg Tab Concomitant Use

Phase 1

Completed

Conditions: Healthy

Interventions: Drug: Telmisartan/Amlodipin FDC
Drug: Telmisartan
Drug: Amlodipin

First Posted Date: 2011-04-29

Last Posted Date: 2014-03-28

Lead Sponsor: Boehringer Ingelheim

Target Recruit Count: 64

Registration Number: NCT01344629

Locations: 🇯🇵
1235.28.001 Boehringer Ingelheim Investigational Site, Kumamoto, Kumamoto, Japan

Twynsta Study With Lifestyle Modifications in Korean Patients With Hypertension

Completed

Conditions: Hypertension

Interventions: Drug: Telmisartan
Drug: amlodipine

First Posted Date: 2011-03-16

Last Posted Date: 2015-09-21

Lead Sponsor: Boehringer Ingelheim

Target Recruit Count: 2089

Registration Number: NCT01316419

Locations: 🇰🇷
Boehringer Ingelheim Investigational Site 51, Jeju, Korea, Republic of
🇰🇷
Boehringer Ingelheim Investigational Site 54, Chonbuk, Korea, Republic of
🇰🇷
Boehringer Ingelheim Investigational Site 55, Busan, Korea, Republic of

and more 52 locations

Telmisartan Versus Losartan in Kidney Transplantation

Phase 2

Completed

Conditions: Renal Transplant

Interventions: Drug: Telmisartan
Drug: Losartan

First Posted Date: 2010-10-20

Last Posted Date: 2014-02-25

Lead Sponsor: Mario Negri Institute for Pharmacological Research

Target Recruit Count: 20

Registration Number: NCT01224860

Locations: 🇮🇹
Mario negri Institute - Clinical Research Center for Rare Diseases, Ranica, Bergamo, Italy

Telmisartan 80mg Non-responder Trial

Phase 3

Completed

Conditions: Hypertension

Interventions: Drug: Telmisartan
Drug: Telmisartan and amlodipine

First Posted Date: 2010-10-18

Last Posted Date: 2014-06-27

Lead Sponsor: Boehringer Ingelheim

Target Recruit Count: 174

Registration Number: NCT01222520

Locations: 🇯🇵
1235.36.04 Boehringer Ingelheim Investigational Site, Hiroshima, Hiroshima, Japan
🇯🇵
1235.36.02 Boehringer Ingelheim Investigational Site, Shinjuku-ku, Tokyo, Japan
🇯🇵
1235.36.01 Boehringer Ingelheim Investigational Site, Chuo-ku,Tokyo, Japan

and more 1 locations

Beta Blockers and Angiotensin Receptor Blockers in Bicuspid Aortic Valve Disease Aortopathy (BAV Study)

Phase 3

Terminated

Conditions: Cardiac Disease

Interventions: Drug: Telmisartan
Drug: Atenolol

First Posted Date: 2010-09-16

Last Posted Date: 2019-09-18

Lead Sponsor: Hamilton Health Sciences Corporation

Target Recruit Count: 85

Registration Number: NCT01202721

Locations: 🇨🇦
Hamilton Health Sciences-General, Hamilton, Ontario, Canada
🇨🇦
St. Michael's Hospital, Toronto, Ontario, Canada
🇨🇦
Cité de la Santé de Laval, Laval, Quebec, Canada

and more 10 locations

Telmisartan, Amlodipine and Flow Mediated Dilation

Phase 4

Conditions: Hypertension

Interventions: Drug: Telmisartan
Drug: Olmesartan medoxomil
Drug: Amlodipine
Drug: Hydrochlorothiazide

First Posted Date: 2010-08-12

Last Posted Date: 2011-07-12

Lead Sponsor: Johannes Gutenberg University Mainz

Target Recruit Count: 576

Registration Number: NCT01180205

Locations: 🇩🇪
Universitätsmedizin Mainz, Mainz, Rheinland-Pfalz, Germany

CKD-828 Primary Hypertension Trial(Dose-selection)

Phase 2

Completed

Conditions: Hypertension

Interventions: Drug: Placebo
Drug: S-Amlodipine, Telmisartan
Drug: S-Amlodipine
Drug: Telmisartan

First Posted Date: 2010-05-21

Last Posted Date: 2011-04-26

Lead Sponsor: Chong Kun Dang Pharmaceutical

Target Recruit Count: 430

Registration Number: NCT01128322

Locations: 🇰🇷
Hallym University Sacred Heart Hospital, Anyang, Korea, Republic of
🇰🇷
Korea University Guro Hospital, Seoul, Korea, Republic of
🇰🇷
DonGuk University International Hospital, Goyang, Korea, Republic of

and more 23 locations

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