Telmisartan

Generic Name
Telmisartan
Brand Names
Actelsar Hct, Micardis, Micardis-hct, Pritor, Twynsta, Tolura, Kinzalmono (previously Telmisartan Boehringer Ingelheim Pharma KG), Telmisartan Teva Pharma, Telmisartan Actavis
Drug Type
Small Molecule
Chemical Formula
C33H30N4O2
CAS Number
144701-48-4
Unique Ingredient Identifier
U5SYW473RQ
Background

Telmisartan is an angiotensin II receptor antagonist (ARB) used in the management of hypertension. Generally, angiotensin II receptor blockers (ARBs) such as telmisartan bind to the angiotensin II type 1 (AT1) receptors with high affinity, causing inhibition of the action of angiotensin II on vascular smooth muscle, ultimately leading to a reduction in arter...

Indication

Used alone or in combination with other classes of antihypertensives for the treatment of hypertension. Also used in the treatment of diabetic nephropathy in hypertensive patients with type 2 diabetes mellitus, as well as the treatment of congestive heart failure (only in patients who cannot tolerate ACE inhibitors).

Associated Conditions
Cardiovascular Events, Diabetic Nephropathy, Heart Failure, Hypertension
Associated Therapies
-

HIV and Fat Accumulation

Phase 2
Completed
Conditions
Interventions
First Posted Date
2010-03-17
Last Posted Date
2019-02-04
Lead Sponsor
University of California, Los Angeles
Target Recruit Count
35
Registration Number
NCT01088295
Locations
🇺🇸

UCLA CARE Center, Los Angeles, California, United States

Telmisartan as an Adjunctive Treatment for Metabolic Problems in Patients With Schizophrenia

First Posted Date
2009-09-22
Last Posted Date
2018-06-19
Lead Sponsor
University of Massachusetts, Worcester
Target Recruit Count
66
Registration Number
NCT00981526
Locations
🇺🇸

University of Massachusetts Medical School, Worcester, Massachusetts, United States

Study of Hypertensive Population Under Treatment With Telmisartan in Real Clinical Conditions With the Goal to Control Early Morning Blood Pressure Rise

Completed
Conditions
First Posted Date
2009-07-27
Last Posted Date
2019-11-05
Lead Sponsor
Boehringer Ingelheim
Target Recruit Count
18299
Registration Number
NCT00946829
Locations
🇾🇪

Boehringer Ingelheim Investigational Site, Boehringer Ingelheim Investigational Site, Yemen

The Effects of Peroxisome Proliferators Activated Receptor-Gamma (PPAR-γ) Agonists on Certain Biochemical and Inflammatory Markers in Metabolic Syndrome

Phase 4
Completed
Conditions
Interventions
First Posted Date
2009-06-23
Last Posted Date
2009-06-24
Lead Sponsor
Aligarh Muslim University
Target Recruit Count
110
Registration Number
NCT00926341
Locations
🇮🇳

Department of Medicine, J.N.Medical,College, AMU,Aligarh, Aligarh, Uttar Pradesh, India

Telmisartan 80mg Plus Hydrochlorothiazide 25mg First Line in Moderate or Severe Hypertension

Phase 4
Completed
Conditions
Interventions
First Posted Date
2009-06-23
Last Posted Date
2014-06-27
Lead Sponsor
Boehringer Ingelheim
Target Recruit Count
894
Registration Number
NCT00926289
Locations
🇺🇸

502.550.01007 Boehringer Ingelheim Investigational Site, Greensboro, North Carolina, United States

🇨🇳

502.550.86002 Boehringer Ingelheim Investigational Site, Shanghai, China

🇨🇳

502.550.86007 Boehringer Ingelheim Investigational Site, Tianjin, China

and more 103 locations

Efficacy and Safety of Aliskiren 300 mg Compared to Telmisartan 80 mg After 1 Week of Treatment Withdrawal

First Posted Date
2009-03-19
Last Posted Date
2011-07-22
Lead Sponsor
Novartis
Target Recruit Count
822
Registration Number
NCT00865020
Locations
🇻🇪

Investigative Site, Caracas, Venezuela

🇭🇺

Invesitagtive Site, Budapest, Hungary

Telmisartan and Amlodipine Fixed Dose Combination [FDC] Trial for the Treatment of Severe Hypertension

First Posted Date
2009-03-12
Last Posted Date
2014-05-20
Lead Sponsor
Boehringer Ingelheim
Target Recruit Count
858
Registration Number
NCT00860262
Locations
🇧🇬

1235.20.008 Boehringer Ingelheim Investigational Site, Sofia, Bulgaria

🇭🇺

1235.20.152 Boehringer Ingelheim Investigational Site, Budapest, Hungary

🇷🇴

1235.20.254 Boehringer Ingelheim Investigational Site, Iasi, Romania

and more 134 locations

Study Evaluating the Efficacy of Nifedipine GITS - Telmisartan Combination in Blood Pressure Control.

First Posted Date
2008-09-10
Last Posted Date
2014-12-05
Lead Sponsor
Bayer
Target Recruit Count
405
Registration Number
NCT00750113

Telmisartan Versus Ramipril After Acute Coronary Syndrome

First Posted Date
2008-06-20
Last Posted Date
2008-06-20
Lead Sponsor
Catholic University of the Sacred Heart
Target Recruit Count
50
Registration Number
NCT00702936
Locations
🇮🇹

Catholic University of the Sacred Heart, Rome, Italy

J-TARGET,Japanese Telmisartan Study for Antihypertensive Good Effect in Long Term Observation

Completed
Conditions
Interventions
First Posted Date
2008-04-16
Last Posted Date
2016-08-25
Lead Sponsor
Boehringer Ingelheim
Target Recruit Count
21471
Registration Number
NCT00659581
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